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4.1.1.71: 2-oxoglutarate decarboxylase

This is an abbreviated version!
For detailed information about 2-oxoglutarate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.71

Reaction

2-oxoglutarate
=
succinate semialdehyde
+
CO2

Synonyms

ALKBH4, alpha-ketoglutarate decarboxylase, alpha-ketoglutaric decarboxylase, alpha-KGD, decarboxylase, oxoglutarate, E1o, Fe(II)/2OG-dependent decarboxylase, KDC, Kgd, oxoglutarate decarboxylase, pre-2-oxoglutarate decarboxylase, Rv1248c

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.71 2-oxoglutarate decarboxylase

pH Range

pH Range on EC 4.1.1.71 - 2-oxoglutarate decarboxylase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4 - 6.5
-
active in the range
6
-
34% residual activity
6 - 9
-
pH 6.0: 65% of activity maximum, pH 9.0: 55% of activity maximum
6.5 - 7
-
the optimal pH for the enzyme is at the range of 6.5-7.0. The activity of the enzyme is 34% and 17% at pH 6.0 and 8.0, respectively
8
-
17% residual activity