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4.1.1.71: 2-oxoglutarate decarboxylase

This is an abbreviated version!
For detailed information about 2-oxoglutarate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.71

Reaction

2-oxoglutarate
=
succinate semialdehyde
+
CO2

Synonyms

ALKBH4, alpha-ketoglutarate decarboxylase, alpha-ketoglutaric decarboxylase, alpha-KGD, decarboxylase, oxoglutarate, E1o, Fe(II)/2OG-dependent decarboxylase, KDC, Kgd, oxoglutarate decarboxylase, pre-2-oxoglutarate decarboxylase, Rv1248c

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.71 2-oxoglutarate decarboxylase

Reference

Reference on EC 4.1.1.71 - 2-oxoglutarate decarboxylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Faff-Michalak, L.; Albrecht, J.
The two catalytic components of the 2-oxoglutarate dehydrogenase complex in rat cerebral synaptic and nonsynaptic mitochondria: Comparison of the response to in vitro treatment with ammonia, hyperammonemia, and hepatic encephalopathy
Neurochem. Res.
18
119-123
1993
Rattus norvegicus
Manually annotated by BRENDA team
Shigeoka, S.; Onishi, T.; Maeda, K.; Nakano, Y.; Kitaoka, S.
Occurence of thiamin pyrophopshate-dependent 2-oxoglutarate decarboxylase in mitochondria of Euglena gracilis
FEBS Lett.
195
43-47
1986
Euglena gracilis
-
Manually annotated by BRENDA team
Shigeoka, S.; Nakano, Y.
Characterization and molecular properties of 2-oxoglutarate decarboxylase from Euglena gracilis
Arch. Biochem. Biophys.
288
22-28
1991
Euglena gracilis
Manually annotated by BRENDA team
Kapol, R.; Radler, F.
Purification and characterization of 2-oxoglutarate decarboxylase of Leuconostoc mesenteroides
J. Gen. Microbiol.
136
1497-1499
1990
Oenococcus oeni, Oenococcus oeni B 211
-
Manually annotated by BRENDA team
Shigeoka, S.; Hanaoka, T.; Kishi, N.; Nakano, Y.
Effect of L-glutamate on 2-oxoglutarate decarboxylase in Euglena gracilis
Biochem. J.
282
319-323
1992
Euglena gracilis, Euglena gracilis SM-ZK
-
Manually annotated by BRENDA team
Shigeoka, S.; Nakano, Y.
The effect of thiamin on the activation of thiamin pyrophosphate-dependent 2-oxoglutarate decarboxylase in Euglena gracilis
Biochem. J.
292
463-467
1993
Euglena gracilis
-
Manually annotated by BRENDA team
Tian, J.; Bryk, R.; Itoh, M.; Suematsu, M.; Nathan, C.
Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase
Proc. Natl. Acad. Sci. USA
102
10670-10675
2005
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Bjornstad, L.G.; Zoppellaro, G.; Tomter, A.B.; Falnes, P.O.; Andersson, K.K.
Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4
Biochem. J.
434
391-398
2011
Homo sapiens
Manually annotated by BRENDA team
Wagner, T.; Barilone, N.; Alzari, P.M.; Bellinzoni, M.
A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (alpha-ketoglutarate decarboxylase)
Biochem. J.
457
425-434
2014
Mycolicibacterium smegmatis (A0R3B1)
Manually annotated by BRENDA team
Wagner, T.; Bellinzoni, M.; Wehenkel, A.; OHare, H.M.; Alzari, P.M.
Functional plasticity and allosteric regulation of alpha-ketoglutarate decarboxylase in central mycobacterial metabolism
Chem. Biol.
18
1011-1020
2011
Mycobacterium tuberculosis, Mycolicibacterium smegmatis (A0R2B1), Mycolicibacterium smegmatis mc(2)155 / ATCC 700084 (A0R2B1), Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Sykes, S.; Szempruch, A.; Hajduk, S.
The Krebs cycle enzyme alpha-ketoglutarate decarboxylase is an essential glycosomal protein in bloodstream African trypanosomes
Eukaryot. Cell
14
206-215
2015
Trypanosoma brucei
Manually annotated by BRENDA team
Lei, G.; Wang, X.; Lai, C.; Li, Z.M.; Zhang, W.; Xie, C.; Wang, F.; Wu, X.; Li, Z.
Expression and biochemical characterization of alpha-ketoglutarate decarboxylase from cyanobacterium Synechococcus sp. PCC7002
Int. J. Biol. Macromol.
114
188-193
2018
Synechococcus sp. PCC 7002
Manually annotated by BRENDA team