Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.1.1.71: 2-oxoglutarate decarboxylase

This is an abbreviated version!
For detailed information about 2-oxoglutarate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.71

Reaction

2-oxoglutarate
=
succinate semialdehyde
+
CO2

Synonyms

ALKBH4, alpha-ketoglutarate decarboxylase, alpha-ketoglutaric decarboxylase, alpha-KGD, decarboxylase, oxoglutarate, E1o, Fe(II)/2OG-dependent decarboxylase, KDC, Kgd, oxoglutarate decarboxylase, pre-2-oxoglutarate decarboxylase, Rv1248c

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.71 2-oxoglutarate decarboxylase

Activating Compound

Activating Compound on EC 4.1.1.71 - 2-oxoglutarate decarboxylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
2-oxoglutarate
-
-
citrate
-
-
DL-malate
-
-
fumarate
-
-
L-alanine
-
-
L-aspartate
-
-
L-glutamate
-
activation is abolished by the simultaneous addition of cycloheximide
L-lactate
-
-
propionate
-
-
pyruvate
-
-
succinate
-
-
thiamine
-
the activation of enzyme by thiamine is caused by two mechanism, the increase in the apoenzyme of enzyme by thiamine added exogenously is attributable to the conversion from the premature form to the mature form of enzyme during import into the mitochondria from cytosol, 1,10-phenanthroline, 2,4-dinitrophenol, carbonyl cyanide m-chlorophenylhydrazone inhibit activation