4.1.1.6: cis-aconitate decarboxylase

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For detailed information about cis-aconitate decarboxylase, go to the full flat file.

Reaction

Synonyms

Aconitate decarboxylase, CAD, CAD1, CadA, cis-aconitate decarboxylase, cis-Aconitic acid decarboxylase, Decarboxylase, aconitate

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.1 Carboxy-lyases

                4.1.1.6 cis-aconitate decarboxylase

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Results	in table
1	Activating Compound
23	AA Sequence
1	Application
1	CAS Registry Number
10	Cloned(Commentary)
10	Disease/ Diagnostics
5	General Information
1	General Stability
9	Inhibitors
1	KM Value [mM]
10	Localization
4	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
30	Organism
3	Pathway
2	PDB ID
4	pH Optimum
1	pH Range
3	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
28	Reference
1	Renatured (Commentary)
11	Source Tissue
1	Specific Activity [micromol/min/mg]
30	Substrates and Products (Substrate)
3	Subunits
47	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]

Systematic Name

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Systematic Name on EC 4.1.1.6 - cis-aconitate decarboxylase

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SYSTEMATIC NAME

IUBMB Comments

cis-aconitate carboxy-lyase (itaconate-forming)

The enzyme has been characterized from the fungus Aspergillus terreus and from human macrophages. cf. EC 4.1.1.113, trans-aconitate decarboxylase.