4.1.1.53: phenylalanine decarboxylase

This is an abbreviated version!
For detailed information about phenylalanine decarboxylase, go to the full flat file.

Reaction

Synonyms

AADC, amino acid decarboxylase, Aromatic L-amino acid decarboxylase, Decarboxylase, phenylalanine, disA, L-Phenylalanine decarboxylase, L-tyrosine/L-phenylalanine decarboxylase, More, PDC, PDC1, PDC2, phenylalanine decarboxylase 1, phenylalanine decarboxylase 2

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.1 Carboxy-lyases

                4.1.1.53 phenylalanine decarboxylase

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Results	in table
1	Activating Compound
6	AA Sequence
2	Application
1	CAS Registry Number
5	Cloned(Commentary)
12	Cofactor
90	Disease/ Diagnostics
2	Expression
3	General Information
9	Inhibitors
8	KM Value [mM]
8	Natural Substrates/ Products (Substrates)
21	Organism
4	Pathway
7	pH Optimum
2	Protein Variants
5	Purification (Commentary)
1	Reaction
1	Reaction Type
20	Reference
13	Source Tissue
7	Specific Activity [micromol/min/mg]
1	Storage Stability
47	Substrates and Products (Substrate)
17	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]

Inhibitors

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Inhibitors on EC 4.1.1.53 - phenylalanine decarboxylase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

5-Aminooxymethyl-2-bromophenol

Rattus norvegicus

-

brocresine, 75 mg/kg body mass cause 98% inhibition of liver enzyme in vivo

4705

5-hydroxytryptophan

Cavia aperea

-

complete inhibition at 0.001 mM

4704

alpha-Methyl-3,4-dihydroxyphenylalanine

Cavia aperea

-

competitive

4704

alpha-Methyl-5-hydroxyphenylalanine

Cavia aperea

-

-

4704

alpha-Methyl-m-tyrosine

Cavia aperea

-

-

4704

alpha-Methyltryptophan

Cavia aperea

-

-

4704

N1-(DL-Seryl)-N2-(2,3,4)-trihydroxybenzyl hydrazine

Rattus norvegicus

-

50 mg/kg cause 99% inhibition of liver enzyme in vivo

4705

p-chloromercuribenzoate

Cavia aperea

-

complete inhibition at 0.01 mM

4704

tryptamine

Micrococcus percitreus

-

42% inhibition at 0.1% v/v

4708