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4.1.1.43: phenylpyruvate decarboxylase

This is an abbreviated version!
For detailed information about phenylpyruvate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.43

Reaction

phenylpyruvate
=
phenylacetaldehyde
+
CO2

Synonyms

ARO10, Decarboxylase, phenylpyruvate, KDC, phenyl/indolepyruvate decarboxylase, phenylpyruvate decarboxylase, PpdA, PPDC, YDR380W

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.43 phenylpyruvate decarboxylase

KM Value

KM Value on EC 4.1.1.43 - phenylpyruvate decarboxylase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5.51
2-ketohexanoic acid
-
in 10 mM MES, 2.5 mM MgSO4, 0.1 mM thiamine diphosphate, 0.35 mM NADH, and 0.125 units alcohol dehydrogenase, at pH 6.5 and 30°C
0.09
2-oxo-4-phenylbutanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
5.5 - 7.6
2-oxobutanoic acid
0.17 - 1
2-oxohexanoic acid
0.37 - 2.1
2-oxopentanoic acid
8.5
3-methyl-2-oxobutanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
3.1
3-methyl-2-oxopentanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
0.09
4-hydroxyphenylpyruvate
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
0.9
4-methyl-2-oxopentanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
0.64
4-methylthio-2-oxobutanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
1.91
4-phenyl-2-oxobutanoic acid
-
in 10 mM MES, 2.5 mM MgSO4, 0.1 mM thiamine diphosphate, 0.35 mM NADH, and 0.125 units alcohol dehydrogenase, at pH 6.5 and 30°C
0.3
5-phenyl-2-oxopentanoic acid
-
in 10 mM MES, 2.5 mM MgSO4, 0.1 mM thiamine diphosphate, 0.35 mM NADH, and 0.125 units alcohol dehydrogenase, at pH 6.5 and 30°C
0.03 - 0.13
Indole-3-pyruvate
0.0051 - 1.13
phenylpyruvate
5.5 - 25
Pyruvic acid