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4.1.1.43: phenylpyruvate decarboxylase

This is an abbreviated version!
For detailed information about phenylpyruvate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.43

Reaction

phenylpyruvate
=
phenylacetaldehyde
+
CO2

Synonyms

ARO10, Decarboxylase, phenylpyruvate, KDC, phenyl/indolepyruvate decarboxylase, phenylpyruvate decarboxylase, PpdA, PPDC, YDR380W

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.43 phenylpyruvate decarboxylase

KCat KM Value

KCat KM Value on EC 4.1.1.43 - phenylpyruvate decarboxylase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
19
2-oxo-4-phenylbutanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
0.007 - 0.52
2-oxobutanoic acid
0.42 - 13
2-oxohexanoic acid
0.4 - 3.7
2-oxopentanoic acid
2.2
3-methyl-2-oxobutanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
3.5
3-methyl-2-oxopentanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
125
4-hydroxyphenylpyruvate
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
11
4-methyl-2-oxopentanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
12
4-methylthio-2-oxobutanoic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
0.35
benzoylformic acid
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
200
Indole-3-pyruvate
wild type enzyme, in 100 mM KPO4 buffer (pH 7.0), 1 mM MgSO4, 0.5 mM thiamine diphosphate, at pH 7.0 and 30°C
0.0058 - 200
phenylpyruvate
0.003 - 0.07
Pyruvic acid