4.1.1.37: uroporphyrinogen decarboxylase
This is an abbreviated version!
For detailed information about uroporphyrinogen decarboxylase, go to the full flat file.
Word Map on EC 4.1.1.37
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4.1.1.37
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porphyria
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cutanea
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tarda
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heme
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erythrocyte
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porphyrinogenic
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hexachlorobenzene
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urinary
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hepatoerythropoietic
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porphobilinogen
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overload
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photosensitivity
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ferrochelatase
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protoporphyrin
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hemochromatosis
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5-aminolaevulinate
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heptacarboxylic
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hexachlorobenzene-induced
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hypertrichosis
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phlebotomy
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erythropoietic
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delta-aminolaevulinic
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polyhalogenated
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5-aminolevulinic
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protoporphyrinogen
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uroporphyria
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tetrapyrrole
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sun-exposed
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blister
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siderosis
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diagnostics
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3,4,3\',4\'-tetrachlorobiphenyl
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medicine
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hcb-induced
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miliae
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coproporphyria
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bulla
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agriculture
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hepta
- 4.1.1.37
- porphyria
-
cutanea
- tarda
- heme
- erythrocyte
-
porphyrinogenic
- hexachlorobenzene
- urinary
-
hepatoerythropoietic
- porphobilinogen
- overload
-
photosensitivity
-
ferrochelatase
- protoporphyrin
- hemochromatosis
-
5-aminolaevulinate
-
heptacarboxylic
-
hexachlorobenzene-induced
- hypertrichosis
-
phlebotomy
-
erythropoietic
-
delta-aminolaevulinic
-
polyhalogenated
-
5-aminolevulinic
- protoporphyrinogen
-
uroporphyria
- tetrapyrrole
-
sun-exposed
- blister
- siderosis
- diagnostics
-
3,4,3\',4\'-tetrachlorobiphenyl
- medicine
-
hcb-induced
-
miliae
- coproporphyria
- bulla
- agriculture
-
hepta
Reaction
Synonyms
ch-UroD, Decarboxylase, uroporphyrinogen, Hem12p, PCL, Porphyrinogen carboxy-lyase, rl-UroD, tobacco UROD, UORO-D, UPD, URO-D, Uro-decarboxylase, uro-III decarboxylase, UroD, UROD protein, UROD1, uroporphyrinogen decarboxylase, uroporphyrinogen decarboxylase 1, Uroporphyrinogen III decarboxylase, uroporphyrinogen-decarboxylase, uroporphyrinogen-III decarboxylase
ECTree
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General Information
General Information on EC 4.1.1.37 - uroporphyrinogen decarboxylase
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malfunction
metabolism
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hepatoerythropoietic porphyria results from a deficiency of uroporphyrinogen decarboxylase
malfunction
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UROD knockdown plus radiation induces caspase-mediated apoptosis and cell cycle arrest in head and neck cancer cells in vitro and suppresses the in vivo tumor-forming capacity of head and neck cancer cells, as well as delays the growth of established tumor xenografts in mice
malfunction
humans deficient in UROD present with porphyria cutanea tarda, a condition characterized by light-sensitive dermatitis, excretion of excess uroporphyrins, and associated hepatic porphyrin accumulation
metabolism
uroporphyrinogen decarboxylase, Hem12p, is involved in the 5th step of heme biosynthesis in the cytosol, before biosynthesis is completed within mitochondria