Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.1.1.32: phosphoenolpyruvate carboxykinase (GTP)

This is an abbreviated version!
For detailed information about phosphoenolpyruvate carboxykinase (GTP), go to the full flat file.

Word Map on EC 4.1.1.32

Reaction

GTP
+
oxaloacetate
=
GDP
 +
phosphoenolpyruvate
 +
CO2

Synonyms

C4 phosphoenolpyruvate carboxykinase, carboxykinase, phosphopyruvate (guanosine triphosphate), CGI_10014916, CgPCK, GDP-linked PEP carboxykinase, GTP-dependent PEPCK-C, GTP-PEPCK, GTP/ITP: oxaloacetate carboxylase (transphosphorylating), GTP/ITP:oxaloacetate carboxylyase (transphosphorylating), GTP/ITP:oxaloacetatecarboxylase (transphosphorylating), GTP:oxaloacetate carboxy-lyase, oxaloacetate kinase (decarboxylating, GDP), P-enolpyruvate carboxykinase, PCK, PCK2, PDC-E2, PEP carboxykinase, PEP carboxylase, PEP-carboxykinase, PEPC, PEPCK, PEPCK-C, PEPCK-M, phosphoenolpyruvate carboxykinase, phosphoenolpyruvate carboxykinase (GTP), phosphoenolpyruvate carboxykinase, GTP-dependent, Phosphoenolpyruvate carboxylase, phosphoenolpyruvate carboxylase (GTP), phosphoenolpyruvic carboxykinase, phosphoenolpyruvic carboxykinase (GTP), phosphoenolpyruvic carboxykinase (inosine triphosphate), Phosphoenolpyruvic carboxylase, phosphoenolpyruvic carboxylase (GTP), phosphoenolpyruvic carboxylase (inosine triphosphate), phosphopyruvate carboxykinase, phosphopyruvate carboxylase, phosphopyruvate carboxylase (GTP)

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)

Reference

topprint

Reference on EC 4.1.1.32 - phosphoenolpyruvate carboxykinase (GTP)

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Barns, R.J.; Keech, D.B.
Sheep kidney phosphoenolpyruvate carboxylase. Purification and properties
Biochim. Biophys. Acta
276
284-296
1972
Ovis aries
Manually annotated by BRENDA team
Jo, J.S.; Ishihara, N.; Kikuchi, G.
Occurence and properties of four forms of phosphoenolpyruvate carboxykinase in the chicken liver
Arch. Biochem. Biophys.
160
246-254
1974
Gallus gallus
Manually annotated by BRENDA team
Ting, C.N.; Burgess, D.L.; Chamberlain, J.S.; Keith, T.P.; Falls, K.; Meisler, M.H.
Phosphoenolpyruvate carboxykinase (GTP): characterization of the human PCK1 gene and localization distal to MODY on chromosome 20
Genomics
16
698-706
1993
Homo sapiens
Manually annotated by BRENDA team
Colombo, G.; Carlson, G.M.; Lardy, H.A.
Phosphoenolpyruvate carboxykinase (guanosine triphosphate) from rat liver cytosol. Separation of homogenous forms of the enzyme with high and low activity by chromatography on agarose-hexane-guanosine triphosphate
Biochemistry
17
5321-5329
1978
Rattus norvegicus
Manually annotated by BRENDA team
Goto, Y.; Shimizu, J.; Okazaki, T.; Shukuya, R.
Purification and characterization of cytosol phosphoenolpyruvate carboxykinase from bullfrog (Rana catesbeiana) liver
J. Biochem.
86
71-78
1979
Lithobates catesbeianus
Manually annotated by BRENDA team
Goto, Y.; Shimizu, J.; Shukuya, R.
Purification and molecular characterization of mitochondrial phosphoenolpyruvate carboxykinase from bullfrog (Rana catesbeiana) liver
J. Biochem.
88
1239-1249
1980
Lithobates catesbeianus
Manually annotated by BRENDA team
Hebda, C.A.; Nowak, T.
The purification, characterization, and activation of phosphoenolpyruvate carboxykinase from chicken liver mitochondria
J. Biol. Chem.
257
5503-5514
1982
Gallus gallus
Manually annotated by BRENDA team
Miyatake, K.; Ito, T.; Kitaoka, S.
Subcellular location and some properties of phosphoenolpyruvate carboxykinase (PEPCK) in Euglena gracilis
Agric. Biol. Chem.
48
2139-2141
1984
Euglena gracilis
-
Manually annotated by BRENDA team
Rohrer, S.P.; Saz, H.J.; Nowak, T.
Purification and characteriation of phosphoenolpyruvate carboxykinase from the parasitic helminth Ascaris suum
J. Biol. Chem.
261
13049-13055
1986
Ascaris suum
Manually annotated by BRENDA team
Sato, A.; Suzuki, T.; Kochi, H.
Purification and characterization of cytosol-specific phosphoenolpyruvate carboxykinase from chicken liver
J. Biochem.
100
671-678
1986
Gallus gallus
Manually annotated by BRENDA team
Gallwitz, W.E.; Jacoby, G.H.; Ray, P.D.; Lambeth, D.O.
Purification and characterization of the isozymes of phosphoenolpyruvate carboxykinase from rabbit liver
Biochim. Biophys. Acta
964
36-45
1988
Oryctolagus cuniculus
Manually annotated by BRENDA team
Pönsgen-Schmidt, E.; Schneider, T.; Hammer, U.; Betz, A.
Comparison of phosphoenolpyruvate-carboxykinase from autotrophically and heterotrophically grown Euglena and its role during dark anaerobiosis
Plant Physiol.
86
457-462
1988
Euglena gracilis, Euglena gracilis 1224-5/9
Manually annotated by BRENDA team
Bentle, L.A.; Lardy, H.A.
Phosphoenolpyruvate carboxykinase ferroactivator. Purification and some properties
J. Biol. Chem.
252
1431-1440
1977
Rattus norvegicus
Manually annotated by BRENDA team
Vial, M.V.; Oelckers, K.B.; Rojas, M.C.; Simpfendörfer, R.W.
Purification, partial kinetic characterization and reactive sulfhydryl groups of the phosphoenolpyruvate carboxykinase from Perumytilus purpuratus adductor muscle
Comp. Biochem. Physiol. B
112
451-460
1995
Perumytilus purpuratus
-
Manually annotated by BRENDA team
Williams, C.P.; Postic, C.; Robin, D.; Robin, P.; Parrinello, J.; Shelton, K.; Printz, R.L.; Magnuson, M.A.; Granner, D.K.; Forest, C.; Chalkley, R.
Isolation and characterization of the mouse cytosolic phosphoenolpyruvate carboxykinase (GTP) gene: evidence for tissue-specific hypersensitive sites
Mol. Cell. Endocrinol.
148
67-77
1999
Mus musculus
Manually annotated by BRENDA team
Guidinger, P.F.; Nowak, T.
Analogs of oxalacetate as potential substrates for phosphoenolpyruvate carboxykinase
Arch. Biochem. Biophys.
178
131-141
1990
Gallus gallus
Manually annotated by BRENDA team
Johnson, W.V.; Kemp, J.R.; Anderson, P.M.
Purification and properties of mitochondrial phosphoenolpyruvate carboxykinase from liver of Squalus acanthias
Arch. Biochem. Biophys.
280
376-382
1990
Squalus acanthias
Manually annotated by BRENDA team
Lewis, C.T.; Haley, B.E.; Carlson, G.M.
Formation of an intramolecular cystine disulfide during the reaction of 8-azidoguanosine 5'-triphosphate with cytosolic phosphoenolpyruvate carboxykinase (GTP) causes inactivation without photolabeling
Biochemistry
28
9248-9255
1989
Rattus norvegicus
Manually annotated by BRENDA team
Dhe-Paganon, S.; Magrath, J.; Abeles, R.H.
Mechanism of mevalonate pyrophosphate decarboxylase: evidence for a carbocationic transition state
Biochemistry
33
13355-13362
1994
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Singla, S.K.
Nomenclature of phosphoenolpyruvate carboxykinase
Biochem. J.
248
623
1987
Metazoa
Manually annotated by BRENDA team
Knowles, S.E.; Gunn, J.M.; Reshef, L.; Hanson, R.W.; Ballard, F.J.
Properties of phosphoenolpyruvate carboxykinase (guanosine triphosphate) sythesized in hepatoma cells in the presence of amino acid analogues
Biochem. J.
146
585-593
1975
Rattus norvegicus
Manually annotated by BRENDA team
Bosch, F.; Hatzoglou, M.; Park, E.A.; Hanson, R.W.
Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells
J. Biol. Chem.
265
13677-13682
1990
Rattus norvegicus
Manually annotated by BRENDA team
Titheradge, M.A.; Picking, R.A.; Haynes, R.C.
Physiological concentration of 2-oxoglutarate regulate the activity of phosphoenolpyruvate carboxykinase in liver
Biochem. J.
285
767-771
1992
Rattus norvegicus
Manually annotated by BRENDA team
Ash, D.E.; Emig, F.A.; Chowdhury, S.A.; Satoh, Y.; Schramm, V.L.
Mammalian and avian liver phosphoenolpyruvate carboxykinase. Alternate substrates and inhibition by analogues of oxaloacetate
J. Biol. Chem.
265
7377-7384
1990
Gallus gallus, Rattus norvegicus
Manually annotated by BRENDA team
Jetten, M.S.M.; Sinskey, A.J.
Characterization of phosphoenolpyruvate carboxykinase from Corynebacterium glutamicum
FEMS Microbiol. Lett.
111
183-188
1993
Corynebacterium glutamicum
-
Manually annotated by BRENDA team
Harlocker, S.L.; Kapper, M.A.; Greenwalt, D.E.; Bishop, S.H.
Phosphoenolpyruvate carboxykinase from ribbed mussel gill tissue: reactivity with metal ions, kinetics, and action of 3-mercaptopicolinic acid
J. Exp. Zool.
257
285-298
1991
Modiolus demissus
-
Manually annotated by BRENDA team
Aich, S.; Imabayashi, F.; Delbaere, L.T.J.
Crystallization and preliminary X-ray crystallographic studies of phosphoenolpyruvate carboxykinase from Corynebacterium glutamicum
Acta Crystallogr. Sect. D
59
1640-1641
2003
Corynebacterium glutamicum (Q9AEM1)
Manually annotated by BRENDA team
Rios, S.E.; Nowak, T.
Role of cysteine 306 in the catalytic mechanism of Ascaris suum phosphoenolpyruvate carboxykinase
Arch. Biochem. Biophys.
404
25-37
2002
Ascaris suum
Manually annotated by BRENDA team
Zeitouni, N.; Eubank, D.W.; Lee, A.Q.; Oxford, M.G.; Freeman, T.L.; Mailliard, M.E.; Beale, E.G.
Phosphoenolpyruvate carboxykinase is induced in growth-arrested hepatoma cells
Biochem. Biophys. Res. Commun.
290
1513-1520
2002
Rattus norvegicus
Manually annotated by BRENDA team
Hlavaty, J.J.; Nowak, T.
Characterization of the second metal site on avian phosphoenolpyruvate carboxykinase
Biochemistry
39
1373-1388
2000
Gallus gallus
Manually annotated by BRENDA team
Holyoak, T.; Nowak, T.
Structural investigation of the binding of nucleotide to phosphoenolpyruvate carboxykinase by NMR
Biochemistry
40
11037-11047
2001
Gallus gallus, Rattus norvegicus
Manually annotated by BRENDA team
Foley, L.H.; Wang, P.; Dunten, P.; Ramsey, G.; Gubler, M.L.; Wertheimer, S.J.
Modified 3-alkyl-1,8-dibenzylxanthines as GTP-competitive inhibitors of phosphoenolpyruvate carboxykinase
Bioorg. Med. Chem. Lett.
13
3607-3610
2003
Homo sapiens
Manually annotated by BRENDA team
Mukhopadhyay, B.; Concar, E.M.; Wolfe, R.S.
A GTP-dependent vertebrate-type phosphoenolpyruvate carboxykinase from Mycobacterium smegmatis
J. Biol. Chem.
276
16137-16145
2001
Mycolicibacterium smegmatis (Q9AGJ6), Mycolicibacterium smegmatis mc(2)155 (Q9AGJ6)
Manually annotated by BRENDA team
Dunten, P.; Belunis, C.; Crowther, R.; Hollfelder, K.; Kammlott, U.; Levin, W.; Michel, H.; Ramsey, G.B.; Swain, A.; Weber, D.; Wertheimer, S.J.
Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site
J. Mol. Biol.
316
257-264
2002
Homo sapiens
Manually annotated by BRENDA team
Jabalquinto, A.M.; Laivenieks, M.; Cabezas, M.; Zeikus, J.G.; Cardemil, E.
The effect of active site mutations in the oxaloacetate decarboxylase and pyruvate kinase-like activities of Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase
J. Protein Chem.
21
443-445
2002
Anaerobiospirillum succiniciproducens
Manually annotated by BRENDA team
Agca, C.; Greenfield, R.B.; Hartwell, J.R.; Donkin, S.S.
Cloning and characterization of bovine cytosolic and mitochondrial PEPCK during transition to lactation
Physiol. Genomics
11
53-63
2002
Bos taurus
Manually annotated by BRENDA team
Aich, S.; Imabayashi, F.; Delbaere, L.T.J.
Expression, purification, and characterization of a bacterial GTP-dependent PEP carboxykinase
Protein Expr. Purif.
31
298-304
2003
Corynebacterium glutamicum
Manually annotated by BRENDA team
Holyoak, T.; Nowak, T.
pH Dependence of the reaction catalyzed by avian mitochondrial phosphoenolpyruvate carboxykinase
Biochemistry
43
7054-7065
2004
Gallus gallus
Manually annotated by BRENDA team
Cadoudal, T.; Leroyer, S.; Reis, A.F.; Tordjman, J.; Durant, S.; Fouque, F.; Collinet, M.; Quette, J.; Chauvet, G.; Beale, E.; Velho, G.; Antoine, B.; Benelli, C.; Forest, C.
Proposed involvement of adipocyte glyceroneogenesis and phosphoenolpyruvate carboxykinase in the metabolic syndrome
Biochimie
87
27-32
2005
Homo sapiens
Manually annotated by BRENDA team
Yerkovich, S.T.; Rigby, P.J.; Fournier, P.A.; Olynyk, J.K.; Yeoh, G.C.T.
Kupffer cell cytokines interleukin-1beta and interleukin-10 combine to inhibit phosphoenolpyruvate carboxykinase and gluconeogenesis in cultured hepatocytes
Int. J. Biochem. Cell Biol.
36
1462-1472
2004
Rattus norvegicus
Manually annotated by BRENDA team
Fukuda, W.; Fukui, T.; Atomi, H.; Imanaka, T.
First characterization of an archaeal GTP-dependent phosphoenolpyruvate carboxykinase from the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1
J. Bacteriol.
186
4620-4627
2004
Thermococcus kodakarensis (Q6F494)
Manually annotated by BRENDA team
Jin, J.Y.; DuBois, D.C.; Almon, R.R.; Jusko, W.J.
Receptor/gene-mediated pharmacodynamic effects of methylprednisolone on phosphoenolpyruvate carboxykinase regulation in rat liver
J. Pharmacol. Exp. Ther.
309
328-339
2004
Rattus norvegicus
Manually annotated by BRENDA team
Heled, Y.; Shapiro, Y.; Shani, Y.; Moran, D.S.; Langzam, L.; Barash, V.; Sampson, S.R.; Meyerovitch, J.
Physical exercise enhances hepatic insulin signaling and inhibits phosphoenolpyruvate carboxykinase activity in diabetes-prone Psammomys obesus
Metabolism
53
836-841
2004
Psammomys obesus
Manually annotated by BRENDA team
Holyoak, T.; Sullivan, S.M.; Nowak, T.
Structural insights into the mechanism of PEPCK catalysis
Biochemistry
45
8254-8263
2006
Gallus gallus (P21642)
Manually annotated by BRENDA team
Sullivan, S.M.; Holyoak, T.
Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid
Biochemistry
46
10078-10088
2007
Rattus norvegicus (P07379)
Manually annotated by BRENDA team
Case, C.L.; Mukhopadhyay, B.
Kinetic characterization of recombinant human cytosolic phosphoenolpyruvate carboxykinase with and without a His10-tag
Biochim. Biophys. Acta
1770
1576-1584
2007
Homo sapiens
Manually annotated by BRENDA team
Beale, E.G.; Harvey, B.J.; Forest, C.
PCK1 and PCK2 as candidate diabetes and obesity genes
Cell Biochem. Biophys.
48
89-95
2007
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Barry, R.C.; Young, M.J.; Stedman, K.M.; Dratz, E.A.
Proteomic mapping of the hyperthermophilic and acidophilic archaeon Sulfolobus solfataricus P2
Electrophoresis
27
2970-2983
2006
Saccharolobus solfataricus (Q97VS5), Saccharolobus solfataricus P2 (Q97VS5)
Manually annotated by BRENDA team
Case, C.L.; Concar, E.M.; Boswell, K.L.; Mukhopadhyay, B.
Roles of Asp75, Asp78, and Glu83 of GTP-dependent phosphoenolpyruvate carboxykinase from Mycobacterium smegmatis
J. Biol. Chem.
281
39262-39272
2006
Mycolicibacterium smegmatis (Q9AGJ6)
Manually annotated by BRENDA team
Hakimi, P.; Yang, J.; Casadesus, G.; Massillon, D.; Tolentino-Silva, F.; Nye, C.K.; Cabrera, M.E.; Hagen, D.R.; Utter, C.B.; Baghdy, Y.; Johnson, D.H.; Wilson, D.L.; Kirwan, J.P.; Kalhan, S.C.; Hanson, R.W.
Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse
J. Biol. Chem.
282
32844-32855
2007
Mus musculus
Manually annotated by BRENDA team
Le Moullac, G.; Bacca, H.; Huvet, A.; Moal, J.; Pouvreau, S.; Van Wormhoudt, A.
Transcriptional regulation of pyruvate kinase and phosphoenolpyruvate carboxykinase in the adductor muscle of the oyster Crassostrea gigas during prolonged hypoxia
J. Exp. Zool. A
307
371-382
2007
Crassostrea gigas, Crassostrea gigas (Q0KHB7)
Manually annotated by BRENDA team
Liu, K.; Ba, X.; Yu, J.; Li, J.; Wei, Q.; Han, G.; Li, G.; Cui, Y.
The phosphoenolpyruvate carboxykinase of Mycobacterium tuberculosis induces strong cell-mediated immune responses in mice
Mol. Cell. Biochem.
288
65-71
2006
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Castillo, D.; Sepulveda, C.; Cardemil, E.; Jabalquinto, A.M.
Functional evaluation of serine 252 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase
Biochimie
91
295-299
2008
Saccharomyces cerevisiae (P10963)
Manually annotated by BRENDA team
Dharmarajan, L.; Case, C.L.; Dunten, P.; Mukhopadhyay, B.
Tyr235 of human cytosolic phosphoenolpyruvate carboxykinase influences catalysis through an anion-quadrupole interaction with phosphoenolpyruvate carboxylate
FEBS J.
275
5810-5819
2008
Homo sapiens (P35558)
Manually annotated by BRENDA team
Aich, S.; Prasad, L.; Delbaere, L.T.
Structure of a GTP-dependent bacterial PEP-carboxykinase from Corynebacterium glutamicum
Int. J. Biochem. Cell Biol.
40
1597-1603
2008
Corynebacterium glutamicum (Q9AEM1), Corynebacterium glutamicum
Manually annotated by BRENDA team
Cadoudal, T.; Glorian, M.; Massias, A.; Fouque, F.; Forest, C.; Benelli, C.
Retinoids upregulate phosphoenolpyruvate carboxykinase and glyceroneogenesis in human and rodent adipocytes
J. Nutr.
138
1004-1009
2008
Rattus norvegicus, Homo sapiens (P35558), Homo sapiens
Manually annotated by BRENDA team
Chang, T.J.; Lee, W.J.; Chang, H.M.; Lee, K.C.; Chuang, L.M.
Expression of subcutaneous adipose tissue phosphoenolpyruvate carboxykinase correlates with body mass index in nondiabetic women
Metab. Clin. Exp.
57
367-372
2008
Homo sapiens
Manually annotated by BRENDA team
Christin, P.A.; Petitpierre, B.; Salamin, N.; Buechi, L.; Besnard, G.
Evolution of C(4) phosphoenolpyruvate carboxykinase in grasses, from genotype to phenotype
Mol. Biol. Evol.
26
357-365
2009
Digitaria sanguinalis, Sporobolus africanus, Sporobolus maritimus, Enteropogon prieurii, Megathyrsus maximus (Q7XAU8)
Manually annotated by BRENDA team
Ribeiro, L.C.; Chitto, A.L.; Mueller, A.P.; Rocha, J.K.; Castro da Silva, M.; Quincozes-Santos, A.; Nardin, P.; Rotta, L.N.; Ziegler, D.R.; Goncalves, C.A.; Da Silva, R.S.; Perry, M.L.; Gottfried, C.
Ketogenic diet-fed rats have increased fat mass and phosphoenolpyruvate carboxykinase activity
Mol. Nutr. Food Res.
52
1365-1371
2008
Rattus norvegicus
Manually annotated by BRENDA team
Lansard, M.; Panserat, S.; Seiliez, I.; Polakof, S.; Plagnes-Juan, E.; Geurden, I.; Medale, F.; Kaushik, S.; Corraze, G.; Skiba-Cassy, S.
Hepatic protein kinase B (Akt)-target of rapamycin (TOR)-signalling pathways and intermediary metabolism in rainbow trout (Oncorhynchus mykiss) are not significantly affected by feeding plant-based diets
Br. J. Nutr.
102
1564-1573
2009
Oncorhynchus mykiss (Q98T97)
Manually annotated by BRENDA team
Anand, P.; Murali, K.Y.; Tandon, V.; Murthy, P.S.; Chandra, R.
Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenolpyruvate carboxykinase, and GLUT4 translocation in experimental diabetic rats
Chem. Biol. Interact.
186
72-81
2010
Rattus norvegicus
Manually annotated by BRENDA team
Stark, R.; Pasquel, F.; Turcu, A.; Pongratz, R.L.; Roden, M.; Cline, G.W.; Shulman, G.I.; Kibbey, R.G.
Phosphoenolpyruvate cycling via mitochondrial phosphoenolpyruvate carboxykinase links anaplerosis and mitochondrial GTP with insulin secretion
J. Biol. Chem.
284
26578-26590
2009
Rattus norvegicus
Manually annotated by BRENDA team
Yang, J.; Kong, X.; Martins-Santos, M.E.; Aleman, G.; Chaco, E.; Liu, G.E.; Wu, S.Y.; Samols, D.; Hakimi, P.; Chiang, C.M.; Hanson, R.W.
Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha
J. Biol. Chem.
284
27042-27053
2009
Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Johnson, T.A.; Holyoak, T.
Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity
Biochemistry
49
5176-5187
2010
Rattus norvegicus (P07379)
Manually annotated by BRENDA team
Asanuma, N.; Kanada, K.; Arai, Y.; Yoshizawa, K.; Ichikawa, T.; Hino, T.
Molecular characterization and significance of phosphoenolpyruvate carboxykinase in a ruminal bacterium, Streptococcus bovis
J. Gen. Appl. Microbiol.
56
121-127
2010
Streptococcus equinus
Manually annotated by BRENDA team
Zhou, J.; Olson, D.G.; Argyros, D.A.; Deng, Y.; van Gulik, W.M.; van Dijken, J.P.; Lynd, L.R.
Atypical glycolysis in Clostridium thermocellum
Appl. Environ. Microbiol.
79
3000-3008
2013
Acetivibrio thermocellus, Acetivibrio thermocellus DSM 1313
Manually annotated by BRENDA team
Stark, R.; Kibbey, R.G.
The mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: has it been overlooked?
Biochim. Biophys. Acta
1840
1313-1330
2014
Gallus gallus
Manually annotated by BRENDA team
Stark, R.; Guebre-Egziabher, F.; Zhao, X.; Feriod, C.; Dong, J.; Alves, T.C.; Ioja, S.; Pongratz, R.L.; Bhanot, S.; Roden, M.; Cline, G.W.; Shulman, G.I.; Kibbey, R.G.
A role for mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) in the regulation of hepatic gluconeogenesis
J. Biol. Chem.
289
7257-7263
2014
Rattus norvegicus
Manually annotated by BRENDA team
Das, B.; Tandon, V.; Saxena, J.K.; Joshi, S.; Singh, A.R.
Purification and characterization of phosphoenolpyruvate carboxykinase from Raillietina echinobothrida, a cestode parasite of the domestic fowl
Parasitology
140
136-146
2013
Raillietina echinobothrida
Manually annotated by BRENDA team
Oda, H.; Okuda, Y.; Yoshida, Y.; Kimura, N.; Kakinuma, A.
Phenobarbital reduces blood glucose and gluconeogenesis through down-regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression in rats
Biochem. Biophys. Res. Commun.
466
306-311
2015
Rattus norvegicus
Manually annotated by BRENDA team
Lv, Z.; Qiu, L.; Wang, W.; Liu, Z.; Xue, Z.; Yu, Z.; Song, X.; Chen, H.; Wang, L.; Song, L.
A GTP-dependent phosphoenolpyruvate carboxykinase from Crassostrea gigas involved in immune recognition
Dev. Comp. Immunol.
77
318-329
2017
Crassostrea gigas (K1QEA6)
Manually annotated by BRENDA team
Valle, A.; Cabrera, G.; Cantero, D.; Bolivar, J.
Heterologous expression of the human phosphoenol pyruvate carboxykinase (hPEPCK-M) improves hydrogen and ethanol synthesis in the Escherichia coli dcuD mutant when grown in a glycerol-based medium
New Biotechnol.
35
1-12
2017
Homo sapiens (Q16822), Homo sapiens
Manually annotated by BRENDA team
Hidalgo, J.; Latorre, P.; Carrodeguas, J.A.; Velazquez-Campoy, A.; Sancho, J.; Lopez-Buesa, P.
Inhibition of pig phosphoenolpyruvate carboxykinase isoenzymes by 3-mercaptopicolinic acid and novel inhibitors
PLoS ONE
11
e0159002
2016
Sus scrofa
Manually annotated by BRENDA team