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4.1.1.25: tyrosine decarboxylase

This is an abbreviated version!
For detailed information about tyrosine decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.25

Reaction

L-tyrosine
=
tyramine
+
CO2

Synonyms

AADC, AtTYDC, Bradi2g51170, Decarboxylase, tyrosine, dTdc1, dTdc2, ELI5, L-(-)-Tyrosine apodecarboxylase, L-amino acid decarboxylase, L-Tyrosine decarboxylase, LbTDC, LOC100840315, MfnA protein, P0665A11.14, PcTYDC2, PF1159, PsTYDC1, PsTYDC2, TDC, tdcA, TYDC, TYDC/DODC, TYDC1, Tydc9, TYR decarboxylase, TyrDC, TyrDC-2, tyrosine decarboxylase, tyrosine decarboxylase-2, Tyrosine/Dopa decarboxylase, tyrosine/Dopa decarboxylase-1, tyrosine/Dopa decarboxylase-2, VwTYDC

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.25 tyrosine decarboxylase

General Stability

General Stability on EC 4.1.1.25 - tyrosine decarboxylase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
complete inactivation of purified TDC by freezing at -20°C, unstable during purification, washing of purified extract with sodium acetate buffer, pH 5, by ultracentrifugation results in complete loss of activity, partially restored by 0.2 mM pyridoxal 5’-phosphate
-
enzyme is stable during preparation, pyridoxal 5’-phosphate, glycerol, EDTA and 2-mercaptoethanol stabilize
L-tyrosine and pyridoxal 5’-phosphate stabilize
-
rapid loss of activity during purification
-
stabilized in presence of pyridoxal 5'-phosphate
unstable to freezing
-