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4.1.1.22: histidine decarboxylase

This is an abbreviated version!
For detailed information about histidine decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.22

Reaction

L-histidine
=
histamine
+
CO2

Synonyms

DCHS, Decarboxylase, histidine, HDC, HdcA, HisDCase, histamine-forming enzyme, L-Histidine decarboxylase, pyruvoyl-dependent decarboxylase, pyruvoyl-dependent histidine decarboxylase, TOM92

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.22 histidine decarboxylase

pH Range

pH Range on EC 4.1.1.22 - histidine decarboxylase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3.5 - 8
-
50% of maximal activity at pH 3.5
4
about 50% of maximum activity
4.2
83% of maximum activity
4.5 - 8.5
5.5 - 8
5.5 - 8.5
rapid loss of activity below pH 5.5
6 - 7.6
-
pH 6.0: about 50% of maximal activity, pH 7.6: about 40% of maximal activity
6.5
-
inducible enzyme
7
sharp decline in activiy above
7 - 9
8
18% of maximum activity