4.1.1.22: histidine decarboxylase
This is an abbreviated version!
For detailed information about histidine decarboxylase, go to the full flat file.
Word Map on EC 4.1.1.22
-
4.1.1.22
-
high-dose
-
mast
-
autologous
-
histaminergic
-
mucosa
-
stomach
-
gastrin
-
marrow
-
alpha-fluoromethylhistidine
-
hypothalamus
-
hematopoietic
-
enterochromaffin-like
-
cyclophosphamide
-
oxyntic
-
allergic
-
etoposide
-
biogenic
-
relapsed
-
chromogranin
-
thiotepa
-
basophil
-
decarboxylases
-
melphalan
-
cimetidine
-
tuberomammillary
-
carboplatin
-
pyrilamine
-
stem-cell
-
omeprazole
-
event-free
-
hypergastrinemia
-
h1-receptors
-
morganii
-
morganella
-
thioperamide
-
mucositis
-
carmustine
-
standard-dose
-
busulfan
-
pentagastrin
-
tourette
-
mepyramine
-
sleep-wake
-
fundic
-
mastocytoma
-
reinfusion
-
cell-deficient
-
drug development
-
medicine
-
aminergic
-
diagnostics
-
nutrition
-
chlorpheniramine
-
snell
- 4.1.1.22
-
high-dose
-
mast
-
autologous
-
histaminergic
- mucosa
- stomach
- gastrin
- marrow
- alpha-fluoromethylhistidine
- hypothalamus
-
hematopoietic
-
enterochromaffin-like
- cyclophosphamide
-
oxyntic
-
allergic
- etoposide
-
biogenic
-
relapsed
-
chromogranin
-
thiotepa
-
basophil
- decarboxylases
- melphalan
- cimetidine
-
tuberomammillary
- carboplatin
-
pyrilamine
-
stem-cell
- omeprazole
-
event-free
-
hypergastrinemia
-
h1-receptors
- morganii
- morganella
- thioperamide
- mucositis
- carmustine
-
standard-dose
-
busulfan
- pentagastrin
- tourette
-
mepyramine
-
sleep-wake
- fundic
- mastocytoma
-
reinfusion
-
cell-deficient
- drug development
- medicine
-
aminergic
- diagnostics
- nutrition
-
chlorpheniramine
-
snell
Reaction
Synonyms
DCHS, Decarboxylase, histidine, HDC, HdcA, HisDCase, histamine-forming enzyme, L-Histidine decarboxylase, pyruvoyl-dependent decarboxylase, pyruvoyl-dependent histidine decarboxylase, TOM92
ECTree
Advanced search results
Source Tissue
Source Tissue on EC 4.1.1.22 - histidine decarboxylase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
-
the posterodorsal medial amygdala has high levels of histidine decarboxylase
-
HDC expression is significantly increased in carcinoma cells
-
in the acute phase of infection of mice infected with Leishmania major, detected in both strains the resistant C57BL/6 and the susceptible BALB/c. Only susceptible mice known to be unable to control parasite dissemination show induction of histidine decarboxylase in their distant periaortic lymph nodes as well. During the chronic phase of infection only the heavily parasitized organs of BALB/c mice show high expression of histidine decarboxylase gene
human oxyntic mucosa contains four major types of neuroendocrine cells: ECL, ghrelin, serotonin and somatostatin cells
-
histidine decarboxylase is induced upon infiltration of polymorphonuclear leukocytes into mouse peritoneal cavity. Histamine is synthesized by the enzyme attached to the granule membrane of polymorphonuclear leukocytes
additional information
-
of osteoarthritic cartilage. Histidine decarboxylase is localized within chondrocytes of the superficial layer of nearly all the osteoarthritis specimen examined, with little or no immunostaining in the intermediate or deep zones. Production of histamine and histidine decarboxylase in specimen of osteoarthritic cartilage respresents three grades of clinical severity
-
high levels of HDC protein are also found in the striatum
the tumours are classified based on clinico-pathological criteria
highly expressed in the hypothalamic infundibulum, the cells containing HDC mRNA are localized in the medial mammillary nucleus of the hypothalamic infundibulum
-
hypertrophic and hyperplastic, Increase in histidine decarboxylase activity in regenerative growth of renal epithelium can result from activation of translation or increased half-life, i.e. slower degradation of the enzyme protein, or both
pregnancy associated elevation of histidine decarboxylase activity is successfully affected by enzyme antisense oligonucleotide treatment, inducing short-term histamine deficiency
-
neoplastic mast cells in patients with systemic mastocytosis, including MC leukemia and MC sarcoma, expression in mast cells of different maturation stage, immunohistochemic detection and quantitative expression analysis
-
during the chronic phase of infection elevated levels of histidine decarboxylase, possibly of mast cell origin, are associated with Th2-dominated responses and serious disease development
neurons of the tuberomammillary nucleus of the posterior hypothalamus
-
neurons of the tuberomammillary nucleus of the posterior hypothalamus
-
-
differential activity of HDC in normal and pre-eclamptic placentae, overview
masseter, pectoralis, and quadriceps femoris, in cells in the endomysium and around blood vessels, and also in some muscle fibers
-
masseter, pectoralis, and quadriceps femoris, in cells in the endomysium and around blood vessels, and also in some muscle fibers
-
histidine decarboxylase (HDC) expression in healthy and neoplastic gastric neuroendocrine cells in relationship to the main histamine metabolite, immunoreactive localization study, overview
additional information
-
histidine decarboxylase (HDC) expression in healthy and neoplastic gastric neuroendocrine cells in relationship to the main histamine metabolite, immunoreactive localization study, overview
additional information
human HDC expression is mainly detected in hypothalamus, lung and stomach in comparison with the rest of the tissues
additional information
-
human HDC expression is mainly detected in hypothalamus, lung and stomach in comparison with the rest of the tissues
additional information
keratinocytes express abundant HDC protein, and the levels increase in atopic skin
additional information
-
keratinocytes express abundant HDC protein, and the levels increase in atopic skin
additional information
immunostaining of HDC in murine skeletal muscle tissues, overview
additional information
-
immunostaining of HDC in murine skeletal muscle tissues, overview
-
additional information
immunolocalization of histamine, with rabbit anti-L-histidine decarboxylase (HDC) antiserum, within the tuberomammillary nucleus is validated using carbodiimide. Rapid eye movement sleep deprivation (REM-SD) increases immunoreactive L-histidine decarboxylase by day 5, and it remains elevated in both dorsal and ventral aspects of the tuberomammillary complex
additional information
-
immunolocalization of histamine, with rabbit anti-L-histidine decarboxylase (HDC) antiserum, within the tuberomammillary nucleus is validated using carbodiimide. Rapid eye movement sleep deprivation (REM-SD) increases immunoreactive L-histidine decarboxylase by day 5, and it remains elevated in both dorsal and ventral aspects of the tuberomammillary complex
-