4.1.1.22: histidine decarboxylase

This is an abbreviated version!
For detailed information about histidine decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.22

4.1.1.22

high-dose

mast

autologous

histaminergic

mucosa

stomach

gastrin

marrow

alpha-fluoromethylhistidine

hypothalamus

hematopoietic

enterochromaffin-like

cyclophosphamide

oxyntic

allergic

etoposide

biogenic

relapsed

chromogranin

thiotepa

basophil

decarboxylases

melphalan

cimetidine

tuberomammillary

carboplatin

pyrilamine

stem-cell

omeprazole

event-free

hypergastrinemia

h1-receptors

morganii

morganella

thioperamide

mucositis

carmustine

standard-dose

busulfan

pentagastrin

tourette

mepyramine

sleep-wake

fundic

mastocytoma

reinfusion

cell-deficient

drug development

medicine

aminergic

diagnostics

nutrition

chlorpheniramine

snell

Reaction

Synonyms

DCHS, Decarboxylase, histidine, HDC, HdcA, HisDCase, histamine-forming enzyme, L-Histidine decarboxylase, pyruvoyl-dependent decarboxylase, pyruvoyl-dependent histidine decarboxylase, TOM92

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.1 Carboxy-lyases

4.1.1.22 histidine decarboxylase

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Results	in table
29	Activating Compound
832	AA Sequence
9	Application
1	CAS Registry Number
62	Cloned(Commentary)
88	Cofactor
8	Crystallization (Commentary)
2494	Disease/ Diagnostics
13	Expression
14	General Information
3	General Stability
1	IC50 Value
137	Inhibitors
5	kcat/KM [mM/s]
6	Ki Value [mM]
36	KM Value [mM]
10	Localization
11	Metals/Ions
49	Molecular Weight [Da]
87	Natural Substrates/ Products (Substrates)
255	Organism
6	Pathway
48	PDB ID
40	pH Optimum
17	pH Range
4	pH Stability
1	pI Value
10	Posttranslational Modification
71	Protein Variants
35	Purification (Commentary)
3	Reaction
1	Reaction Type
235	Reference
145	Source Tissue
27	Specific Activity [micromol/min/mg]
12	Storage Stability
236	Substrates and Products (Substrate)
61	Subunits
146	Synonyms
1	Systematic Name
23	Temperature Optimum [°C]
9	Temperature Range [°C]
21	Temperature Stability [°C]
5	Turnover Number [1/s]

Purification

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Purification on EC 4.1.1.22 - histidine decarboxylase

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10 entries

ammonium sulfate, anion-exchange column, hydroxyapatite column

Tetragenococcus muriaticus

651607

His-Trap-FF crude chelating affinity chromatography

Staphylococcus capitis

A9IZZ1

692805

native enzyme by ammonium sulfate fractionation, gel filtration, and anion exchange chromatography, to homogeneity

Klebsiella aerogenes

749155

Ni2+-NTA column chromatography

Streptococcus thermophilus

716264

partial

2 entries

partial, 3 enzyme forms: 1, 2 and 3

Rattus norvegicus

4147

partially purified 53000 Da HDC

Mus musculus

652237

phenyl-Sepharose column chromatography, DEAE column chromatography, and hydroxyapatite column chromatography

recombinant HDC

recombinant His-tagged enzyme

Rattus norvegicus

663937

recombinant His-tagged enzyme from Escherichia coli by cobalt affinity chromatography

4 entries

recombinant protein

Rattus norvegicus

663930

separation of unmodified alpha and beta subunits and for reconstitution of fully active histidine decarboxylase

Lactobacillus sp.

4138