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4.1.1.2: oxalate decarboxylase

This is an abbreviated version!
For detailed information about oxalate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.2

Reaction

oxalate
=
formate
 +
CO2

Synonyms

AnODC, AtuOXDC, Decarboxylase, oxalate, FvOXDC, More, ODC, ODC B, ODC C, ODC E, ODC F, odc2, oxalate carboxy-lyase, oxalate-decarboxylase, oxazyme, OXD, OXDC, OxDc-CLEC, OxDcase, OxdD, pBy, TOXDC, YoaN, YvrK

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.2 oxalate decarboxylase

Inhibitors

Inhibitors on EC 4.1.1.2 - oxalate decarboxylase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-oxoglutaric acid
-
about 82% residual activity at 25 mM
Biomimetic monochlorotriazinyl dyes
-
bearing a mercaptopyruvate at the terminal biomimetic moiety, competitive against oxalate
-
Chlorite
-
26% residual activity at 8.0 mM
Citric acid
-
about 77% residual activity at 25 mM
Co2+
-
complete inhibition at 10 mM
Dithionite
formic acid
-
75% residual activity at 20 mM
Fumaric acid
-
about 73% residual activity at 25 mM
glycolic acid
-
88% residual activity at 20 mM
hydrogen peroxide
-
5% residual activity at 20 mM
hydroxylamine
Maleic acid
-
about 69% residual activity at 25 mM
malonic acid
-
about 68% residual activity at 25 mM
NaBr
-
about 71% residual activity at 50 mM
NaCl
-
about 98% residual activity at 50 mM
NaF
-
about 68% residual activity at 50 mM
NaI
-
about 82% residual activity at 50 mM
nitric oxide
-
reversible inhibition under dioxygen-depleted conditions with 100fold reduction of activity in the presence of 0.05 mM nitric oxide. At 12 min, air is re-introduced, resulting in the restoration of full OxDC catalytic activity, albeit after a time lag of approximately 5 min
oxalate
substrate inhibition
oxaloacetic acid
-
about 68% residual activity at 25 mM
phosphate
-
competitive
Phthalic acid
-
about 97% residual activity at 25 mM
Sodium dithionite
-
about 75% residual activity at 5 mM
sodium sulfite
-
about 60% residual activity at 5 mM
succinic acid
-
about 77% residual activity at 25 mM
sulfite
-
complete inhibition at 1.0 mM
Surface-active ionic substances
-
anionic or cationic
-
additional information
-
up to 4 mM chlorate has no inhibitory effect on oxalate decarboxylase
-