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4.1.1.19: arginine decarboxylase

This is an abbreviated version!
For detailed information about arginine decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.19

Reaction

L-arginine
=
agmatine
 +
CO2

Synonyms

AaxB, AaxB protein, acid-induced biodegradative arginine decarboxylase, ADC, ADC 1, ADC 2, ADC1, ADC2, AdiA, ARGDC, arginine decarboxlase 2, arginine decarboxylase, arginine decarboxylase2, arginine:agmatine exchange system, ATADC1, AtADC2, AtDC2, bADC, Biosynthetic arginine decarboxylase, biosynthetic arginine decarboxylase 1, biosynthetic arginine decarboxylase 2, ClADC, CPn1032 homolog, dADC, Decarboxylase, arginine, HP0422, HVO_1958, L-Arginine decarboxylase, More, NtADC1, NtADC2, PaADC1, PaADC2, PBCV-1 DC, PdaD, PpADC, protein SSO0536, PtADC, PvlArgDC, pyruvoyl-dependent arginine decarboxylase, pyruvoyl-dependent arginine decraboxylase, slr0662, slr1312, SPE1, SPE2, SpeA, speA1, speA2, StADC, Synthetic arginine decarboxylase, Tk-PdaD, TK0149

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.19 arginine decarboxylase

Expression

Expression on EC 4.1.1.19 - arginine decarboxylase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
0.005 mlM MeHg, EtHg, PhHg and HgCl2 increase the protein expression by 1.23, 1.06, 1.45, and 1.33fold, respectively
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ADC is active early during pollen hydration and germination in vitro, ADC activity is activated during pollen germination
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ADC protein and transcript are increasingly expressed at early stages of hop internode culture (12 h). Protein and transcript continue accumulating until organogenic nodule formation after 28 days, decreasing thereafter
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after exposure to 0.2 mM methyl jasmonate for 6 h, the intensity of the Adc mRNA signal fell by approximately 90%, and after 24 h of treatment it returns to near the original level
arginine decarboxylase has been shown to be upregulated from the macrophage-like cell line RAW-264.7 in response to lipopolysaccharides and cytokines resulting in more intracellular agmatine. Bacterial agmatine secretion after infection with Pseudomonas aeruginosa is evident in changes in the inflammatory phenotype including increased total cell count
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as opposed to wild-type plants, bacterial infection with Pseudomonas viridiflava strain Pvalb8 increases ADC2 expression and ADC activity in adc1 mutants, which can counterbalance the lack of ADC1. High osmolarity, drought, salinity and wounding induce ADC2 expression. In non-inoculated adc mutants, the lack of each ADC isoform has no effect on expression of the other isoforms. Infection of the adc2-3 mutant also caused a several fold increase in ADC1 expression at both times after inoculation
bacterial infection induces putrescine accumulation and ADC1 expression in wild-type plants, but pathogen-induced putrescine accumulation is blocked in adc1 mutant. In non-inoculated adc mutants, the lack of each ADC isoform has no effect on expression of the other isoforms. Infection of the adc2-3 mutant also causes a several fold increase in ADC1 expression at both times after inoculation
enzyme activity and agmatine levels in human sputum peak during cystic fibrosis illness, decrease with treatment, and is positively correlated with inflammatory cytokines
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enzyme mRNA and protein expression are acutely induced by acid stress. Transcriptional factor Fur regulates the expression of the speA gene in the acid response
FcWRKY70, a WRKY protein of Fortunella crassifolia, functions in drought tolerance and modulates putrescine synthesis by regulating arginine decarboxylase gene, the promoter region of FcADC contains two W-box elements, which interacts with FcWRKY70
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FcWRKY70, a WRKY protein of Fortunella crassifolia, functions in drought tolerance and modulates putrescine synthesis by regulating arginine decarboxylase gene. Overexpression of FcWRKY70 in Citrus lemon confers enhances tolerance to dehydration and drought stresses. Transgenic lemon exhibits higher expression levels of ADC and accumulats larger amount of putrescine in comparison with the wild-type
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FcWRKY70, a WRKY protein of Fortunella crassifolia, functions in drought tolerance and modulates putrescine synthesis by regulating arginine decarboxylase gene. Overexpression of FcWRKY70 in Nicotiana nudicaulis confers enhanced tolerance to dehydration and drought stresses. Transgenic lemon exhibits higher expression levels of ADC and accumulats larger amount of putrescine in comparison with the wild-type
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ICE1 (inducer of CBF expression 1) encodes a MYC-like basic helix-loop-helix transcription factor that acts as a central regulator of cold response. Yeast two-hybrid screening reveals that 21 proteins belong to the PtrICE1 interactome, in which PtADC (arginine decarboxylase) is confirmed as a bona fide protein interacting with PtrICE1 (nuclear localization). Transcript levels of ADC genes in the transgenic lines are slightly elevated under normal growth conditions but substantially increased under cold conditions, consistent with changes in free polyamine levels
in enteroinvasive strains the presence of CadC reduces the expression of the arginine decarboxylase encoding gene adiA
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mercury compounds inhibits the enzyme activity but induce the enzyme expression in PC12 cells. The results indicate that ADC inhibition in PC12 cells by the four Hg compounds is due to the loss of enzyme activity, not protein level
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no effect of NaCl at 0.5 M on the expression of adc1
no effect of NaCl at 0.5 M on the expression of adc2
relative expression level for arginine decarboxylase related gene is significantly higher for acid adapted cells
salicylic acid treatment results in a significant increase in the expression of ADC after 3 h
salt stress clearly results in an increased steady-state transcript accumulation even though the specific activity shows no apparent change
steady-state accumulation of arginine decarboxylase transcripts and its specific activity are unaffected by dark incubation
transcript levels are up-regulated by low temperature and dehydration
transcription factor ICE1 from Poncirus trifoliata, PtICE1 (inducer of CBF expression 1) is a MYC-like basic helix-loop-helix transcription factor that acts as a central regulator of cold response. Transcript levels of ADC genes in the transgenic Nicotiana tabacum lines are slightly elevated under normal growth condition but substantially increased under cold conditions, consistent with changes in free polyamine levels
transcription factor ICE1 from Poncirus trifoliata, PtICE1 (inducer of CBF expression 1) is a MYC-like basic helix-loop-helix transcription factor that acts as a central regulator of cold response. Transcript levels of ADC genes in the transgenic Nicotiana tabacum lines are slightly elevated under normal growth condition but substantially increased under cold conditions, consistent with changes in free polyamine levels. Expression patterns of NtADC1 and NtADC2 in wild-type and transgenic tobacco lines before and after cold stress, overview
transcription factor ICE1 from Poncirus trifoliata, PtICE1 (inducer of CBF expression 1) is a MYC-like basic helix-loop-helix transcription factor that acts as a central regulator of cold response. Transcript levels of Citrus limon ADC gene in the transgenic lines are slightly elevated under normal growth condition but substantially increased under cold conditions, consistent with changes in free polyamine levels. Expression patterns of ClADC in lemon wild-type and transgenic lines before and after 5 h of cold stress, overview
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