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4.1.1.103: gamma-resorcylate decarboxylase

This is an abbreviated version!
For detailed information about gamma-resorcylate decarboxylase, go to the full flat file.

Reaction

2,6-dihydroxybenzoate
=
1,3-dihydroxybenzene
+
CO2

Synonyms

graF, Rdc, TsdA

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.103 gamma-resorcylate decarboxylase

Metals Ions

Metals Ions on EC 4.1.1.103 - gamma-resorcylate decarboxylase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
1 mM, 132% of initial activity for decarboxylation reaction, 106% of initial activity for carboxylation reaction
Mn2+
presence of Mn2+ in the active site, data from crystal structure
Zn2+
the native enzyme possesses one Zn2+ ion liganded by Glu8, His10, His164, Asp287, and a water molecule at the active site center