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4.1.1.1: pyruvate decarboxylase

This is an abbreviated version!
For detailed information about pyruvate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.1

Reaction

a 2-oxo carboxylate
=
an aldehyde
 +
CO2

Synonyms

2-oxo acid carboxylyase, 8-10 nm cytoplasmic filament-associated protein, acetohydroxyacid synthase, AHAS, alpha-Carboxylase, alpha-Keto acid carboxylase, ANC27, bifunctional pyruvate decarboxylase/pyruvate ferredoxin oxidoreductase, Decarboxylase, pyruvate, GPDC1, IFPL730, KivD, KlPDC, KviD, NcPDC, P59NC, PDC, PDC I, PDC II, PDC1, Pdc1p, PDC2, PDC3, PDC4, Pdc5, Pdc5p, Pdc6, PDCS.c., PDCZ.m., PDHC, POR, pyruvamide-activated yeast pyruvate decarboxylase, pyruvate decarboxylase, pyruvate decarboxylase 1, pyruvate decarboxylase 2, pyruvate decarboxylase complex, Pyruvic decarboxylase, R-selective pyruvate decarboxylase, SCPDC, scpdc1, ScPDC5, TTHA1213, yeast pyruvate decarboxylase, YPDC, ZbPDC, ZmPDC

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.1 pyruvate decarboxylase

Molecular Weight

Molecular Weight on EC 4.1.1.1 - pyruvate decarboxylase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
12000
2 * 12000 + 2 * 26000 + 2 * 35000 + 2 * 46000, SDS-PAGE
120000 - 128000
dimeric enzyme form, native PAGE
13000
Q56317; 05650; Q56316; O05651
1 * 46000 plus 1 * 35000 plus 1 * 23000 plus 1 * 13000, SDS-PAGE
14000
1 * 45000 plus 1 * 35000 plus 1 * 22000 plus 1 * 14000, SDS-PAGE
150000
gel filtration
156000
Q56317; 05650; Q56316; O05651
gel filtration
200000
209000
-
gel filtration
210000
-
gel filtration
219700
-
gel filtration
22000
1 * 45000 plus 1 * 35000 plus 1 * 22000 plus 1 * 14000, SDS-PAGE
220000 - 240000
-
gel filtration
23000
Q56317; 05650; Q56316; O05651
1 * 46000 plus 1 * 35000 plus 1 * 23000 plus 1 * 13000, SDS-PAGE
235000
recombinant PDC, pH 6.5, gel filtration
240000
244000
active enzyme, gel filtration
26000
2 * 12000 + 2 * 26000 + 2 * 35000 + 2 * 46000, SDS-PAGE
272000
tetrameric enzyme form, native PAGE
35000
390000
-
gel filtration
39800
-
1 * 39800 + 1 * 41700, the dimeric pyruvate decarboxylase is a component of the multienzyme complex pyruvate dehydrogenase, SDS-PAGE
41700
-
1 * 39800 + 1 * 41700, the dimeric pyruvate decarboxylase is a component of the multienzyme complex pyruvate dehydrogenase, SDS-PAGE
45000
1 * 45000 plus 1 * 35000 plus 1 * 22000 plus 1 * 14000, SDS-PAGE
46000
56500
-
4 * 56500, SDS-PAGE
57000
-
4 * 57000, SDS-PAGE
58000
58700
2 * 58700, SDS-PAGE, 2 * 62000, calculated, both isoform PDC I and PDC II
58873
x * 58873, anhydrous molecular mass, calculated from the amino acid sequence
59000
59200
59400
2 * 59400, calculated from amino acid sequence
60746
-
4 * 60746, SDS-PAGE
60800
61000
61320
-
x * 60000, SDS-PAGE, x * 61320, mass spectrometry, x * 61468, calculated from the nucleotide sequence
61468
-
x * 60000, SDS-PAGE, x * 61320, mass spectrometry, x * 61468, calculated from the nucleotide sequence
61486
-
x * 60000, about, SDS-PAGE, x * 61486, calculated from the amino acid sequence
61500
-
4 * 61500, mass spectrometry, SDS-PAGE, 4 * 61821, calculated from the amino acid sequence
61600
alpha4, 4 * 61000, SDS-PAGE, 4 * 61600, amino acid sequence
61821
-
4 * 61500, mass spectrometry, SDS-PAGE, 4 * 61821, calculated from the amino acid sequence
62000
63000
-
x * 63000, SDS-PAGE
64000
x * 64000, alpha-subunit + x * 62000, beta-subunit
65300
x * 65300, calculated
66000