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4.1.1.1: pyruvate decarboxylase

This is an abbreviated version!
For detailed information about pyruvate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.1

Reaction

a 2-oxo carboxylate
=
an aldehyde
 +
CO2

Synonyms

2-oxo acid carboxylyase, 8-10 nm cytoplasmic filament-associated protein, acetohydroxyacid synthase, AHAS, alpha-Carboxylase, alpha-Keto acid carboxylase, ANC27, bifunctional pyruvate decarboxylase/pyruvate ferredoxin oxidoreductase, Decarboxylase, pyruvate, GPDC1, IFPL730, KivD, KlPDC, KviD, NcPDC, P59NC, PDC, PDC I, PDC II, PDC1, Pdc1p, PDC2, PDC3, PDC4, Pdc5, Pdc5p, Pdc6, PDCS.c., PDCZ.m., PDHC, POR, pyruvamide-activated yeast pyruvate decarboxylase, pyruvate decarboxylase, pyruvate decarboxylase 1, pyruvate decarboxylase 2, pyruvate decarboxylase complex, Pyruvic decarboxylase, R-selective pyruvate decarboxylase, SCPDC, scpdc1, ScPDC5, TTHA1213, yeast pyruvate decarboxylase, YPDC, ZbPDC, ZmPDC

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.1 pyruvate decarboxylase

Expression

Expression on EC 4.1.1.1 - pyruvate decarboxylase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
alpha-ketoisovalerate decarboxylase (kivD), BCAA-specific aminotransferase (bcaT) and C-S lyase (yjtE) gene expressions increase markedly by both isoleucine and valine starvation
expression of both PDC1 and PDC2 is strongly upregulated under low oxygen
for PDC, the level of transcripts remain quantitatively constant in all fruit maturity stages
gene expression is not induced by 2,4-dichlorophenoxyacetic acid treatment
gene PDC3 is not regulated by low-oxygen stress
gene PDC4 is not regulated by low-oxygen stress
isoform PDC1, PDC2 and PDC3 show striking expressional responses in leaves and bark to drought, low temperature and high temperature stresses
isoleucine starvation increases 4fold the Kivd activity compared to cells grown in chemically defined medium with casitone as nitrogen source. Regulation of expression is at the transcription level, probably mediated by CodY
PDC4 expression is down-regulated as the degree of tapping panel dryness increases
PDC4 expression is induced by tapping, with transcripts showing a rapid increase (150fold) during the first seven tappings, and PDC4 shows a rapid increase in expression after wounding treatment
the expression of both isoforms PDC1 and PDC2 is strongly up-regulated under low oxygen
the expression of isoform PDC1 is enhanced by D-glucose
waterlogging, NaCl, and heat can induce the expression of isoform PDC2
-