3.9.1.3: phosphohistidine phosphatase
This is an abbreviated version!
For detailed information about phosphohistidine phosphatase, go to the full flat file.
Word Map on EC 3.9.1.3
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Synonyms
14 kDa phosphohistidine phosphatase, 14-kDa phosphohistidine phosphatase, 16 kDa protein histidine phosphatase, histidine protein phosphatase, LHPP, PGAM5, phospho-histidine phosphatase, phosphohistidine phosphatase, phosphohistidine phosphatase 1, phosphohistidine phosphatase I, phosphopolyhistidine phosphatase, PHP, PHP14, PHPT-1, PHPT1, PHPTI, PP1, PP2A, protein histidine phosphatase, protein histidine phosphatase 1, protein-histidine phosphatase, SixA
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Source Tissue on EC 3.9.1.3 - phosphohistidine phosphatase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
colocalization of the enzyme (PHP14) with Arp3 and F-actin at the leading edge of migrating cells. PHP14 is recruited to the actin remodeling sites in parallel with Arp3 during lamellipodia formation
enzyme (PHP14) expression is upregulated in fibrotic liver and mainly in hepatic stellate cells
in patients with hepatocellular carcinoma, low expression of LHPP correlated with increased tumour severity and reduced overall survival
colocalization of the enzyme (PHP14) with Arp3 and F-actin at the leading edge of migrating cells. PHP14 is recruited to the actin remodeling sites in parallel with Arp3 during lamellipodia formation
enzyme (PHP14) expression is upregulated in fibrotic liver and mainly in hepatic stellate cells
hepatic expression of LHPP in the hepatocellular carcinoma mouse model reduces tumour burden and prevents the loss of liver function
