3.8.1.6: 4-chlorobenzoate dehalogenase
This is an abbreviated version!
For detailed information about 4-chlorobenzoate dehalogenase, go to the full flat file.
Word Map on EC 3.8.1.6
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3.8.1.6
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4-hydroxybenzoate
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dehalogenation
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cosmid
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chlorinated
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mgatp
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coa
- 3.8.1.6
- 4-hydroxybenzoate
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dehalogenation
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cosmid
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chlorinated
- mgatp
- coa
Reaction
Synonyms
FcbB
ECTree
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Engineering
Engineering on EC 3.8.1.6 - 4-chlorobenzoate dehalogenase
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A154R
84% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 57% of wild-type activity with 4-chlorobenzoate
A154S
84% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 47% of wild-type activity with 4-chlorobenzoate
D155Y
no decrease in glutathione S-transferase actvitiy, affected in thermostability, 96% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 95% of wild-type activity with 4-chlorobenzoate
L158P
56% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 50% of wild-type activity with 4-chlorobenzoate
S152G
4% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 3% of wild-type activity with 4-chlorobenzoate
S152I
53% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 156% of wild-type activity with 4-chlorobenzoate
V153I
56% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 52% of wild-type activity with 4-chlorobenzoate
V153R
4% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 39% of wild-type activity with 4-chlorobenzoate
Y157W
49% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 59% of wild-type activity with 4-chlorobenzoate
L158P
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56% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 50% of wild-type activity with 4-chlorobenzoate
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S152G
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4% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 3% of wild-type activity with 4-chlorobenzoate
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S152I
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53% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 156% of wild-type activity with 4-chlorobenzoate
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V153I
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56% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 52% of wild-type activity with 4-chlorobenzoate
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V153R
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4% of wild-type activity with 1-chloro-2,4-dinitrobenzene, 39% of wild-type activity with 4-chlorobenzoate
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