3.8.1.5: haloalkane dehalogenase
This is an abbreviated version!
For detailed information about haloalkane dehalogenase, go to the full flat file.
Word Map on EC 3.8.1.5
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3.8.1.5
-
xanthobacter
-
autotrophicus
-
dehalogenation
-
1,2-dichloroethane
-
halide
-
carbon-halogen
-
1,2-dibromoethane
-
sphingomonas
-
paucimobilis
-
1,2,3-trichloropropane
-
synthesis
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hexachlorocyclohexane
-
rhodochrous
-
sphingobium
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environmental protection
-
alkyl-enzyme
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haloacid
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1-chlorobutane
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2-chloroethanol
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ncimb
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chloroalkane
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dehydrochlorinase
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epichlorohydrine
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gamma-hexachlorocyclohexane
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halotag
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biotechnology
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alpha/beta-hydrolase
-
haloalcohols
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agriculture
-
halide-binding
-
degradation
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industry
- 3.8.1.5
- xanthobacter
- autotrophicus
-
dehalogenation
- 1,2-dichloroethane
- halide
-
carbon-halogen
- 1,2-dibromoethane
- sphingomonas
- paucimobilis
- 1,2,3-trichloropropane
- synthesis
- hexachlorocyclohexane
- rhodochrous
- sphingobium
- environmental protection
-
alkyl-enzyme
-
haloacid
- 1-chlorobutane
- 2-chloroethanol
-
ncimb
-
chloroalkane
- dehydrochlorinase
- epichlorohydrine
- gamma-hexachlorocyclohexane
-
halotag
- biotechnology
-
alpha/beta-hydrolase
- haloalcohols
- agriculture
-
halide-binding
- degradation
- industry
Reaction
Synonyms
1,3,4,6,-tetrachloro-1,4-cyclohexadiene halidohydrolase, 1-chlorohexane halidohydrolase, 1-haloalkane dehalogenase, DadB, DatA, DbeA, DbjA, DccA, DhaA, DhaA31, DhaB, DhaC, DhAf, DhlA, DhmA, DmaA, dmbA, DmbB, DmbC, dmlA, DmmA, DmrA, DmrB, DmsA, DmtA, DmxA, DpcA, DppA, DrbA, DsaA, DspA, EC 3.8.1.1, eHLD-B, eHLD-C, haloalkane dehalogenase, haloalkane dehalogenase LinB, HanR, HLD, HLD-I, LinB, LinBMI, LinBUT, metallo-haloalkane dehalogenase, protein XP_504164, Rv2579, Ylehd
ECTree
3.8.1.5 haloalkane dehalogenaseAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 3.8.1.5 - haloalkane dehalogenase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1,2,3-trichloropropane + H2O
(RS)-2,3-dichloropropan-1-ol + chloride
-
-
-
-
?
1,2,3-trichloropropane + H2O
2,3-dichlorpropane-1-ol + chloride
-
-
-
ir
1,3,4,6-tetrachloro-1,4,cyclohexadiene + 2 H2O
2,5-dichloro-2,5-cyclohexadiene-1,4-diol + 2 chloride
1,3,4,6-tetrachloro-1,4-cyclohexadiene + H2O
2,4,5-trichloro-2,5-cyclohexadiene-1-ol + chloride
-
-
-
?
2,3,4,5,6-pentachlorocyclohexanol + H2O
2,3,5,6-tetrachlorocyclohexane-1,4-diol + chloride
beta-hexachlorocyclohexane + H2O
pentachlorocyclohexanol + chloride
-
-
-
?
delta-hexachlorocyclohexane + H2O
pentachlorocyclohexanol + chloride
-
-
-
?
1,2-dichloroethane + H2O
2-chloroethanol + chloride
-
-
-
?
1,2-dichloroethane + H2O
2-chloroethanol + chloride
-
-
-
-
?
1,2-dichloroethane + H2O
2-chloroethanol + chloride
-
-
-
?
1,2-dichloroethane + H2O
2-chloroethanol + chloride
-
-
-
-
?
1,3,4,6-tetrachloro-1,4,cyclohexadiene + 2 H2O
2,5-dichloro-2,5-cyclohexadiene-1,4-diol + 2 chloride
-
-
-
-
?
1,3,4,6-tetrachloro-1,4,cyclohexadiene + 2 H2O
2,5-dichloro-2,5-cyclohexadiene-1,4-diol + 2 chloride
-
-
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
subfamily HLD-II, substrates larger, beta-substituted
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
subfamily HLD-II, substrates larger, beta-substituted
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
subfamily HLD-II, substrates larger, beta-substituted
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
-
subfamily HLD-I, substrates small, terminally halogenated
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
-
subfamily HLD-I, substrates small, terminally halogenated
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
-
subfamily HLD-II, substrates larger, beta-substituted
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
-
subfamily HLD-III, unknown substrates
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
-
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
-
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
-
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
-
subfamily HLD-II, substrates larger, beta-substituted
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
subfamily HLD-II, substrates larger, beta-substituted
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
subfamily HLD-III, unknown substrates
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
subfamily HLD-II, substrates larger, beta-substituted
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
P51698
-
-
-
?
1-haloalkane + H2O
a primary alcohol + halide
subfamily HLD-I, substrates small, terminally halogenated
-
-
?
2,3,4,5,6-pentachlorocyclohexanol + H2O
2,3,5,6-tetrachlorocyclohexane-1,4-diol + chloride
-
-
-
?
2,3,4,5,6-pentachlorocyclohexanol + H2O
2,3,5,6-tetrachlorocyclohexane-1,4-diol + chloride
-
-
-
?
beta-hexachlorocyclohexane + H2O
2,3,4,5,6-pentachlorocyclohexanol + chloride
-
-
-
?
beta-hexachlorocyclohexane + H2O
2,3,4,5,6-pentachlorocyclohexanol + chloride
-
-
-
?
beta-hexachlorocyclohexane + H2O
2,3,4,5,6-pentachlorocyclohexanol + chloride
two-step conversion of beta-HCH to TCDL
-
-
?
beta-hexachlorocyclohexane + H2O
2,3,4,5,6-pentachlorocyclohexanol + chloride
two-step conversion of beta-HCH to TCDL
-
-
?
n-haloalkanes + H2O
primary alcohols + halide
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broad substrate range
-
-
?
n-haloalkanes + H2O
primary alcohols + halide
-
broad substrate range
-
-
?
n-haloalkanes + H2O
primary alcohols + halide
-
broad substrate range
-
-
?
n-haloalkanes + H2O
primary alcohols + halide
broad substrate range
-
-
?
n-haloalkanes + H2O
primary alcohols + halide
-
broad substrate range
-
-
?
n-haloalkanes + H2O
primary alcohols + halide
broad substrate range
-
-
?
additional information
?
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enzyme DatA hydrolyzes brominated and iodinated compounds, leading to the generation of the corresponding alcohol, a halide ion, and a proton
-
-
?
additional information
?
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Agrobacterium tumefaciens C58 / ATCC 33970
enzyme DatA hydrolyzes brominated and iodinated compounds, leading to the generation of the corresponding alcohol, a halide ion, and a proton
-
-
?
additional information
?
-
enzyme DadB possesses broad substrate range and has the highest overall activity among the identified haloalkanes dehalogenases. The enzyme prefers brominated substrates, chlorinated alkenes, and the C2-C3 substrates, including the persistent pollutants of 1,2-dichloroethane, 1,2-dichloropropane and 1,2,3-trichloropropane, but displays no detectable activity toward long-chain haloalkanes such as 1-chlorohexadecane and 1-chlorooctadecane
-
-
?
additional information
?
-
-
enzyme DadB possesses broad substrate range and has the highest overall activity among the identified haloalkanes dehalogenases. The enzyme prefers brominated substrates, chlorinated alkenes, and the C2-C3 substrates, including the persistent pollutants of 1,2-dichloroethane, 1,2-dichloropropane and 1,2,3-trichloropropane, but displays no detectable activity toward long-chain haloalkanes such as 1-chlorohexadecane and 1-chlorooctadecane
-
-
?
additional information
?
-
enzyme DadB possesses broad substrate range and has the highest overall activity among the identified haloalkanes dehalogenases. The enzyme prefers brominated substrates, chlorinated alkenes, and the C2-C3 substrates, including the persistent pollutants of 1,2-dichloroethane, 1,2-dichloropropane and 1,2,3-trichloropropane, but displays no detectable activity toward long-chain haloalkanes such as 1-chlorohexadecane and 1-chlorooctadecane
-
-
?
additional information
?
-
-
DbeA is less active and has a higher specificity towards brominated and iodinated compounds compared with DbjA
-
-
?
additional information
?
-
-
DbeA is less active and has a higher specificity towards brominated and iodinated compounds compared with DbjA
-
-
?
additional information
?
-
-
the enzyme shows a preference for terminally brominated hydrocarbons and enantioselectivity towards beta-brominated alkanes
-
-
?
