3.8.1.2: (S)-2-haloacid dehalogenase

This is an abbreviated version!
For detailed information about (S)-2-haloacid dehalogenase, go to the full flat file.

Reaction

Synonyms

2-HAD, 2-halo acid dehalogenase, 2-haloacid dehalogenase, 2-haloacid dehalogenase[ambiguous], 2-haloacid halidohydrolase[ambiguous], 2-haloalkanoate dehalogenase, 2-haloalkanoic acid dehalogenase, 2-haloalkanoid acid halidohydrolase, 2-halocarboxylic acid dehalogenase II, DEH99, dehalogenase IVa, DehL, DL-2-haloacid dehalogenase [ambiguous], HADIIBSW, HadL AJ1, L-2-DhlB, L-2-haloacid dehalogenase, L-2-MCPA dehalogenase, L-2_HAD, L-DEX, L-DEX YL, L-DEXs, L-HAD, L-HADST, L-haloacid dehalogenase, PH1421, Rhodobacteraceae family L-haloacid dehalogenase, S-2-haloacid dehalogenase, STK_25700

ECTree

     3 Hydrolases

         3.8 Acting on halide bonds

             3.8.1 In carbon-halide compounds

                3.8.1.2 (S)-2-haloacid dehalogenase

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Results	in table
10858	AA Sequence
23	Application
1	CAS Registry Number
21	Cloned(Commentary)
13	Crystallization (Commentary)
8	General Information
1	General Stability
29	Inhibitors
27	KM Value [mM]
3	Localization
7	Metals/Ions
46	Molecular Weight [Da]
90	Natural Substrates/ Products (Substrates)
28	Organic Solvent Stability
261	Organism
7	Pathway
55	PDB ID
20	pH Optimum
6	pH Range
6	pH Stability
6	pI Value
39	Protein Variants
23	Purification (Commentary)
17	Reaction
3	Reaction Type
99	Reference
4	Source Tissue
26	Specific Activity [micromol/min/mg]
4	Storage Stability
325	Substrates and Products (Substrate)
30	Subunits
68	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
9	Temperature Range [°C]
16	Temperature Stability [°C]
4	Turnover Number [1/s]

pH Range

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pH Range on EC 3.8.1.2 - (S)-2-haloacid dehalogenase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5 - 11

Ancylobacter aquaticus

-

pH 5.0: about 55% of maximal activity, pH 11.0: about 50% of maximal activity

756964

7 - 9

Pseudomonas putida

-

the enzyme reaction is retarded below pH 6.0 and the reaction is spontaneously over pH 9.0

648314

8 - 10

Azotobacter sp.

-

-

648300

8 - 10.5

Sulfurisphaera tokodaii

-

pH 8.0: about 50% of maximal activity, pH 10.5: about 80% of maximal activity

723926

9 - 11

Pseudomonas putida

Q52087

pH 9.0: about 60% of maximal activity, pH 11.0: about 60% of maximal activity

757261

9 - 11.5

Sulfurisphaera tokodaii

Q96XE7

pH 9.0: about 45% of maximal activity, pH 11.5: about 70% of maximal activity

723963