3.7.1.9: 2-hydroxymuconate-6-semialdehyde hydrolase
This is an abbreviated version!
For detailed information about 2-hydroxymuconate-6-semialdehyde hydrolase, go to the full flat file.
Word Map on EC 3.7.1.9
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3.7.1.9
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catechols
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extradiol
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sphingomonas
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2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
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2-hydroxy-6-oxohepta-2,4-dienoate
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lignin-related
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4-hydroxy-2-oxovalerate
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xylf
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paucimobilis
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5-carboxyvanillate
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4-oxalocrotonate
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m-cresol
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isopropylbenzene
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toluate
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3-methylcatechol
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molecular biology
- 3.7.1.9
- catechols
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extradiol
- sphingomonas
- 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
- 2-hydroxy-6-oxohepta-2,4-dienoate
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lignin-related
- 4-hydroxy-2-oxovalerate
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xylf
- paucimobilis
- 5-carboxyvanillate
- 4-oxalocrotonate
- m-cresol
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isopropylbenzene
- toluate
- 3-methylcatechol
- molecular biology
Reaction
Synonyms
1H-3-Hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate, 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase, 2-hydroxymuconate semialdehyde hydrolase, 2-hydroxymuconate-semialdehyde hydrolase, 2-hydroxymuconic semialdehyde hydrolase, 6-isopropyl-HODA hydrolase, CumD, HcdC, HMSH, HOD, HOD hydrolase, hydrolase, 2-hydroxymuconate semialdehyde, hydroxymuconic semialdehyde hydrolase, meta-cleavage compound hydrolase, meta-cleavage product hydrolase, MfhA, TodF, XylF
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Natural Substrates Products
Natural Substrates Products on EC 3.7.1.9 - 2-hydroxymuconate-6-semialdehyde hydrolase
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REACTION DIAGRAM
2-hydroxymuconate-6-semialdehyde + H2O
formate + 2-oxopent-4-enoate
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2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O
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formate + 2-oxopent-4-enoate
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2-hydroxy-6-oxohepta-2,4-dienoate + H2O
formate + 2-oxopent-4-enoate
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formate + 2-oxopent-4-enoate
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metabolism of 2-hydroxymuconate 6-semialdehyde through HMS hydrolase is predominant compared to metabolism by HMS dehydrogenase
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2-hydroxymuconate 6-semialdehyde + H2O
formate + 2-oxopent-4-enoate
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metabolism of 2-hydroxymuconate 6-semialdehyde through HMS hydrolase is predominant compared to metabolism by HMS dehydrogenase
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the non-inducible levels of the enzyme activity appears negligible for metabolic purposes
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additional information
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the non-inducible levels of the enzyme activity appears negligible for metabolic purposes
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additional information
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enzyme of salicylate oxidation pathway
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additional information
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enzyme is part of the pathway for the catabolism of toluene and m-xylene and p-xylene
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additional information
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enzyme of meta-cleavage pathway for the metabolism of benzoic acids to Krebs-cycle intermediates
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additional information
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enzyme of the hydrolytic branch of the meta-cleavage pathway for the catabolism of catechol and alkyl-substituted catechols
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additional information
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Pseudomonas putida mt-2 / ATCC 33015 / DSM 3931 / NCIB 12182 / NCIMB 12182
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enzyme is part of the pathway for the catabolism of toluene and m-xylene and p-xylene
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