3.7.1.8: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

This is an abbreviated version!
For detailed information about 2,6-dioxo-6-phenylhexa-3-enoate hydrolase, go to the full flat file.

Word Map on EC 3.7.1.8

3.7.1.8

biphenyls

hydrolases

dioxygenase

hopdas

benzoate

1,2-dioxygenase

2-hydroxypenta-2,4-dienoate

molecular biology

cumene

oxyanion

2,3-dihydroxybiphenyl

polychlorinated

rhodococcus

sphingomonas

ring-hydroxylating

2-hydroxy-6-oxohepta-2,4-dienoate

2-hydroxymuconic

4-chlorobiphenyl

wittichii

xenovorans

extradiol

ser-his-asp

isopropylbenzene

dibenzofuran

acyl-enzyme

carbanion

degradation

environmental protection

Reaction

Synonyms

2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoic acid hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2, 4-dienoate hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dieonic acid hydrolase, 6-phenyl HODA hydrolase, BphD, BphD enzyme, BphDP6, CarC, HOHPDA hydrolase, HOPD hydrolase, HOPDA hydrolase, HPDA hydrolase, HsaD, hydrolase, 2,6-dioxo-6-phenylhexa-3-enoate, LigY, MCP hydrolase, meta-cleavage product hydrolase, MhpC

ECTree

3 Hydrolases

3.7 Acting on carbon-carbon bonds

3.7.1 In ketonic substances

3.7.1.8 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

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Results	in table
648	AA Sequence
9	Application
1	CAS Registry Number
16	Cloned(Commentary)
1	Cofactor
8	Crystallization (Commentary)
21	General Information
19	Inhibitors
25	kcat/KM [mM/s]
3	Ki Value [mM]
70	KM Value [mM]
1	Metals/Ions
11	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
83	Organism
7	Pathway
40	PDB ID
6	pH Optimum
3	pH Range
2	pH Stability
53	Protein Variants
15	Purification (Commentary)
8	Reaction
1	Reaction Type
44	Reference
6	Specific Activity [micromol/min/mg]
4	Storage Stability
100	Substrates and Products (Substrate)
14	Subunits
76	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
2	Temperature Range [°C]
4	Temperature Stability [°C]
67	Turnover Number [1/s]

KM Value

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KM Value on EC 3.7.1.8 - 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

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0.00013 - 0.00065

(2E,4E)-2-hydroxy-6-(4-chlorophenyl)-6-oxohexa-2,4-dienoic acid

2 entries

0.00019 - 0.00047

(2E,4E)-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid

2 entries

0.00033 - 0.0129

(2E,4E)-6-(2-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid

2 entries

0.00075

(2E,4E)-6-(3,4-dichlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid

Rhodococcus globerulus

674232

0.00104

(2E,4E)-6-(3,5-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid

Rhodococcus globerulus

674232

0.00043 - 0.00046

(2E,4E)-6-(3-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid

2 entries

0.00095 - 0.0044

(2E,4Z)-2,4-dihydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid

2 entries

0.0036 - 0.004

(2E,4Z)-4-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid

2 entries

0.0049 - 0.018

(2E,4Z)-5-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid

2 entries

0.00054 - 0.0069

(2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid

2 entries

0.00028 - 0.0051

2,6-dioxo-6-phenylhexa-3-enoate

20 entries

0.0046

2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoic acid

Pseudomonas sp.

at 25°C

676944

0.14

2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate

Arthrobacter sp. YC-RL1

A0A0H0ZQK0

pH 7.0, 30°C

755881

0.00071 - 0.00085

2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate

2 entries

0.0002 - 0.008

2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid

6 entries

0.0033

4,11-dicarboxy-8-hydroxy-9-methoxy-2-hydroxy-6-oxo-6-phenyl-hexa-2,4-dienoate

Sphingobium sp. SYK-6

G2IN02

pH 7, 25°C

755670

0.31

8-(2-chlorophenyl)-2-hydroxy-5-methyl-6-oxoocta-2,4-dienoic acid

Mycobacterium tuberculosis

P9WNH5

pH 7.5, 25°C

717815

0.0017 - 0.0373

ethyl-2-acetoxy-6-keto-6-phenylhexa-2,4-dienoate

5 entries

0.002 - 0.077

meta-ring fission intermediate

11 entries

additional information

4 entries