3.7.1.4: phloretin hydrolase

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For detailed information about phloretin hydrolase, go to the full flat file.

Word Map on EC 3.7.1.4

3.7.1.4

eubacterium

ramulus

brush

flavonoid

border

medicine

2,4-diacetylphloroglucinol

lactase-phlorizin

molecular biology

lactase

pyridoxine

phloridzin

flavone

beta-glucosidic

carbon-carbon

beta-glucosidase

fluorescens

deglycosylated

mucosal

5'-phosphate

fecal

dihydrochalcone

pyridoxal

abscessus

neohesperidin

Reaction

Synonyms

C-acylphenol acylhydrolase, lactase phlorizin hydrolase, lactase phlorizin-hydrolase, lactase-phlorizin hydrolase, lactase/phlorizin hydrolase, LCT, LPH, Phlg, phloretin hydrolase, Phy, PNG hydrolase

ECTree

3 Hydrolases

3.7 Acting on carbon-carbon bonds

3.7.1 In ketonic substances

3.7.1.4 phloretin hydrolase

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Results	in table
11	Activating Compound
22	AA Sequence
7	Application
1	CAS Registry Number
10	Cloned(Commentary)
2	Crystallization (Commentary)
10	General Information
34	Inhibitors
5	kcat/KM [mM/s]
4	Ki Value [mM]
17	KM Value [mM]
14	Localization
5	Metals/Ions
8	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
31	Organism
6	pH Optimum
1	pH Range
3	Posttranslational Modification
29	Protein Variants
11	Purification (Commentary)
5	Reaction
9	Reaction Type
28	Reference
17	Source Tissue
8	Specific Activity [micromol/min/mg]
80	Substrates and Products (Substrate)
9	Subunits
50	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Stability [°C]
10	Turnover Number [1/s]

Localization

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Localization on EC 3.7.1.4 - phloretin hydrolase

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apical plasma membrane

Canis lupus familiaris

LPH traverses endosomal compartments before entering the apical membrane (fluorescence microscopic and biochemical approach)

brush border membrane

2 entries

cytosol

2 entries

endoplasmic reticulum

Homo sapiens

the recombinant precusor in COS-1 cells resides in the ER, not mature wild-type

5783

656110

endosome

Canis lupus familiaris

LPH traverses endosomal compartments before entering the apical membrane (fluorescence microscopic and biochemical approach)