3.7.1.23: maleylpyruvate hydrolase

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For detailed information about maleylpyruvate hydrolase, go to the full flat file.

Reaction

Synonyms

hbzF, maleylpyruvate hydrolase, maleylpyruvate hydrolase I, maleylpyruvate hydrolase II, Mph, MPH11, SLG_11280

ECTree

     3 Hydrolases

         3.7 Acting on carbon-carbon bonds

             3.7.1 In ketonic substances

                3.7.1.23 maleylpyruvate hydrolase

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Results	in table
2	AA Sequence
1	Cloned(Commentary)
1	Crystallization (Commentary)
2	Expression
4	General Information
4	Inhibitors
3	KM Value [mM]
2	Metals/Ions
4	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
13	Organism
4	Pathway
2	pH Optimum
2	Purification (Commentary)
1	Reaction
9	Reference
2	Specific Activity [micromol/min/mg]
4	Storage Stability
22	Substrates and Products (Substrate)
5	Subunits
16	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 3.7.1.23 - maleylpyruvate hydrolase

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SYSTEMATIC NAME

IUBMB Comments

(2Z)-4,6-dioxohept-2-enedioate acylhydrolase

The enzyme, characterized from the bacterium Pseudomonas alcaligenes NCIMB 9867, catalyses the hydrolysis of 3-maleylpyruvate, the ring-cleavage product of gentisate. The enzyme can also act on a number of maleylpyruvate derivatives, such as (2E)-2-methyl-4,6-dioxohept-2-enedioate and (2E)-3-methyl-4,6-dioxohept-2-enedioate. Activated by Mn2+. May be identical to EC 3.7.1.5, acylpyruvate hydrolase.