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3.7.1.14: 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase

This is an abbreviated version!
For detailed information about 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase, go to the full flat file.

Reaction

(2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate
+
H2O
=
(2Z)-2-hydroxypenta-2,4-dienoate
+
succinate

Synonyms

2-hydroxy-6-keto-nona-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-ketonona-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase, MCP hydrolase, meta-cleavage product hydrolase, MhpC

ECTree

     3 Hydrolases
         3.7 Acting on carbon-carbon bonds
             3.7.1 In ketonic substances
                3.7.1.14 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase

Systematic Name

Systematic Name on EC 3.7.1.14 - 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase

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SYSTEMATIC NAME
IUBMB Comments
(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase
This enzyme catalyses a step in a pathway of phenylpropanoid compounds degradation. The first step of the enzyme mechanism involves a reversible keto-enol tautomerization [4].