3.6.5.6: tubulin GTPase
This is an abbreviated version!
For detailed information about tubulin GTPase, go to the full flat file.
Word Map on EC 3.6.5.6
-
3.6.5.6
-
polymerization
-
actin
-
cytoskeleton
-
mitotic
-
spindle
-
microtubule-associated
-
taxol
-
centrosome
-
paclitaxel
-
nucleation
-
tau
-
disassembly
-
antiproliferative
-
heterodimers
-
antimitotic
-
nerve
-
vinblastine
-
interphase
-
isotypes
-
nocodazole
-
microtubular
-
neurite
-
gtpases
-
pole
-
axonemal
-
vimentin
-
polymerized
-
neurofilament
-
kinesins
-
cortical
-
gdp
-
cytokine
-
cilia
-
myosin
-
dynein
-
lattice
-
metaphase
-
map2
-
microfilaments
-
taxanes
-
anaphase
-
urchin
-
multipolar
-
catastrophe
-
vincristine
-
kinetochore
-
microtubule-based
-
nestin
-
flagella
-
docetaxel
- 3.6.5.6
- polymerization
- actin
- cytoskeleton
-
mitotic
- spindle
-
microtubule-associated
- taxol
- centrosome
- paclitaxel
-
nucleation
- tau
-
disassembly
-
antiproliferative
- heterodimers
-
antimitotic
- nerve
- vinblastine
-
interphase
-
isotypes
- nocodazole
- microtubular
-
neurite
- gtpases
- pole
-
axonemal
- vimentin
-
polymerized
- neurofilament
- kinesins
- cortical
- gdp
- cytokine
- cilia
- myosin
- dynein
-
lattice
-
metaphase
- map2
-
microfilaments
-
taxanes
-
anaphase
- urchin
-
multipolar
-
catastrophe
- vincristine
- kinetochore
-
microtubule-based
- nestin
- flagella
- docetaxel
Reaction
Synonyms
atypical GTPase, BtubB, cell division protein, EC 3.6.1.51, eFtsZ, FtsZ, FtsZ tubulin-like protein, FtsZDr, gamma-tubulin, GTP phosphohydrolase, GTPase, guanine triphosphatase, guanosine 5'-triphosphatase, guanosine triphosphatase, mFtsZ, ORF156, ribosomal GTPase, TUBG1, tubulin, tubulin FtsZ, tubulin GTPase, tubulin homolog FtsZ, tubulin-colchicine GTPase
ECTree
Advanced search results
Natural Substrates Products
Natural Substrates Products on EC 3.6.5.6 - tubulin GTPase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
GTP + H2O
GDP + phosphate
-
-
-
-
?
GTP + H2O
GDP + phosphate
-
GTP-binding proteins from the tubulin family, including alpha,beta-tubulin are key components of the cytoskeleton and play central roles in chromosome segregation and cell division. The nucleotide switch of alpha,beta-tubulin is triggered by GTP hydrolysis and regulates microtubule assembly dynamics. Unassembled tubulin-GTP is in the inactive, curved conformation as in tubulin-GDP rings, and is driven into the straight microtubule conformation by the assembly contacts. Binding of the GTP gamma-phosphate only lowers the free energy difference between the curved and straight forms
-
-
?
GTP + H2O
GDP + phosphate
-
GTP-binding proteins from the tubulin family, including alpha,beta-tubulin are key components of the cytoskeleton and play central roles in chromosome segregation and cell division. The nucleotide switch of alpha,beta-tubulin is triggered by GTP hydrolysis and regulates microtubule assembly dynamics. Unassembled tubulin-GTP is in the inactive, curved conformation as in tubulin-GDP rings, and is driven into the straight microtubule conformation by the assembly contacts. Binding of the GTP gamma-phosphate only lowers the free energy difference between the curved and straight forms
-
-
?
?
-
enzyme FtsZDr acts as a GTPase exhibiting polymerization/depolymerization dynamics in vitro and FtsZ ring formation in vivo
-
-
?
additional information
?
-
-
enzyme FtsZDr acts as a GTPase exhibiting polymerization/depolymerization dynamics in vitro and FtsZ ring formation in vivo
-
-
?