3.6.5.5: dynamin GTPase

This is an abbreviated version!
For detailed information about dynamin GTPase, go to the full flat file.

Reaction

Synonyms

AtDRP1A, B-dynamin , caSey1p, D100 , dDyn, DLC1, DLP-1, DLP1, DlpA, DlpB, DlpC, Dnm1, DNM1L, DNM2, DNM3, DRP, Drp1, Drp1-long, Drp1-short, DRP1E, DRP5A, Drp6, DrpB, Dyn, Dyn I, Dyn-1, Dyn1, DYN2, Dyn2aa, Dyn2ab, Dyn2ba, Dyn2bb, Dyn3, dynamin, dynamin 1, dynamin 1 GTPase, dynamin 1aa, dynamin 2, dynamin 2aa, dynamin 3, dynamin 3aa, Dynamin BREDNM19 , dynamin family GTPase, dynamin GTPase, dynamin I, dynamin I GTPase, dynamin I guanosine triphosphatase, Dynamin UDNM , Dynamin, brain , Dynamin, testicular , dynamin-1, dynamin-1 GTPase, dynamin-1-like GTPase, dynamin-1-like protein, dynamin-2, dynamin-3, dynamin-like GTPase, dynamin-like guanosine triphosphatase, dynamin-like guanosine-triphosphate hydrolase, dynamin-like myxovirus resistance protein A, dynamin-like protein 1, dynamin-like protein 6, dynamin-related GTPase, dynamin-related protein, dynamin-related protein 1, dynamin-related protein 1 isoform 3, dynamin-related protein 1A, dynamin-related protein 1E, dynamin-related protein 2A, dynamin-related protein B, dynamin-retated GTPase Drp1, dynamin1, dynamin2, dynamin2 GTPase, dynamine-related GTPase, dynein light chain 1, dynI, dynI GTPase, EC 3.6.1.50, fission dynamin, GTP phosphohydrolase, GTPase, GTPase dynamin, GTPase dynamin-1, GTPase dynamin-related protein 1, guanine triphosphatase, guanosine 5'-triphosphatase, guanosine triphosphatase, hDrp1 isoform 3, large GTPase, Mfn1, mitochondrial division dynamin, mitochondrial dynamin, mitochondrial inner membrane fusion dynamin Mgm1, mitofusin 1, mOPA1, multidomain GTPase, Mx GTPase, MX1, MxA, myxovirus resistance GTPase, neurolastin, Nicotiana tabacum dynamin-related protein 3, NtDRP3, OPA1, optic atrophy 1, PfDYN2, phosphatase, guanosine tri-, Protein shibire, ribosomal GTPase, Sey1p, Shibire protein , T-dynamin , Vps1p

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.5 Acting on GTP to facilitate cellular and subcellular movement

                3.6.5.5 dynamin GTPase

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Results	in table
61	Activating Compound
13562	AA Sequence
6	Application
1	CAS Registry Number
54	Cloned(Commentary)
6	Crystallization (Commentary)
2621	Disease/ Diagnostics
91	General Information
124	IC50 Value
252	Inhibitors
43	KM Value [mM]
120	Localization
22	Metals/Ions
16	Molecular Weight [Da]
115	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
147	Organism
114	PDB ID
18	pH Optimum
1	pI Value
4	Posttranslational Modification
117	Protein Variants
39	Purification (Commentary)
3	Reaction
18	Reaction Type
138	Reference
2	Renatured (Commentary)
105	Source Tissue
2	Specific Activity [micromol/min/mg]
186	Substrates and Products (Substrate)
42	Subunits
278	Synonyms
1	Systematic Name
20	Temperature Optimum [°C]
1	Temperature Range [°C]
26	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.6.5.5 - dynamin GTPase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.1

(1R,2R)-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropane-1-carboxamide

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.044

(2E)-2-cyano-N-(3-[[(2E)-2-cyano-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]propyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide

Ovis aries

-

in 10 mM Tris, 10 mM NaCl, 2 mM Mg2, at 30°C

697337

0.051

(2E)-2-cyano-N-(3-[[(2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoyl]amino]propyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide

Ovis aries

-

in 10 mM Tris, 10 mM NaCl, 2 mM Mg2, at 30°C

697337

0.146

(2E)-2-cyano-N-(3-[[(2E)-2-cyano-3-phenylprop-2-enoyl]amino]propyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide

Ovis aries

-

in 10 mM Tris, 10 mM NaCl, 2 mM Mg2, at 30°C

697337

0.0051

(2E,2'E)-N,N'-(2-hydroxypropane-1,3-diyl)bis[2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide]

Ovis aries

-

in 10 mM Tris, 10 mM NaCl, 2 mM Mg2, at 30°C

697337

0.5

(2E,2'E)-N,N'-(2-phenoxypropane-1,3-diyl)bis[2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide]

Ovis aries

-

IC50 above 0.5 mM, in 10 mM Tris, 10 mM NaCl, 2 mM Mg2, at 30°C

697337

0.5

(2E,2'E)-N,N'-(2-propoxypropane-1,3-diyl)bis[2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide]

Ovis aries

-

IC50 above 0.5 mM, in 10 mM Tris, 10 mM NaCl, 2 mM Mg2, at 30°C

697337

0.0234

(3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-piperidine

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.05

(5Z)-3-benzyl-5-(3,5-dichlorobenzylidene)-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.134

(5Z)-3-benzyl-5-(4-bromobenzylidene)-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0074

(5Z)-3-benzyl-5-[(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.022

(5Z)-3-benzyl-5-[4-[3-(dimethylamino)propoxy]benzylidene]-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0074

(5Z)-5-(2,1,3-benzoxadiazol-5-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.053

(5Z)-5-(2,1,3-benzoxadiazol-5-ylmethylidene)-3-benzyl-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.09

(5Z)-5-(2H-chromen-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0075

(5Z)-5-(3,5-dichlorobenzylidene)-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.031

(5Z)-5-(3,5-dichlorobenzylidene)-3-(prop-2-en-1-yl)-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0031

(5Z)-5-(3,5-dichlorobenzylidene)-3-ethyl-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.043

(5Z)-5-(quinoxalin-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0055

(5Z)-5-[(5-chloro-1-benzothiophen-3-yl)methylidene]-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.029

(5Z)-5-[(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0051

(5Z)-5-[(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-3-ethyl-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0045

(5Z)-5-[4-[3-(dimethylamino)propoxy]benzylidene]-3-(prop-2-en-1-yl)-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0071

(5Z)-5-[4-[3-(dimethylamino)propoxy]benzylidene]-3-ethyl-2-thioxo-1,3-thiazolidin-4-one

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.1

1,2,3,4,10,14b-hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.1

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro[2]benzofuran-5-carbonitrile

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.1

10,11-dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepine

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.3

2,5-bis(2-(dimethylamino)ethylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.3

2,5-bis(2-(hydroxymethyl)anilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.387

2,5-bis(2-bromoanilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0502

2,5-bis(2-carboxyanilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.58

2,5-bis(3-bromopropylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0254

2,5-bis(3-carboxyanilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0579

2,5-bis(3-hydroxyanilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.3

2,5-bis(3-methoxyanilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.116

2,5-bis(3-methoxypropylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0215

2,5-bis(4-(hydroxymethyl)phenylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0106

2,5-bis(4-carboxyanilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.029

2,5-bis(4-carboxybenzylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0111

2,5-bis(4-hydroxyanilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.112

2,5-bis(4-hydroxybenzylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.3

2,5-bis(4-methoxyanilino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.17

2,5-bis(4-methoxybenzylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.3

2,5-bis(hexylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.273

2,5-bis-(benzylamino)-1,4-benzoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.314

2-(2-carboxyanilino)-1,4-naphthoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0303

2-(3-(hydroxymethyl)anilino)-1,4-naphthoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.109

2-(3-hydroxyanilino)-1,4-naphthoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0295

2-(4-(hydroxymethyl)anilino)-1,4-naphthoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.0224

2-(4-hydroxyanilino)-1,4-naphthoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.15

2-(4-hydroxybenzylamino)-1,4-naphthoquinone

Ovis aries

-

pH and temperature not specified in the publication

733785

0.264

2-chloro-4-(2-dimethylaminopropylamine)-6-methylpyrimidine

Homo sapiens

Q05193

pH and temperature not specified in the publication

757390

0.061

2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid 2-[2-cyano-3-(3,4-dihydroxyphenyl)acryloyloxy]butyl ester

Ovis aries

-

IC50: 0.061 mM

669796

0.042

2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid 2-[2-cyano-3-(3,4-dihydroxyphenyl)acryloyloxy]ethyl ester

Ovis aries

-

IC50: 0.042 mM

669796

0.038

2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid 2-[2-cyano-3-(3,4-dihydroxyphenyl)acryloyloxy]propyl ester

Ovis aries

-

IC50: 0.038 mM

669796

0.0017

2-cyano-N-[2-[2-cyano-3-(3,4,5-trihydroxyphenyl)acryloylamino]ethyl]-3-(3,4,5-trihydroxyphenyl)acrylamide

Ovis aries

-

IC50: 0.0017 mM

669796

0.009

2-cyano-N-[2-[2-cyano-3-(3,4-dihydroxy-4-methoxyphenyl)acryloylamino]ethyl]-3-(3,4-dihydroxy-5-methoxyphenyl) acrylamide

Ovis aries

-

IC50: 0.009 mM

669796

0.006

2-cyano-N-[3-[2-cyano-3-(3,4,5-trihydroxyphenyl)acryloylamino]hexyl]-3-(3,4,5-trihydroxyphenyl)acrylamide

Ovis aries

-

IC50: 0.006 mM

669796

0.08

2-cyano-N-[3-[2-cyano-3-(3,4-dihydroxy-5-methoxy-phenyl)acryloylamino]hexyl]-3-(3,4-dihydroxy-5-methoxyphenyl)acrylamide

Ovis aries

-

IC50: 0.08 mM

669796

0.008

2-cyano-N-[3-[2-cyano-3-(3,4-dihydroxy-5-methoxy-phenyl)acryloylamino]pentyl]-3-(3,4-dihydroxy-5-methoxyphenyl)acrylamide

Ovis aries

-

IC50: 0.008 mM

669796

0.008

2-cyano-N-[3-[2-cyano-3-(3,4-dihydroxy-5-methoxyphenyl)acryloylamino]butyl]-3-(3,4-dihydroxy-5-methoxyphenyl)acrylamide

Ovis aries

-

IC50: 0.008 mM

669796

0.005

2-cyano-N-[3-[2-cyano-3-(3,4-dihydroxy-5-methoxyphenyl)acryloylamino]propyl]-3-(3,4-dihydroxy-5-meth-oxyphenyl)acrylamide

Ovis aries

-

IC50: 0.005 mM

669796

0.0051

2-cyano-N-[3-[2-cyano-3-(3,4-dihydroxyphenyl)acryloylamino]-2-hydroxypropyl]-3-(3,4-dihydroxyphenyl)acrylamide

Ovis aries

-

IC50: 0.0051 mM

669796

0.0369

2-cyano-N-[3-[2-cyano-3-(3,4-dihydroxyphenyl)acryloylamino]-propyl] 3-[4-(3-trifluoromethyl-3H-diazirin-3-yl)phenyl]acrylamide

Ovis aries

-

in 10 mM Tris, 10 mM NaCl, 2 mM Mg2+, at 30°C

697337

0.0372

2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.064

3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.0472

3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-propan-1-amine

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.0064

3-(4-azidophenyl)-2-cyano-N-[3-[2-cyano-3-(3,4-dihydroxyphenyl)acryloylamino]propyl]acrylamide

Ovis aries

-

in 10 mM Tris, 10 mM NaCl, 2 mM Mg2+, at 30°C

697337

0.1

3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.0299

3-(9-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.3

3-sulfo-N-(2-hydroxyethyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.0235

3-[(5Z)-5-(2H-chromen-3-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0044

3-[(5Z)-5-(3,5-dichlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.096

3-[(5Z)-5-(4-bromobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.042

3-[(5Z)-5-(biphenyl-4-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.048

3-[(5Z)-5-[(5-chloro-1-benzothiophen-3-yl)methylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.01

3-[(5Z)-5-[(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.404

4-(N,N-dimethyl-N-butyl-N-ethyl)-4-aza-10-oxatricyclo[5.2.1]decane-3,5-dione methanesulfonate

Ovis aries

-

-

689237

0.0085

4-(N,N-dimethyl-N-dodecyl-N-ethyl)-4-aza-10-oxatricyclo[5.2.1]decane-3,5-dione bromide

Ovis aries

-

-

689237

0.0089

4-(N,N-dimethyl-N-dodecyl-N-ethyl)-4-aza-10-oxatricyclo[5.2.1]decane-3,5-dione methanesulfonate

Ovis aries

-

-

689237

0.0068

4-(N,N-dimethyl-N-dodecyl-N-propyl)-4-aza-10-oxa-6-ethyltricyclo[5.2.1]decane-3,5-dione methanesulfonate

Ovis aries

-

-

689237

0.0118

4-(N,N-dimethyl-N-dodecyl-N-propyl)-4-aza-10-oxa-6-methyltricyclo[5.2.1]decane-3,5-dione methanesulfonate

Ovis aries

-

-

689237

0.0084

4-(N,N-dimethyl-N-dodecyl-N-propyl)-4-aza-10-oxatricyclo[5.2.1]decane-3,5-dione bromide

Ovis aries

-

-

689237

0.0112

4-(N,N-dimethyl-N-dodecyl-N-propyl)-4-aza-10-oxatricyclo[5.2.1]decane-3,5-dione methanesulfonate

Ovis aries

-

-

689237

0.0023

4-(N,N-dimethyl-N-octadecyl-N-ethyl)-4-aza-10-oxatricyclo[5.2.1]decane-3,5-dione bromide

Ovis aries

-

-

689237

0.043

4-(N-methyl-N-ethylpiperidine)-4-aza-10-oxatricyclo[5.2.1]decane-3,5-dione methanesulfonate

Ovis aries

-

-

689237

0.509

4-amino-3-sulfo-N-(2-(dimethylamino)ethyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.155

4-amino-3-sulfo-N-(2-aminobenzyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.3

4-amino-3-sulfo-N-(2-aminoethyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.094

4-amino-3-sulfo-N-(2-carboxyethyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.193

4-amino-3-sulfo-N-(2-hydroxyethyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.088

4-amino-3-sulfo-N-(3-aminobenzyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.159

4-amino-3-sulfo-N-(3-hydroxyphenyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.093

4-amino-3-sulfo-N-(3-hydroxypropyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.123

4-amino-3-sulfo-N-(4-aminobenzyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.0185

4-amino-3-sulfo-N-(4-carboxybenzyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.0448

4-amino-3-sulfo-N-(4-hydroxybenzyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.296

4-amino-3-sulfo-N-(4-hydroxyphenyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.113

4-amino-3-sulfo-N-(5-hydroxyhexyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.062

4-amino-3-sulfo-N-(5-hydroxypentyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.0191

4-amino-3-sulfo-N-(carboxymethyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.0703

4-amino-3-sulfo-N-benzyl-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.3

4-amino-3-sulfo-N-phenyl-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.5

4-azido-N-(2-[2-cyano-3-(3,4-dihydroxyphenyl)acryloylamino]-1-[[2-cyano-3-(3,4-dihydroxyphenyl)acryloylamino]methyl]ethyl)-2,3,5,6-tetrafluorobenzamide

Ovis aries

-

IC50 above 0.5 mM, in 10 mM Tris, 10 mM NaCl, 2 mM Mg2+, at 30°C

697337

0.3

4-sulfo-N-(2-hydroxyethyl)-1,8-naphthalimide

Homo sapiens

Q05193

pH 7.4, 37°C

734826

0.1

4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.1

5H-dibenz[b,f]azepine-5-carboxamide

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.0017

bis-tyrphostin

Ovis aries

-

in 10 mM Tris, 10 mM NaCl, 2 mM Mg2+, at 30°C

697337

0.0051

catechol-acrylamide

Ovis aries

-

IC50: 0.0051 mM

669796

0.0147

fluvoxamine

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.1

methyl 2-phenyl-2-(2-piperidyl)acetate

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.0241

myristyl trimethyl ammonium bromide

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.1

N-(2-diethylaminoethyl)-2-methoxy-5-methylsulfonyl-benzamide

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.0334

N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.0211

N-methyl-9,10-ethanoanthracene-9(10H)-propanamine

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.1

N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoyl-benzamide

Mus musculus

-

IC50 above 0.1 mM, in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.5

N-[2-[[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-1-([[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]methyl)ethyl]benzamide

Ovis aries

-

IC50 above 0.5 mM, in 10 mM Tris, 10 mM NaCl, 2 mM Mg2, at 30°C

697337

0.327

N1-(4-chloro-6-methylpyrimidin-2-yl)-N3,N3-dimethylpropane-1,3-diamine

Homo sapiens

Q05193

pH and temperature not specified in the publication

757390

0.0073

sertraline

Mus musculus

-

in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30°C

696551

0.0055

[(5Z)-5-(3,5-dichlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.073

[(5Z)-5-(biphenyl-4-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0123

[(5Z)-5-[(5-chloro-1-benzothiophen-3-yl)methylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

0.0034

[(5Z)-5-[(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid

Homo sapiens

-

pH and temperature not specified in the publication

718468

additional information

additional information

Homo sapiens

Q05193

IC50 values, overview

757390

-