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3.6.4.B7: RadA recombinase

This is an abbreviated version!
For detailed information about RadA recombinase, go to the full flat file.

Word Map on EC 3.6.4.B7

Reaction

ATP
+
H2O
=
ADP
 +
phosphate

Synonyms

DNA repair and recombination protein, DNA repair protein RAD51 homolog 1, Hvo RadA, MvRadA, Pho RadA, PhoRadA, Rad51, RadA, RadA intein, RadA recombinase, RadA/Sms, RadC1, RadC2, SMS, SSO0250, SsoRadA, SsoRadA recombinase, SsRada

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
                3.6.4.B7 RadA recombinase

Reference

topprint

Reference on EC 3.6.4.B7 - RadA recombinase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Graham, W.J.; Haseltine, C.A.
A recombinase paralog from the hyperthermophilic crenarchaeon Sulfolobus solfataricus enhances SsoRadA ssDNA binding and strand displacement
Gene
515
128-139
2013
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q55075)
Manually annotated by BRENDA team
McIlwraith, M.J.; Hall, D.R.; Stasiak, A.Z.; Stasiak, A.; Wigley, D.B.; West, S.C.
RadA protein from Archaeoglobus fulgidus forms rings, nucleoprotein filaments and catalyses homologous recombination
Nucleic Acids Res.
29
4509-4517
2001
Archaeoglobus fulgidus (O29269), Archaeoglobus fulgidus
Manually annotated by BRENDA team
Li, Y.; He, Y.; Luo Y.
Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis
Acta Crystallogr. Sect. D
65
602-610
2009
Methanococcus maripaludis (P0CW58), Methanococcus maripaludis
Manually annotated by BRENDA team
Du, L.; Luo, Y.
Structure of a hexameric form of RadA recombinase from Methanococcus voltae
Acta Crystallogr. Sect. F
68
511-516
2012
Methanococcus voltae (O73948), Methanococcus voltae
Manually annotated by BRENDA team
Lee, M.H.; Leng, C.H.; Chang, Y.C.; Chou, C.C.; Chen, Y.K.; Hsu, F.F.; Chang, C.S.; Wang, A.H., Wang, T.F.
Self-polymerization of archaeal RadA protein into long and fine helical filaments
Biochem. Biophys. Res. Commun.
323
845-851
2004
Saccharolobus solfataricus
Manually annotated by BRENDA team
Qian, X.; Wu, Y.; He, Y.; Luo, Y.
Crystal structure of Methanococcus voltae RadA in complex with ADP: hydrolysis-induced conformational change
Biochemistry
44
13753-13761
2005
Methanococcus voltae (O73948), Methanococcus voltae
Manually annotated by BRENDA team
Qian, X.; He, Y.; Luo, Y.
Binding of a second magnesium is required for ATPase activity of RadA from Methanococcus voltae
Biochemistry
46
5855-5863
2007
Methanococcus voltae (O73948), Methanococcus voltae
Manually annotated by BRENDA team
Graham, W.J. 5th; Rolfsmeier, M.L.; Haseltine, C.A.
An archaeal RadA paralog influences presynaptic filament formation
DNA Repair
12
403-413
2013
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q55075)
Manually annotated by BRENDA team
Spies, M.; Kil, Y.; Masui, R.; Kato, R.; Kujo, C.; Ohshima, T.; Kuramitsu, S.; Lanzov, V.
The RadA protein from a hyperthermophilic archaeon Pyrobaculum islandicum is a DNA-dependent ATPase that exhibits two disparate catalytic modes, with a transition temperature at 75°C
Eur. J. Biochem.
267
1125-1137
2000
Pyrobaculum islandicum (Q9UWR5), Pyrobaculum islandicum, Pyrobaculum islandicum DSM 4184 (Q9UWR5)
Manually annotated by BRENDA team
Seitz, E.M.; Brockman, J.P.; Sandler, S.J.; Clark, A.J.; Kowalczykowski, S.C.
RadA protein is an archaeal RecA protein homolog that catalyzes DNA strand exchange
Genes Dev.
12
1248-1253
1998
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q55075)
Manually annotated by BRENDA team
Kil, Y.V.; Baitin, D.M.; Masui, R.; Bonch-Osmolovskaya, E.A.; Kuramitsu, S.; Lanzov, V.A.
Efficient strand transfer by the RadA recombinase from the hyperthermophilic archaeon Desulfurococcus amylolyticus
J. Bacteriol.
182
130-134
2000
Desulfurococcus amylolyticus (Q9Y8J4), Desulfurococcus amylolyticus
Manually annotated by BRENDA team
Kil, Y.V.; Glazunov, E.A.; Lanzov, V.A.
Characteristic thermodependence of the RadA recombinase from the hyperthermophilic archaeon Desulfurococcus amylolyticus
J. Bacteriol.
187
2555-2557
2005
Desulfurococcus amylolyticus (Q9Y8J4), Desulfurococcus amylolyticus
Manually annotated by BRENDA team
Komori, K.; Miyata, T.; DiRuggiero, J.; Holley-Shanks, R.; Hayashi, I.; Cann, I.K.; Mayanagi, K.; Shinagawa, H.; Ishino, Y.
Both RadA and RadB are involved in homologous recombination in Pyrococcus furiosus
J. Biol. Chem.
275
33782-33790
2000
Pyrococcus furiosus (O74036), Pyrococcus furiosus
Manually annotated by BRENDA team
Komori, K.; Miyata, T.; Daiyasu, H.; Toh, H.; Shinagawa, H.; Ishino, aY.
Domain analysis of an archaeal RadA protein for the strand exchange activity
J. Biol. Chem.
275
33791-33797
2000
Pyrococcus furiosus (O74036), Pyrococcus furiosus
Manually annotated by BRENDA team
Komori, K.; Ishino, Y.
Replication protein A in Pyrococcus furiosus is involved in homologous DNA recombination
J. Biol. Chem.
276
25654-25660
2001
Pyrococcus furiosus
Manually annotated by BRENDA team
Qian, X.; He, Y.; Wu, Y.; Luo, Y.
Asp302 determines potassium dependence of a RadA recombinase from Methanococcus voltae
J. Mol. Biol.
360
537-547
2006
Methanococcus voltae (O73948), Methanococcus voltae
Manually annotated by BRENDA team
Rolfsmeier, M.L.; Haseltine, C.A.
The single-stranded DNA binding protein of Sulfolobus solfataricus acts in the presynaptic step of homologous recombination
J. Mol. Biol.
397
31-45
2010
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus
Manually annotated by BRENDA team
Wu, Y.; He, Y.; Moya, I.A.; Qian, X.; Luo, Y.
Crystal structure of archaeal recombinase RADA: a snapshot of its extended conformation
Mol. Cell.
15
423-435
2004
Methanococcus voltae (O73948), Methanococcus voltae
Manually annotated by BRENDA team
Seitz, E.M.; Kowalczykowski, S.C.
The DNA binding and pairing preferences of the archaeal RadA protein demonstrate a universal characteristic of DNA strand exchange proteins
Mol. Microbiol.
37
555-560
2000
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q55075)
Manually annotated by BRENDA team
Ariza, A.; Richard, D.J.; White, M.F.; Bond, C.S.
Conformational flexibility revealed by the crystal structure of a crenarchaeal RadA
Nucleic Acids Res.
33
1465-1473
2005
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q55075)
Manually annotated by BRENDA team
Chen, L.T.; Ko, T.P.; Chang, Y.C.; Lin, K.A.; Chang, C.S.; Wang, A.H.; Wang, T.F.
Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins
Nucleic Acids Res.
35
1787-1801
2007
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus P2 (Q55075)
Manually annotated by BRENDA team
Haseltine, C.A.; Kowalczykowski, S.C.
An archaeal Rad54 protein remodels DNA and stimulates DNA strand exchange by RadA
Nucleic Acids Res.
37
2757-2770
2009
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus
Manually annotated by BRENDA team
Chen, L.T.; Ko, T.P.; Chang, Y.W.; Lin, K.A.; Wang, A.H.; Wang, T.F.
Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RADA protein
PLoS One
2
e858
2007
Saccharolobus solfataricus (Q55075)
Manually annotated by BRENDA team
Zhang, C.; Tian, B.; Li, S.; Ao, X.; Dalgaard, K.; Goekce, S.; Liang, Y.; She, Q.
Genetic manipulation in Sulfolobus islandicus and functional analysis of DNA repair genes
Biochem. Soc. Trans.
41
405-410
2013
Sulfolobus islandicus
Manually annotated by BRENDA team
Han, W.; Shen, Y.; She, Q.
Nanobiomotors of archaeal DNA repair machineries: current research status and application potential
Cell Biosci.
4
32
2014
Archaeoglobus fulgidus, Sulfolobus islandicus, Sulfurisphaera tokodaii, Methanococcus voltae (O73948), Pyrococcus furiosus (O74036), Saccharolobus solfataricus (Q55075), Thermoplasma acidophilum (Q9HJ68), Saccharolobus solfataricus P2 (Q55075), Thermoplasma acidophilum ATCC 25905 (Q9HJ68)
Manually annotated by BRENDA team
Flores, G.E.; Wagner, I.D.; Liu, Y.; Reysenbach, A.L.
Distribution, abundance, and diversity patterns of the thermoacidophilic deep-sea hydrothermal vent euryarchaeota 2
Front. Microbiol.
3
47
2012
Aciduliprofundum boonei, Aciduliprofundum boonei T469
Manually annotated by BRENDA team
Stefanska, A.; Gaffke, L.; Kaczorowska, A.K.; Plotka, M.; Dabrowski, S.; Kaczorowski, T.
Highly thermostable RadA protein from the archaeon Pyrococcus woesei enhances specificity of simplex and multiplex PCR assays
J. Appl. Genet.
57
239-249
2016
Pyrococcus woesei (A0A0D3MA54), Pyrococcus woesei DSM 3773 (A0A0D3MA54)
Manually annotated by BRENDA team
Oeemig, J.S.; Zhou, D.; Kajander, T.; Wlodawer, A.; Iwai, H.
NMR and crystal structures of the Pyrococcus horikoshii RadA intein guide a strategy for engineering a highly efficient and promiscuous intein
J. Mol. Biol.
421
85-99
2012
Pyrococcus horikoshii (O58001), Pyrococcus horikoshii, Pyrococcus horikoshii ATCC 700860 (O58001)
Manually annotated by BRENDA team
Wang, L.; Sheng, D.; Han, W.; Huang, B.; Zhu, S.; Ni, J.; Li, J.; Shen, Y.
Sulfolobus tokodaii RadA paralog, stRadC2, is involved in DNA recombination via interaction with RadA and Hjc
Sci. China Life Sci.
55
261-267
2012
Sulfurisphaera tokodaii (Q975Y1), Sulfurisphaera tokodaii
Manually annotated by BRENDA team
Liu, J.; Ekanayake, O.; Santoleri, D.; Walker, K.; Rozovsky, S.
Efficient generation of hydrazides in proteins by RadA split intein
ChemBioChem
20
1-8
2019
Pyrococcus horikoshii (O58001), Pyrococcus horikoshii DSM 12428 (O58001), Pyrococcus horikoshii NBRC 100139 (O58001), Pyrococcus horikoshii JCM 9974 (O58001), Pyrococcus horikoshii ATCC 700860 (O58001), Pyrococcus horikoshii OT-3 (O58001)
Manually annotated by BRENDA team
Cooper, D.; Lovett, S.
Recombinational branch migration by the RadA/Sms paralog of RecA in Escherichia coli
eLife
5
e10807
2016
Escherichia coli (P24554), Escherichia coli
Manually annotated by BRENDA team
Marsh, M.E.; Scott, D.E.; Ehebauer, M.T.; Abell, C.; Blundell, T.L.; Hyvoenen, M.
ATP half-sites in RadA and RAD51 recombinases bind nucleotides
FEBS open bio
6
372-385
2016
Homo sapiens, Pyrococcus horikoshii (O58001), Pyrococcus horikoshii DSM 12428 (O58001), Pyrococcus horikoshii NBRC 100139 (O58001), Pyrococcus horikoshii JCM 9974 (O58001), Pyrococcus horikoshii ATCC 700860 (O58001), Pyrococcus horikoshii OT-3 (O58001)
Manually annotated by BRENDA team
Rolfsmeier, M.; Haseltine, C.
The RadA recombinase and paralogs of the hyperthermophilic archaeon Sulfolobus solfataricus
Methods Enzymol.
600
255-284
2018
Saccharolobus solfataricus (Q55075), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q55075), Saccharolobus solfataricus JCM 11322 (Q55075), Saccharolobus solfataricus ATCC 35092 (Q55075), Saccharolobus solfataricus DSM 1617 (Q55075)
Manually annotated by BRENDA team
Patoli, B.B.; Winter, J.A.; Patoli, A.A.; Delahay, R.M.; Bunting, K.A.
Co-expression and purification of the RadA recombinase with the RadB paralog from Haloferax volcanii yields heteromeric ring-like structures
Microbiology
163
1802-1811
2017
Haloferax volcanii (Q48328), Haloferax volcanii, Haloferax volcanii NCIMB 2012 (Q48328), Haloferax volcanii JCM 8879 (Q48328), Haloferax volcanii DS2 (Q48328), Haloferax volcanii DSM 3757 (Q48328), Haloferax volcanii ATCC 29605 (Q48328), Haloferax volcanii NBRC 14742 (Q48328), Haloferax volcanii VKM B-1768 (Q48328)
Manually annotated by BRENDA team
Mason, J.M.; Dusad, K.; Wright, W.D.; Grubb, J.; Budke, B.; Heyer, W.D.; Connell, P.P.; Weichselbaum, R.R.; Bishop, D.K.
RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells
Nucleic Acids Res.
43
3180-3196
2015
Homo sapiens (Q06609), Homo sapiens
Manually annotated by BRENDA team
Topilina, N.I.; Novikova, O.; Stanger, M.; Banavali, N.K.; Belfort, M.
Post-translational environmental switch of RadA activity by extein-intein interactions in protein splicing
Nucleic Acids Res.
43
6631-6648
2015
Pyrococcus horikoshii (O58001), Pyrococcus horikoshii, Pyrococcus horikoshii OT-3 (O58001)
Manually annotated by BRENDA team
Torres, R.; Serrano, E.; Alonso, J.
Bacillus subtilis RecA interacts with and loads RadA/Sms to unwind recombination intermediates during natural chromosomal transformation
Nucleic Acids Res.
47
9198-9215
2019
Bacillus subtilis (P37572), Bacillus subtilis, Bacillus subtilis 168 (P37572)
Manually annotated by BRENDA team