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3.6.1.B17: ATP-independent RNA helicase

This is an abbreviated version!
For detailed information about ATP-independent RNA helicase, go to the full flat file.

Word Map on EC 3.6.1.B17

Reaction

In vitro the enzyme unwinds double-strandet RNA independently of ATP =

Synonyms

2CATPase, ATP-independent RNA annealing activity, ATP-independent RNA helicase, AtRH57, DEAD-box RNA helicase, DENV helicase, DENV NS3, nonstructural protein 3, NS3, NS3 helicase, p41, protein NS3, Prp28

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.B17 ATP-independent RNA helicase

Substrates Products

Substrates Products on EC 3.6.1.B17 - ATP-independent RNA helicase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + H2O
ADP + phosphate
show the reaction diagram
CTP + H2O
CDP + phosphate
show the reaction diagram
DNA hybrid helix + H2O
?
show the reaction diagram
-
least efficient substrate
-
-
?
GTP + H2O
GDP + phosphate
show the reaction diagram
RNA helix + H2O
?
show the reaction diagram
-
-
-
-
?
RNA hybrid helix + H2O
?
show the reaction diagram
-
although the the enzyme unwinds the 3'-protruded helix in an ATP-dependent manner, it unwinds the 5'-protruded helix exactly like an RNA chaperone, which is able to unwind the helix in the absence of ATP, and increasing ATP concentrations cannot further enhance the helix unwinding
-
-
?
RNA-DNA hybrid with longer DNA strand + H2O
?
show the reaction diagram
-
-
-
-
?
RNA-DNA hybrid with longer RNA strand + H2O
?
show the reaction diagram
-
-
-
-
?
UTP + H2O
UDP + phosphate
show the reaction diagram
additional information
?
-