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3.6.1.9: nucleotide diphosphatase

This is an abbreviated version!
For detailed information about nucleotide diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.9

Reaction

a nucleoside triphosphate
+
H2O
=
A nucleotide
 +
diphosphate

Synonyms

ADPglucose pyrophosphatase/phosphodiesterase, AGPPase, AGPPase1, AGPPase2, alkaline sphingomyelinase nucleotide pyrophosphatase phosphodiesterase 7, Apyrase, ASMTL-Maf, BSU28050, CBS-PPase, CBS-pyrophosphatase, CD203c, CD39, diphosphopyridine nucleotide pyrophosphatase, dITP pyrophosphatase, dITPase, E-NPP, E-NPP1, E-NPP3, E-NTPDase, E-type ATPDase, EC 3.6.1.19, ecto-ATP-diphosphohydrolase, ecto-ATPDase, ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleoside triphosphate diphosphohydrolase 2, ecto-nucleotide phosphodiesterase/pyrophosphatase 6 eNPP6, ecto-nucleotide pyrophosphatase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-nucleotide pyrophosphatase/phosphodiesterase I-3, ecto-nucleotide pyrophosphatase/phosphodiesterase1, ecto-nucleotide pyrophosphatase/phosphodiesterase3, ecto-nucleotide pyrophosphatase/phosphodiesterases, ectonucleotide pyrophosphatase/phosphodiesterase, ectonucleotide pyrophosphatase/phosphodiesterase 1, ectonucleotide pyrophosphatase/phosphodiesterase family member 3, ENPP1, ENPP3, ENTPD1, Entpd6, family II pyrophosphatase, h-NPP-1, h-NPP-3, h-NPP1, h-NPP3, HAM1, inosine triphosphatase, inosine triphosphate pyrophosphatase, inosine triphosphate pyrophosphohydrolase, ITPA, ITPase, Maf protein, Maf-like protein YhdE, MazG, MazG protein, MazG-related protein, More, MutT, NPP, NPP 1, NPP 2, NPP 3, NPP-5, NPP1, NPP2, NPP3, NPP6, NPP7, NPPase, NPPr, NTPDase, nucleoside triphosphate diphosphatase, nucleoside triphosphate diphosphohydrolase, nucleoside triphosphate pyrophosphatase, nucleoside triphosphate pyrophosphohydrolase, nucleoside-triphosphate pyrophosphatase, nucleotide pyrophosphastases/phosphodiesterases1, nucleotide pyrophosphastases/phosphodiesterases3, nucleotide pyrophosphatase, nucleotide pyrophosphatase-1, nucleotide pyrophosphatase-3, nucleotide pyrophosphatase-5, nucleotide pyrophosphatase/phosphodiesterase, nucleotide pyrophosphatase/phosphodiesterase 1, nucleotide pyrophosphatase/phosphodiesterase NPP1, nucleotide pyrophosphatase/phosphodiesterase-1, nucleotide pyrophosphatase/phosphodiesterase-I, nucleotide pyrophosphatase/phosphodiesterases, nucleotide pyrophosphohydrolase, nucleotide-sugar pyrophosphatase, nucleotide-sugar pyrophosphatase/phosphodiesterase, ONPP, PC-1, plasma cell membrane glycoprotein-1, PPase, pyrophosphatase, nucleoside triphosphate, RdgB, RS21-C6, SAGPPase1, SAGPPase2, Tm-MazG, TM0159, TM0913, YhdE, YJR069C, YOR111W, ZmNPP1, ZmNPP2, ZmNPP3

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.9 nucleotide diphosphatase

KCat KM Value

KCat KM Value on EC 3.6.1.9 - nucleotide diphosphatase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
164.4
2',3''-cGAMP
pH and temperature not specified in the publication, soluble enzyme
13.35
4-nitrophenyl-5'-adenosine monophosphate
pH and temperature not specified in the publication, soluble enzyme
100.45
4-nitrophenyl-5'-thymidine monophosphate
pH and temperature not specified in the publication, soluble enzyme
68 - 109.7
adenosine 5'-phosphosulfate
104.5 - 297
ADP
186 - 267.5
ADP-glucose
264.3
ADP-ribose
pH 6.0, 37°C
275.6
Ap4A
pH and temperature not specified in the publication, soluble enzyme
0.198 - 674.4
ATP
2000
bis(4-nitrophenyl) phosphate
-
in 0.1 M glycine-NaOH, pH 8.9, at 37°C
27 - 171.5
bis(4-nitrophenyl)phosphate
18.95
cAMP
pH and temperature not specified in the publication, soluble enzyme
47
CDP
pH 4.5, 37°C
139
CDP-glucose
pH 6.0, 37°C
0.298 - 7.25
CTP
0.35
dATP
pH 8.0, 70°C
0.57
dCTP
pH 8.0, 70°C
0.94
dGTP
pH 8.0, 70°C
18 - 175
diphosphate
1160
dITP
pH 8.5, 37°C
0.44 - 503
dTTP
32
GDP
pH 4.5, 37°C
189
GDP-mannose
pH 6.0, 37°C
0.68 - 195.2
GTP
40
IDP
pH 4.5, 37°C
1140
ITP
pH 8.5, 37°C
11000000
S-5'-deoxyadenosylglutathione
-
in 0.1 M glycine-NaOH, pH 8.9, at 37°C
34 - 81
TDP
45 - 206
TDP-glucose
84 - 203
UDP
72 - 188
UDP-glucose
0.16 - 191
UTP
1120
xanthosine 5'-triphosphate
pH 8.5, 37°C