3.6.1.7: acylphosphatase

This is an abbreviated version!
For detailed information about acylphosphatase, go to the full flat file.

Word Map on EC 3.6.1.7

3.6.1.7

horse

native-like

ca2+-atpase

solfataricus

trifluoroethanol

phosphoenzyme

acylphosphates

thioflavine

ototoxicity

amyloid-like

protofibrils

medicine

Reaction

Synonyms

1,3-diphosphoglycerate phosphatase, acetic phosphatase, acetyl phosphatase, acetylphosphatase, ACP, AcPDRo2, acyl phosphatase, acyl phosphate phosphohydrolase, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, erythrocyte/testis isozyme, Acylphosphate phosphohydrolase, acylphosphate phosphomonohydrolase, Acyp, ACYP2, carbamoylphosphate phosphatase, carbamyl phosphate phosphatase, Ch1, Ch2, GP 1-3, GP1, GP2, GP3, Ho 1-3, Ho1, Ho2, Ho3, human common-type acylphosphatase, Isozyme CH1, Isozyme CH2, Isozyme TU1, More, muscle-type acylphosphatase 2, native acylphosphatase, PhAcP, phosphatase, acyl, Sso AcP, SSO0887, T1, TT0497

ECTree

3 Hydrolases

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.1.7 acylphosphatase

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Results	in table
4	Activating Compound
29259	AA Sequence
1	Application
1	CAS Registry Number
29	Cloned(Commentary)
26	Crystallization (Commentary)
178	Disease/ Diagnostics
1	Expression
14	General Information
34	General Stability
108	Inhibitors
1	kcat/KM [mM/s]
8	Ki Value [mM]
95	KM Value [mM]
24	Localization
14	Metals/Ions
49	Molecular Weight [Da]
86	Natural Substrates/ Products (Substrates)
11	Organic Solvent Stability
245	Organism
6	Pathway
73	PDB ID
111	pH Optimum
10	pH Range
22	pH Stability
13	Posttranslational Modification
90	Protein Variants
67	Purification (Commentary)
17	Reaction
1	Reaction Type
104	Reference
12	Renatured (Commentary)
148	Source Tissue
67	Specific Activity [micromol/min/mg]
8	Storage Stability
467	Substrates and Products (Substrate)
57	Subunits
111	Synonyms
1	Systematic Name
41	Temperature Optimum [°C]
3	Temperature Range [°C]
26	Temperature Stability [°C]
22	Turnover Number [1/s]

pH Stability

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pH Stability on EC 3.6.1.7 - acylphosphatase

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Gallus gallus

stable in acid solutions up to pH 1

246783

1.5 - 2

Sus scrofa

heart enzyme, 100% activity retained

246781

1.5 - 8.2

Bos taurus

brain enzyme, 24 h: no decrease of activity

246787

11.2 - 12

Gallus gallus

progressive inactivation, complete inactivation after 1 h

246783

2.5 - 11

Homo sapiens

stable between, enzyme is in its native state between, outside this pH range, stability of enzyme collapses abruptly, most probably due to excess of positive or negative charges present at low and high pH

246799

3 - 5.4

Oryctolagus cuniculus

stable 12 h , 37°C

246785

3.5 - 6.5

Homo sapiens

highest conformational stability between

246799

5.5

Homo sapiens

maximum stability near pH 5.5

246799

3 entries

9.5

Homo sapiens

highest stability against urea at pH 9.5

246799

additional information

10 entries