3.6.1.7: acylphosphatase
This is an abbreviated version!
For detailed information about acylphosphatase, go to the full flat file.
Word Map on EC 3.6.1.7
-
3.6.1.7
-
horse
-
native-like
-
ca2+-atpase
-
solfataricus
-
trifluoroethanol
-
phosphoenzyme
-
acylphosphates
-
thioflavine
-
ototoxicity
-
amyloid-like
-
protofibrils
-
medicine
- 3.6.1.7
- horse
-
native-like
- ca2+-atpase
- solfataricus
- trifluoroethanol
- phosphoenzyme
- acylphosphates
-
thioflavine
- ototoxicity
-
amyloid-like
-
protofibrils
- medicine
Reaction
Synonyms
1,3-diphosphoglycerate phosphatase, acetic phosphatase, acetyl phosphatase, acetylphosphatase, ACP, AcPDRo2, acyl phosphatase, acyl phosphate phosphohydrolase, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, erythrocyte/testis isozyme, Acylphosphate phosphohydrolase, acylphosphate phosphomonohydrolase, Acyp, ACYP2, carbamoylphosphate phosphatase, carbamyl phosphate phosphatase, Ch1, Ch2, GP 1-3, GP1, GP2, GP3, Ho 1-3, Ho1, Ho2, Ho3, human common-type acylphosphatase, Isozyme CH1, Isozyme CH2, Isozyme TU1, More, muscle-type acylphosphatase 2, native acylphosphatase, PhAcP, phosphatase, acyl, Sso AcP, SSO0887, T1, TT0497
ECTree
3.6.1.7 acylphosphataseAdvanced search results
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Reference on EC 3.6.1.7 - acylphosphatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Saudek, V.; Williams, R.J.P.
Secondary structure of acylphosphatase from rabbit skeletal muscle. A nuclear magnetic resonance study [published erratum appears in J Mol Biol 1988 Oct 5;203(3):835]
J. Mol. Biol.
199
233-237
1988
Oryctolagus cuniculus
Fujita, H.; Mizuno, Y.; Shiokawa, H.
Purification and properties of porcine testis acylphosphatase
J. Biochem.
102
1405-1414
1987
Gallus gallus, Equus caballus, Sus scrofa
Ohba, Y.; Minowa, O.; Mizuno, Y.; Shiokawa, H.
The primary structure of chicken muscle acylphosphatase isozyme Ch2
J. Biochem.
102
1221-1229
1987
Gallus gallus
Minowa, O.; Ohba, Y.; Mizuno, Y.; Shiokawa, H.
The primary structure of chicken muscle acylphosphatase isozyme Ch1
J. Biochem.
102
1213-1220
1987
Gallus gallus
Liguri, G.; Camici, G.; Manao, G.; Cappugi, G.; Nassi, P.; Modesti, A.; Ramponi, G.
A new acylphosphatase isoenzyme from human erythrocytes: purification, characterization, and primary structure
Biochemistry
25
8089-8094
1986
Homo sapiens
Ohba, Y.; Mizuno, Y.; Takasawa, T.; Shiokawa, H.
Two isozymes of chicken muscle acylphosphatase: purification and properties
J. Biochem.
98
909-919
1985
Gallus gallus, Oryctolagus cuniculus, Equus caballus, Sus scrofa
Mizuno, Y.; Takasawa, T.; Shiokawa, H.
Crystallization and properties of acylphosphatase from porcine skeletal muscle
J. Biochem.
96
313-320
1984
Sus scrofa
Liguri, G.; Nassi, P.; Camici, G.; Manao, G.; Cappugi, G.; Stefani, M.; Berti, A.; Ramponi, G.
Studies on synthesis and degradation rates and some molecular properties of guinea-pig muscle acylphosphatase
Biochem. J.
217
499-505
1984
Cavia porcellus, Equus caballus, Meleagris gallopavo
Manao, G.; Camici, G.; Stefani, M.; Berti, A.; Cappugi, G.; Liguri, G.; Nassi, P.; Ramponi, G.
Affinity chromatographic purification of horse muscle acylphosphatase: evidence of the existence of multiple molecular forms
Arch. Biochem. Biophys.
226
414-424
1983
Equus caballus
Stefani, M.; Liguri, G.; Berti, A.; Nassi, P.; Ramponi, G.
Hydrolysis by horse muscle acylphosphatase of (Ca2+ + Mg2+)-ATPase phosphorylated intermediate
Arch. Biochem. Biophys.
208
37-41
1981
Equus caballus
Ramponi, G.
1,3-Diphosphoglycerate phosphatase
Methods Enzymol.
42C
409-426
1975
Bos taurus, Saccharomyces cerevisiae, Gallus gallus, Oryctolagus cuniculus, Equus caballus, Homo sapiens, Sus scrofa
Ramponi, G.; Manao, G.; Camici, G.; White, G.F.
Inhibition of horse muscle acylphosphatase by pyridoxal 5'-phosphate
Biochim. Biophys. Acta
391
486-493
1975
Equus caballus
Satchell, D.P.N.; Spencer, N.; White, G.F.
Kinetic studies with muscle acylphosphatase
Biochim. Biophys. Acta
268
233-248
1972
Gallus gallus
Ramponi, G.; Nassi, P.; Cappugi, G.; Treves, C.; Manao, G.
Purification and some molecular properties of horse liver acyl phosphatase
Biochim. Biophys. Acta
284
485-496
1972
Equus caballus
Shiokawa, H.; Noda, L.
Isolation and crystallization of acyl phosphatase from rabbit muscle
J. Biol. Chem.
245
669-673
1970
Oryctolagus cuniculus
Ramponi, G.; Guerritore, A.; Treves, C.; Nassi, P.; Baccari, V.
Horse muscle acyl phosphatase: purification and some properties
Arch. Biochem. Biophys.
130
362-369
1969
Equus caballus
Raijman, L.; Grisolia, S.; Edelhoch, H.
Further purification and properties of brain acyl phosphatase
J. Biol. Chem.
235
2340-2342
1960
Bos taurus
Thunnissen, M.M.; Taddei, N.; Liguri, G.; Ramponi, G.; Nordlund, P.
Crystal structure of common type acylphosphatase from bovine testis
Structure
5
69-79
1997
Bos taurus
Stefani, M.; Degl'Innocenti, D.; Berti, A.; Cappugi, G.; Manao, G.; Camici, G.; Ramponi, G.
Purification and characterization of acylphosphatase erythrocyte isoenzyme from turkey muscle
J. Protein Chem.
9
633-640
1990
Meleagris gallopavo
Berti, A.; Tremori, E.; Pazzagli, L.; Degl'Innocenti, D.; Camici, G.; Cappugi, G.; Manao, G.; Ramponi, G.
Rat muscle acylphosphatase: purification, amino sequence, and immunological characterization
J. Protein Chem.
10
91-102
1991
Rattus norvegicus
Nassi, P.; Marchetti, E.; Nediani, C.; Liguri, G.; Ramponi, G.
Acylphosphatase induced modifications in the functional properties of erythrocyte membrane sodium pump
Biochim. Biophys. Acta
1147
19-26
1993
Homo sapiens
Pazzagli, L.; Ikram, U.K.; Liguri, G.; Taddei, N.; Gentilini, A.; Cecchi, C.; Manao, G.; Cappugi, G.
Purification, kinetic properties and primary structure of bovine erythrocyte acylphosphatase
Ital. J. Biochem.
42
233-245
1993
Bos taurus
Nassi, P.; Nediani, C.; Fiorillo, C.; Marchetti, E.; Liguri, G.; Ramponi,G.
Modifications induced by acylphosphatase in the functional properties of heart sarcolemma Na+,K+ pump
FEBS Lett.
337
109-113
1994
Bos taurus
Modesti, A.; Taddei, N.; Bucciantini, M.; Stefani, M.; Colombini, B.; Raugei, G.; Ramponi, G.
Expression, purification, and characterization of acylphosphatase muscular isoenzyme as fusion protein with glutathione S-transferase
Protein Expr. Purif.
6
799-805
1995
Homo sapiens
Taddei, N.; Modesti, A.; Bucciantini, M.; Stefani, M.; Magherini, F.; Vecchi, M.; Raugei, G.; Ramponi, G.
Properties of N-terminus truncated and C-terminus mutated muscle acylphosphatases
FEBS Lett.
362
175-179
1995
Homo sapiens
Modesti, A.; Taddei, N.; Chiti, F.; Bucciantini, M.; Magherini, F.; Rigacci, S.; Stefani, M.; Raugei, G.; Ramponi, G.
Properties of Cys21-mutated muscle acylphosphatases
J. Protein Chem.
15
27-34
1996
Homo sapiens
Chiarugi, P.; Raugei, G.; Fiaschi, T.; Taddei, L.; Camici, G.; Ramponi, G.
Characterization of a novel nucleolytic activity of acylphosphatases
Biochem. Mol. Biol. Int.
40
73-81
1996
Bos taurus, Homo sapiens, Meleagris gallopavo
Chiti, F.; Taddei, N.; van Nuland, N.A.J.; Magherini, F.; Stefani, M.; Ramponi, G.; Dobson, C.M.
Structural characterization of the transition state for folding of muscle acylphosphatase
J. Mol. Biol.
283
893-903
1998
Homo sapiens
Chiti, F.; van Nuland, N.A.J.; Taddei, N.; Magherini, F.; Stefani, M.; Ramponi, G.; Dobson, C.M.
Conformational stability of muscle acylphosphatase: the role of temperature, denaturant concentration, and pH
Biochemistry
37
1447-1455
1998
Homo sapiens
Stefani, M.; Ramponi, G.
Acylphosphate phosphohydrolases
Life Chem. Rep.
12
271-301
1995
Anas platyrhynchos, Bos taurus, Saccharomyces cerevisiae, Cavia porcellus, Gallus gallus, Oryctolagus cuniculus, Escherichia coli, Equus caballus, Chondrichthyes, Homo sapiens, Meleagris gallopavo, Rattus norvegicus, Sus scrofa, Vigna unguiculata
-
Miyazono, K.I.; Kudo, N.; Tanokura, M.
Cloning, purification, crystallization and preliminary crystallographic analysis of acylphosphatase from Pyrococcus horikoshii OT3
Acta Crystallogr. Sect. D
60
1135-1136
2004
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
Zuccotti, S.; Rosano, C.; Ramazzotti, M.; Degl‘Innocenti, D.; Stefani, M.; Manao, G.; Bolognesi, M.
Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase
Acta Crystallogr. Sect. D
60
1177-1179
2004
Drosophila melanogaster
Cheung, Y.Y.; Allen, M.D.; Bycroft, M.; Wong, K.B.
Crystallization and preliminary crystallographic analysis of an acylphosphatase from the hyperthermophilic archaeon Pyrococcus horikoshii
Acta Crystallogr. Sect. D
60
1308-1310
2004
Pyrococcus horikoshii
van Hoek, P.; Modesti, A.; Ramponi, G.; Kotter, P.; van Dijken, J.P.; Pron, J.T.
Human acylphosphatase cannot replace phosphoglycerate kinase in Saccharomyces cerevisiae
Antonie van Leeuwenhoek
80
11-17
2001
Homo sapiens
Degl'Innocenti, D.; Ramazzotti, M.; Marzocchini, R.; Chiti, F.; Raugei, G.; Ramponi, G.
Characterization of a novel Drosophila melanogaster acylphosphatase
FEBS Lett.
535
171-174
2003
Drosophila melanogaster
Taddei, N.; Capanni, C.; Chiti, F.; Stefani, M.; Dobson, C.M.; Ramponi, G.
Folding and aggregation are selectively influenced by the conformational preferences of the alpha-helices of muscle acylphosphatase
J. Biol. Chem.
276
37149-37154
2001
Homo sapiens
Zuccotti, S.; Rosano, C.; Bemporad, F.; Stefani, M.; Bolognesi, M.
Preliminary characterization of two different crystal forms of acylphosphatase from the hyperthermophile archaeon Sulfolobus solfataricus
Acta Crystallogr. Sect. F
F61
144-146
2005
Saccharolobus solfataricus
Yeung, R.C.; Lam, S.Y.; Wong, K.B.
Crystallization and preliminary crystallographic analysis of human common-type acylphosphatase
Acta Crystallogr. Sect. F
F62
80-82
2006
Homo sapiens
Cheung, Y.Y.; Lam, S.Y.; Chu, W.K.; Allen, M.D.; Bycroft, M.; Wong, K.B.
Crystal structure of a hyperthermophilic archaeal acylphosphatase from Pyrococcus horikoshii - structural insights into enzymatic catalysis, thermostability, and dimerization
Biochemistry
44
4601-4611
2005
Pyrococcus horikoshii (P84142), Pyrococcus horikoshii, Pyrococcus horikoshii DSM 12428 (P84142)
Miyazono, K.; Sawano, Y.; Tanokura, M.
Crystal structure of acylphosphatase from hyperthermophilic archaeon Pyrococcus horikoshii OT3
Proc. Jpn. Acad. Ser. B
80
439-442
2004
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
-
Miyazono, K.; Sawano, Y.; Tanokura, M.
Crystal structure and structural stability of acylphosphatase from hyperthermophilic archaeon Pyrococcus horikoshii OT3
Proteins
61
196-205
2005
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
Corazza, A.; Rosano, C.; Pagano, K.; Alverdi, V.; Esposito, G.; Capanni, C.; Bemporad, F.; Plakoutsi, G.; Stefani, M.; Chiti, F.; Zuccotti, S.; Bolognesi, M.; Viglino, P.
Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus
Proteins
62
64-79
2006
Saccharolobus solfataricus
Plakoutsi Georgi, P.G.; Bemporad Francesc, B.F.; Monti Mari, M.M.; Pagnozzi Daniel, P.D.; Pucci Pier, P.P.; Chiti Fabrizi, C.F.
Exploring the mechanism of formation of native-like and precursor amyloid oligomers for the native acylphosphatase from Sulfolobus solfataricus
Structure
14
993-1001
2006
Saccharolobus solfataricus (Q97ZL0), Saccharolobus solfataricus
Zuccotti, S.; Rosano, C.; Bemporad, F.; Stefani, M.; Bolognesi, M.
Preliminary characterization of two different crystal forms of acylphosphatase from the hyperthermophile archaeon Sulfolobus solfataricus
Acta Crystallogr. Sect. F
61
144-146
2005
Saccharolobus solfataricus
Bemporad, F.; Capanni, C.; Calamai, M.; Tutino, M.L.; Stefani, M.; Chiti, F.
Studying the folding process of the acylphosphatase from Sulfolobus solfataricus. A comparative analysis with other proteins from the same superfamily
Biochemistry
43
9116-9126
2004
Saccharolobus solfataricus
Plakoutsi, G.; Taddei, N.; Stefani, M.; Chiti, F.
Aggregation of the acylphosphatase from Sulfolobus solfataricus: the folded and partially unfolded states can both be precursors for amyloid formation
J. Biol. Chem.
279
14111-14119
2004
Saccharolobus solfataricus
Bemporad, F.; Vannocci, T.; Varela, L.; Azuaga, A.I.; Chiti, F.
A model for the aggregation of the acylphosphatase from Sulfolobus solfataricus in its native-like state
Biochim. Biophys. Acta
1784
1986-1996
2008
Saccharolobus solfataricus (Q97ZL0), Saccharolobus solfataricus
Bemporad, F.; Gsponer, J.; Hopearuoho, H.I.; Plakoutsi, G.; Stati, G.; Stefani, M.; Taddei, N.; Vendruscolo, M.; Chiti, F.
Biological function in a non-native partially folded state of a protein
EMBO J.
27
1525-1535
2008
Saccharolobus solfataricus
Soldi, G.; Bemporad, F.; Chiti, F.
The degree of structural protection at the edge beta-strands determines the pathway of amyloid formation in globular proteins
J. Am. Chem. Soc.
130
4295-4302
2008
Saccharolobus solfataricus (Q97ZL0), Saccharolobus solfataricus
Nishibori, E.; Nakamura, T.; Arimoto, M.; Aoyagi, S.; Ago, H.; Miyano, M.; Ebisuzaki, T.; Sakata, M.
Application of maximum-entropy maps in the accurate refinement of a putative acylphosphatase using 1.3 A X-ray diffraction data
Acta Crystallogr. Sect. D
64
237-247
2008
Thermus thermophilus (Q5SKS6), Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q5SKS6)
Michalak, P.; Ma, D.
The acylphosphatase (Acyp) alleles associate with male hybrid sterility in Drosophila
Gene
416
61-65
2008
Drosophila simulans, Drosophila mauritiana
Parrini, C.; Bemporad, F.; Baroncelli, A.; Gianni, S.; Travaglini-Allocatelli, C.; Kohn, J.E.; Ramazzotti, M.; Chiti, F.; Taddei, N.
The folding process of acylphosphatase from Escherichia coli is remarkably accelerated by the presence of a disulfide bond
J. Mol. Biol.
379
1107-1118
2008
Escherichia coli (P0AB65), Escherichia coli
Calamai, M.; Tartaglia, G.G.; Vendruscolo, M.; Chiti, F.; Dobson, C.M.
Mutational analysis of the aggregation-prone and disaggregation-prone regions of acylphosphatase
J. Mol. Biol.
387
965-974
2009
Homo sapiens
Motamedi-Shad, N.; Monsellier, E.; Torrassa, S.; Relini, A.; Chiti, F.
Kinetic analysis of amyloid formation in the presence of heparan sulfate: faster unfolding and change of pathway
J. Biol. Chem.
284
29921-29934
2009
Homo sapiens
Pagano, K.; Bemporad, F.; Fogolari, F.; Esposito, G.; Viglino, P.; Chiti, F.; Corazza, A.
Structural and dynamics characteristics of acylphosphatase from Sulfolobus solfataricus in the monomeric state and in the initial native-like aggregates
J. Biol. Chem.
285
14689-14700
2010
Saccharolobus solfataricus (Q97ZL0), Saccharolobus solfataricus
Hu, J.; Li, D.; Su, X.D.; Jin, C.; Xia, B.
Solution structure and conformational heterogeneity of acylphosphatase from Bacillus subtilis
FEBS Lett.
584
2852-2856
2010
Bacillus subtilis
Motamedi-Shad, N.; Garfagnini, T.; Penco, A.; Relini, A.; Fogolari, F.; Corazza, A.; Esposito, G.; Bemporad, F.; Chiti, F.
Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate
Nat. Struct. Mol. Biol.
19; 547-54
S1-2
2012
Homo sapiens
de Rosa, M.; Bemporad, F.; Pellegrino, S.; Chiti, F.; Bolognesi, M.; Ricagno, S.
Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase
FEBS J.
281
4072-4084
2014
Saccharolobus solfataricus (Q97ZL0), Saccharolobus solfataricus P2 (Q97ZL0)
Fusco, G.; De Simone, A.; Hsu, S.; Bemporad, F.; Vendruscolo, M.; Chiti, F.; Dobson, C.
1H, 13C and 15N resonance assignments of human muscle acylphosphatase
Biomol. NMR Assign.
6
27-29
2012
Homo sapiens
Nath, S.; Banerjee, R.; Sen, U.
A novel 8-nm protein cage formed by Vibrio cholerae acylphosphatase
J. Mol. Biol.
426
36-38
2014
Vibrio cholerae (A5F8G9), Vibrio cholerae, Vibrio cholerae O395 (A5F8G9), Vibrio cholerae O395
Lam, S.; Yeung, R.; Yu, T.; Sze, K.; Wong, K.
A rigidifying salt-bridge favors the activity of thermophilic enzyme at high temperatures at the expense of low-temperature activity
PLoS Biol.
9
e1001027
2011
Pyrococcus horikoshii (P84142), Pyrococcus horikoshii, Pyrococcus horikoshii OT-3 (P84142)
Elia, F.; Cantini, F.; Chiti, F.; Dobson, C.M.; Bemporad, F.
Direct conversion of an enzyme from native-like to amyloid-like aggregates within inclusion bodies
Biophys. J.
112
2540-2551
2017
Saccharolobus solfataricus (Q97ZL0), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97ZL0), Saccharolobus solfataricus JCM 11322 (Q97ZL0), Saccharolobus solfataricus ATCC 35092 (Q97ZL0), Saccharolobus solfataricus DSM 1617 (Q97ZL0)
Degl'Innocenti, D.; Ramazzotti, M.; Sarchielli, E.; Monti, D.; Chevanne, M.; Vannelli, G.B.; Barletta, E.
Oxadiazon affects the expression and activity of aldehyde dehydrogenase and acylphosphatase in human striatal precursor cells a possible role in neurotoxicity
Toxicology
411
110-121
2019
Homo sapiens (P14621), Homo sapiens
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