3.6.1.64: inosine diphosphate phosphatase

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For detailed information about inosine diphosphate phosphatase, go to the full flat file.

Reaction

Synonyms

(deoxy)inosine diphosphatase, NUD16, Nudt16, U8 snoRNA-decapping enzyme

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.64 inosine diphosphate phosphatase

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Results	in table
7	AA Sequence
2	Cloned(Commentary)
1	Crystallization (Commentary)
1	General Information
3	IC50 Value
6	Inhibitors
10	kcat/KM [mM/s]
3	Ki Value [mM]
10	KM Value [mM]
4	Localization
3	Metals/Ions
4	Organism
2	Pathway
20	PDB ID
1	Protein Variants
4	Reaction
3	Reference
3	Source Tissue
13	Substrates and Products (Substrate)
1	Subunits
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
10	Turnover Number [1/s]

General Information

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General Information on EC 3.6.1.64 - inosine diphosphate phosphatase

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

physiological function

Homo sapiens

Q96DE0

knockdown in HeLa MR cells causes cell cycle arrest in S-phase, reduces cell proliferation, and leads to increased accumulation of single-strand breaks in nuclear DNA as well as increased levels of inosine in RNA

720583