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3.6.1.6: nucleoside diphosphate phosphatase

This is an abbreviated version!
For detailed information about nucleoside diphosphate phosphatase, go to the full flat file.

Word Map on EC 3.6.1.6

Reaction

a nucleoside diphosphate
+
H2O
=
a nucleoside phosphate
+
phosphate

Synonyms

adenosine diphosphatase, adenosinepyrophosphatase, ADPase, At3g04080, At5g18280, AtAPY1, AtAPY2, calcium activated nucleotidase 1, Cant1, CD39, CDPase, E-NTPDase1, ecto-apyrase, ecto-ATPase, ecto-nucleotidase, ectonucleoside triphosphate diphosphohydrolase, ER-UDPase, GDA1, GDPase, GDPase/UDPase, GS52, guanosine 5'-diphosphatase, guanosine diphosphatase, IDPase, inosine 5'-diphosphatase, inosine diphosphatase, lumenal ecto-nucleoside di-phosphohydrolase, lumenal NDPase, lumenal uridine diphosphatase, Lysosomal apyrase-like protein of 70 kDa, MIG-23, More, NDPase, NTPDase, NTPDase1, NTPDase1/CD39, NTPDase2, NTPDase3, NTPDase4, NTPDase5, NTPDase6, NTPDase6 (CD39L2) nucleotidase, NTPDase8, nucleoside 5'-diphosphatase, Nucleoside diphosphatase, nucleoside diphosphate phosphatase, nucleoside diphosphate phosphohydrolase, nucleoside triphosphate diphosphohydrolase, nucleoside triphosphate diphosphohydrolase 1, nucleoside triphosphate diphosphohydrolase-1, PAE2307, Proto-oncogene cph, SA1684, SA1684 protein, thiaminpyrophosphatase, TPPase, TTHA1091, type B nucleoside diphosphatase, type L nucleoside diphosphatase, UDA-1, UDPase

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.6 nucleoside diphosphate phosphatase

Disease

Disease on EC 3.6.1.6 - nucleoside diphosphate phosphatase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma, Mucinous
Ultrastructural cytochemistry of human gastric cancer: electron microscopic observations of five organellae marker enzymes.
Adenoma, Pleomorphic
Phosphatase enzymes. Cytochemical study of pleomorphic adenoma and normal human salivary glands.
Alzheimer Disease
[Electron-cytochemical study of microglia in Alzheimer's disease and senile dementia]
Avitaminosis
[Enzyme activity of thiamine diphosphate biosynthesis and degradation in the mouse liver in the dynamics of B1 avitaminosis development]
Bone Resorption
Thiamine pyrophosphatase activity in the Golgi apparatus of calcitonin-treated osteoclasts.
Brain Diseases
The cytochemistry of anoxic and anoxicischemic encephalopathy in rats. III. Alterations in the neuronal Golgi apparatus identified by nucleoside diphosphatase activity.
Brain Ischemia
Postischemic alterations in ultrastructural cytochemistry of neuronal Golgi apparatus.
Carcinoma, Hepatocellular
Comparative studies on nucleoside diphosphatase of rat ascites hepatoma and rat liver: activity level, purification and properties.
[Various enzymes of isolated nuclear membranes and cell nuclei of the liver and hepatoma 27 of rats]
Dehydration
On the involvement of the Golgi apparatus and GERL in processing of secretion products and some enzyme activities in the rat pituitary mammotroph.
Dementia
Loss of endoplasmic reticulum-associated enzymes in affected brain regions in Huntington's disease and Alzheimer-type dementia.
Huntington Disease
Loss of endoplasmic reticulum-associated enzymes in affected brain regions in Huntington's disease and Alzheimer-type dementia.
Infections
Cytochemical localization of ATP diphosphohydrolase from Leishmania (Viannia) braziliensis promastigotes and identification of an antigenic and catalytically active isoform.
Novel Nucleoside Diphosphatase Contributes to Staphylococcus aureus Virulence.
Leishmaniasis
Cytochemical localization of ATP diphosphohydrolase from Leishmania (Viannia) braziliensis promastigotes and identification of an antigenic and catalytically active isoform.
Neoplasm Metastasis
A novel photoelectrochemical immunosensor by integration of nanobody and ZnO nanorods for sensitive detection of nucleoside diphosphatase kinase-A.
Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons.
Neoplasms
A novel photoelectrochemical immunosensor by integration of nanobody and ZnO nanorods for sensitive detection of nucleoside diphosphatase kinase-A.
ENTPD5: identification of splicing variants and their impact on cancer survival.
Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism.
Histochemical observations on NDPase and TPPase in cerebral tumours.
Overexpression of CD39 in hepatocellular carcinoma is an independent indicator of poor outcome after radical resection.
Phosphatase enzymes. Cytochemical study of pleomorphic adenoma and normal human salivary glands.
Sialyltransferase and nucleoside diphosphatase as markers for tumor monitoring.
Ticlopidine in its prodrug form is a selective inhibitor of human NTPDase1.
[Ultracytochemical study of the nucleoside phosphatase activity of nuclei of epithelial cells of the gastric mucosa and of stomach cancer cells in humans]
Peripheral Arterial Disease
Aberrant Circulating Levels of Purinergic Signaling Markers are Associated with Several Key Aspects of Peripheral Atherosclerosis and Thrombosis.
Pulmonary Disease, Chronic Obstructive
Is the purinergic pathway involved in the pathology of COPD? Decreased lung CD39 expression at initial stages of COPD.
Reperfusion Injury
Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury.
Scrapie
Ultrastructural cytochemical studies of cerebral microvasculature in scrapie infected mice.
Stomach Neoplasms
Ultrastructural cytochemical study of enzymes expressed by signet ring cells in gastric cancer.
Ultrastructural cytochemistry of human gastric cancer: electron microscopic observations of five organellae marker enzymes.
Thrombosis
Ticlopidine in its prodrug form is a selective inhibitor of human NTPDase1.