3.6.1.56: 2-hydroxy-dATP diphosphatase
This is an abbreviated version!
For detailed information about 2-hydroxy-dATP diphosphatase, go to the full flat file.
Word Map on EC 3.6.1.56
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3.6.1.56
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mutt
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triphosphates
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glycosylase
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8-oxo-dg
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sanitization
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8-oxo-2'-deoxyguanosine
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8-oxodgtp
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8-oxo-dgtpase
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dgtp
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hnpcc
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2-oh-datp
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8-ohdg
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8-hydroxy-2'-deoxyguanosine
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medicine
- 3.6.1.56
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mutt
- triphosphates
- glycosylase
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8-oxo-dg
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sanitization
- 8-oxo-2'-deoxyguanosine
- 8-oxodgtp
- 8-oxo-dgtpase
- dgtp
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hnpcc
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2-oh-datp
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8-ohdg
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8-hydroxy-2'-deoxyguanosine
- medicine
Reaction
Synonyms
(2'-deoxy) ribonucleoside 5'-triphosphate pyrophosphohydrolase, 8-oxo-dGTP hydrolase, hMTH1, MTH1, MTH2, MutT homologue 1, Nud2, Nudix hydrolase 2, NUDT1
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Application
Application on EC 3.6.1.56 - 2-hydroxy-dATP diphosphatase
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medicine
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increased amounts of 8-oxoguanine in the RNA, and decreased expression of MTH1 are observed in the hippocampi of patients suffering from Alzheimer's disease
medicine
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measurements of 8-oxo-dGTPase activity in brains, testes and kidneys may serve as a rough indicator rather than a quantifiable marker of radiation-induced oxidative stress