3.6.1.53: Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase

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For detailed information about Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, go to the full flat file.

Reaction

Synonyms

ADP-ribose/CDP-alcohol diphosphatase, ADPRibase-I, ADPRibase-II, ADPRibase-Mn, Adprm, cADPR phosphohydrolase, Mn(2+)-dependent ADP-ribose/CDP-alcohol pyrophosphatase, Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase, More

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase

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Results	in table
980	AA Sequence
3	Cloned(Commentary)
4	Crystallization (Commentary)
2	General Information
2	Inhibitors
69	kcat/KM [mM/s]
70	KM Value [mM]
10	Metals/Ions
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
8	Organism
7	pH Optimum
3	pH Range
1	pH Stability
1	pI Value
22	Protein Variants
4	Purification (Commentary)
2	Reaction
7	Reference
9	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
43	Substrates and Products (Substrate)
3	Subunits
15	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
69	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 3.6.1.53 - Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

o-phenanthroline

Rattus norvegicus

Q5M886

5 mM causes near full inactivation in 1.5 h

690823

additional information

Rattus norvegicus

Q5M886

incubation with 2.5 mM EDTA does not affect ADPRibase-Mn activity; not inhibitory: EDTA up to 2.5 mM

690823

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