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3.6.1.52: diphosphoinositol-polyphosphate diphosphatase

This is an abbreviated version!
For detailed information about diphosphoinositol-polyphosphate diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.52

Reaction

diphospho-myo-inositol polyphosphate
+
H2O
=
myo-inositol polyphosphate
+
phosphate

Synonyms

5PP-IP5 phosphatase, Aps protein, D250, DDP1, diphosphoinositol phosphate phosphohydrolase, diphosphoinositol phosphohydrolase, diphosphoinositol polyphosphate phosphatase, diphosphoinositol polyphosphate phosphohydrolase, diphosphoinositol polyphosphate phosphohydrolase 1, diphosphoinositol-polyphosphate phosphohydrolase, DIPP, DIPP1, DIPP2, DIPP3, g5Rp, More, muDIPP1, phosphatase, diphosphoinositol polyphosphate, poly-P endopolyphosphatase, Siw14

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.52 diphosphoinositol-polyphosphate diphosphatase

KM Value

KM Value on EC 3.6.1.52 - diphosphoinositol-polyphosphate diphosphatase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3
4-nitrophenyl phosphate
-
at pH 6.0 and 37°C
0.035
5-diphosphoinositol pentakisphosphate
-
at pH 6.0 and 37°C
0.13
5-phospho-D-ribosyl 1-diphosphate
-
in the presence of 10 mM Mg2+, at pH 9.0 and 26°C
0.004
adenosine tetraphosphate
-
in the presence of 10 mM Mg2+, at pH 9.0 and 26°C
0.000034
bisdiphosphoinositol tetrakisphosphate
-
-
0.018
diadenosine 5',5'''-P1,P6-hexaphosphate
-
in the presence of 10 mM Mg2+, at pH 9.0 and 26°C
0.0000042 - 0.0012
diphosphoinositol pentakisphosphate
0.011
guanosine tetraphosphate
-
in the presence of 10 mM Mg2+, at pH 9.0 and 26°C
additional information
additional information
-
Km-values for hydrolysis of Ap6A and Ap5A
-