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3.6.1.5: apyrase

This is an abbreviated version!
For detailed information about apyrase, go to the full flat file.

Word Map on EC 3.6.1.5

Reaction

a nucleoside 5'-diphosphate
+
H2O
=
a nucleoside 5'-phosphate
 +
phosphate

Synonyms

5' ectonucleotidase, 5'-nucleotidase, adenosine diphosphatase, adenosine pyrophosphatase, adenylpyrophophatase, ADPase, APT102, Apy, Apy 1, Apy 2, APY-1, APY1, APY10, APY2, APY2-type apyrase, APY4, APY5, APY6, APY7, APY8, APY9, Apyrase, apyrase 2, APYRASE2, At1g14230, At1g14240, At1g14250, At2g02970, At3g04080, At5g18280, AtAPY1, AtAPY2, AtAPY3, AtAPY4, AtAPY5, AtAPY6, ATP diphosphohydrolase, ATP diphosphohyrolase, ATP-diphosphatase, ATP-diphosphohydrolase, ATP-diphosphohydrolase 2, ATPase, ATPase 2, ATPDase, ATPDase1, ATPDase2, BjAPY2, Ca2+-activated nucleoside diphosphatase, CApy, CD39, CD39 antigen, CD39-like ATP diphosphohydrolase, CD39L1, Def11, E-NTPDase, E-NTPDase 3, ecto-5'-nucleotidase, ecto-apyrase, ecto-ATP diphosphohydrolase, ecto-ATP-diphosphohydrolase, ecto-ATPase, ecto-ATPDase, ecto-NTPDase, Ecto-NTPDase1, ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleoside triphosphate diphosphohydrolase 1, ecto-nucleoside triphosphate diphosphohydrolase 2, ecto-nucleoside triphosphate diphosphohydrolase1, ecto-nucleoside triphosphate diphosphohydrolase2, ecto-nucleoside triphosphate diphosphohydrolase3, ecto-nucleoside triphosphate diphosphohydrolase8, ecto-nucleoside triphosphate-diphosphohydrolase, ecto-nucleoside-triphosphate-diphosphohydrolase, ectoapyrase, ectonucleoside triphosphate diphosphohydrolase, ectonucleoside triphosphate diphosphohydrolase 3, ectonucleotidase, ENTPD1, ENTPD2, ENTPD3, Entpd8, ENTPDase1, esctonucleoside triphosphate diphosphohydrolase 1, esctonucleoside triphosphate diphosphohydrolase 2, esctonucleoside triphosphate diphosphohydrolase 8, Golgi nucleoside diphosphatase, GS50, GS52, HB6, hCD39, LALP1, LBRM_15_0030, LicNTPDase-2, LINJ_15_0030, LmjF15.0030, LmNTPDase 1, Lpg1905, lumenal NDPase, Lymphoid cell activation antigen, More, MP67, MpAPY2, NTPase, NTPD1, NTPDase, NTPDase 1, NTPDase 2, NTPDase 3, NTPDase 5, NTPDase 6, NTPDase 8, NTPDase1, NTPDase1/CD39, NTPDase2, NTPDase2/CD39L1, NTPDase3, NTPDase8, nucleoside triphosphatase, nucleoside triphosphate diphosphohydrolase, nucleoside triphosphate diphosphohydrolase 1, nucleoside triphosphate diphosphohydrolase 2, nucleoside triphosphate diphosphohydrolase 8, nucleoside triphosphate diphosphohydrolase-1, NDPDase 1, nucleoside triphosphate diphosphohydrolase-2, nucleoside triphosphate diphosphohydrolase-3, nucleoside triphosphate diphosphohydrolase-8, nucleoside triphosphate disphophohydrolase, nucleoside triphosphate-diphosphohydrolase, nucleotide triphosphate diphosphohydrolase, PeAPY2, potato-specific apyrase, PsAPY1, psNTP9, r-NTPDase 1, r-NTPDase 2, r-NTPDase 3, r-NTPDase 8, Ruviapyrase, SCAN-1, snake venom apyrase, SolCD39/NTPDase1, soluble apyrase, soluble calcium-activated nucleotidase 1, soluble CD39, TaAPY1, TaAPY2, TaAPY3-1, TaAPY3-2, TaAPY3-3, TaAPY3-4, TaAPY5, TaAPY6, TaAPY7, XAPY

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.5 apyrase

Turnover Number

Turnover Number on EC 3.6.1.5 - apyrase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
86 - 1384
1,N6-etheno-ADP
682 - 1642
1,N6-Etheno-ATP
70 - 328
2'(3')-O-(2,4,6-trinitrophenyl)adenosine 5'-diphosphate
191 - 982
2'(3')-O-(2,4,6-trinitrophenyl)adenosine 5'-triphosphate
23 - 828
3'(2')-O-(methylanthranoyl)adenosine 5'-diphosphate
800 - 965
3'(2')-O-(methylanthranoyl)adenosine 5'-triphosphate
0.96
8-oxo-dGTP
-
pH 8.5, 37°C
31.1 - 248.6
ADP
40.5
AMPCPP
recombinant wild-type enzyme, pH 7.4, 25°C
100 - 2200
ATP
1.5 - 2222
dATP
490 - 2174
dCTP
0.74 - 3019
dGTP
455 - 2841
dTTP
82.6 - 103.7
GDP
80.9
GTP
recombinant wild-type enzyme, pH 7.4, 25°C
79.9
IDP
recombinant wild-type enzyme, pH 7.4, 25°C
105.3
ITP
recombinant wild-type enzyme, pH 7.4, 25°C
0.0225 - 0.119
N-[5-[4-carboxy-3-(3-oxo-9,9a-dihydro-3H-xanthen-9-yl)benzamido]pentyl]adenosine 5'-triphosphate
80.2
TDP
recombinant wild-type enzyme, pH 7.4, 25°C
595 - 1101
thio-dATP
80.9 - 93
UDP
103.4 - 121.2
UTP