3.6.1.44: oligosaccharide-diphosphodolichol diphosphatase

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For detailed information about oligosaccharide-diphosphodolichol diphosphatase, go to the full flat file.

Reaction

Synonyms

DLO diphosphatase, DLODP, oligosaccharide diphosphodolichol diphosphatase, oligosaccharide-diphosphodolichol diphosphatase, oligosaccharide-diphosphodolichol pyrophosphatase

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.44 oligosaccharide-diphosphodolichol diphosphatase

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2	Activating Compound
1	CAS Registry Number
3	Disease/ Diagnostics
5	IC50 Value
17	Inhibitors
4	Localization
5	Metals/Ions
2	Natural Substrates/ Products (Substrates)
3	Organism
1	pH Optimum
1	pH Stability
1	Reaction
1	Reaction Type
3	Reference
3	Source Tissue
17	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 3.6.1.44 - oligosaccharide-diphosphodolichol diphosphatase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

bacitracin

Saccharomyces cerevisiae

-

80% inhibition at 10 mM

289083

citronellyl diphosphate

Homo sapiens

-

-

757368

diphosphate

Saccharomyces cerevisiae

-

total inhibition at 10 mM

289083

farnesyl diphosphate

Homo sapiens

-

-

757368

geranyl diphosphate

Homo sapiens

-

-

757368

geranylgeranyl diphosphate

Homo sapiens

-

-

757368

GlcNAc-diphosphosolanesol

Homo sapiens

-

-

757368

GlcNAc2-diphosphosolanesol

Homo sapiens

-

-

757368

Hg2+

Homo sapiens

-

-

757368

isopentenyl diphosphate

Homo sapiens

-

-

757368

NAD+

Saccharomyces cerevisiae

-

total inhibition at 10 mM

289083

phosphate

Saccharomyces cerevisiae

-

35% inhibition at 10 mM

289083

solanesol

Homo sapiens

-

-

757368

solanesyl diphosphate

Homo sapiens

-

-

757368

solanesyl phosphate

Homo sapiens

-

-

757368

vanadate

Homo sapiens

-

-

757368

additional information

Homo sapiens

-

not inhibited by NaF and EDTA

757368

-