3.6.1.43: dolichyldiphosphatase
This is an abbreviated version!
For detailed information about dolichyldiphosphatase, go to the full flat file.
Reaction
Synonyms
acid PPase, acid pyrophosphatase, CAX4, Dol-P-P phosphatase, dol-P-P phosphohydrolase, Dol-PP phosphatase, dolichol diphosphatase, Dolicholpyrophosphatase, dolichyl diphosphate phosphohydrolase, dolichyl pyrophosphatase, dolichyl pyrophosphate phosphatase, dolichyl-diphosphate phosphatase, DPPase
ECTree
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Inhibitors
Inhibitors on EC 3.6.1.43 - dolichyldiphosphatase
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additional information
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bacitracin fails to inhibit the acid PPase
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bacitracin
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complete inhibition; no inhibition when preincubating with EDTA
divalent cations
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strong or complete inhibition at concentrations of 5 mM for all tested ions
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phosphate
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strong inhibition, 5 mM causes more than 60% loss of activity