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3.6.1.42: guanosine-diphosphatase

This is an abbreviated version!
For detailed information about guanosine-diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.42

Reaction

GDP
+
H2O
=
GMP
+
phosphate

Synonyms

APY1, DIPP1, E-NTPDase, ecto-nucleoside triphosphate diphosphohydrolase, gda1p (GDA1 gene product), Gdap1, Gdp1p, GDPase, guanosine diphosphatase, KlGdap1, phosphatase, guanosine di-, UDPase

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.42 guanosine-diphosphatase

Inhibitors

Inhibitors on EC 3.6.1.42 - guanosine-diphosphatase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
azide
-
42% inhibition at 10 mM
fluoride
-
27% inhibition at 10 mM
GDP
-
hydrolysis of UDP
inositol 1-[(phosphorylmethyl)phosphonic acid]-2,3,4,5,6-pentaphosphate
competitive
inositol 1-[(phosphorylmethyl)phosphonic acid]-2,3,5,6-tetraphosphate
competitive
inositol 4-butyl-1-[(phosphorylmethyl)phosphonic acid]-2,3,5,6-tetraphosphate
competitive
UDP
-
hydrolysis of GDP
vanadate
-
54% inhibition at 1 mM
additional information
-
not inhibited by NGXT191 and dithiothreitol
-