3.6.1.40: guanosine-5'-triphosphate,3'-diphosphate phosphatase

This is an abbreviated version!
For detailed information about guanosine-5'-triphosphate,3'-diphosphate phosphatase, go to the full flat file.

Word Map on EC 3.6.1.40

3.6.1.40

polyphosphate

aeolicus

tetraphosphate

aquifex

alarmone

5'-diphosphate

Reaction

guanosine 5'-triphosphate 3'-diphosphate

Synonyms

CJJ81176_0377, CJJ81176_1251, exopolyphosphatase/guanosine pentaphosphate phosphohydrolase, GppA, guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase, guanosine pentaphosphatase, guanosine pentaphosphate phosphatase, guanosine pentaphosphate phosphohydrolase, guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, More, phosphatase, guanosine 5'-triphosphate 3'-diphosphate 5'-, pppGpp 5'-phosphohydrolase, pppGpp phosphohydrolase, pppGpp-5'-phosphohydrolase, PPX/GPPA enzyme, PPX1

ECTree

3 Hydrolases

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.1.40 guanosine-5'-triphosphate,3'-diphosphate phosphatase

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Results	in table
4343	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
5	Crystallization (Commentary)
4	General Information
3	Inhibitors
6	KM Value [mM]
6	Metals/Ions
3	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
14	Organism
5	Pathway
7	PDB ID
1	pH Optimum
9	Protein Variants
5	Purification (Commentary)
2	Reaction
1	Reaction Type
12	Reference
4	Specific Activity [micromol/min/mg]
1	Storage Stability
24	Substrates and Products (Substrate)
3	Subunits
25	Synonyms
1	Systematic Name
4	Turnover Number [1/s]

Reference

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Reference on EC 3.6.1.40 - guanosine-5'-triphosphate,3'-diphosphate phosphatase

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209848

Keasling, J.D.; Bertsch, L.; Kornberg, A.

Guanosine pentaphosphate phosphohydrolase of Escherichia coli is a long-chain exopolyphosphatase

Proc. Natl. Acad. Sci. USA

7029-7033

1993

Escherichia coli, Escherichia coli CA10

8394006

289072

Hara, A.; Sy, J.

Guanosine 5'-triphosphate, 3'-diphosphate 5'-phosphohydrolase. Purification and substrate specificity

J. Biol. Chem.

258

1678-1683

1983

Escherichia coli, Escherichia coli JF1599

6130093

289074

Reizer, J.; Reizer, A.; Saier, M.H.

Exopolyphosphate phosphatase and guanosine pentaphosphate phosphatase belong to the sugar kinase/actin/hsp 70 superfamily

Trends Biochem. Sci.

247-248

1993

Escherichia coli

8212131

654764

Kristensen, O.; Laurberg, M.; Liljas, A.; Kastrup, J.S.; Gajhede, M.

Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family

Biochemistry

8894-8900

2004

Aquifex aeolicus

15248747

688392

Kristensen, O.; Ross, B.; Gajhede, M.

Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp

J. Mol. Biol.

375

1469-1476

2008

Aquifex aeolicus

18155044

735334

Malde, A.; Gangaiah, D.; Chandrashekhar, K.; Pina-Mimbela, R.; Torrelles, J.B.; Rajashekara, G.

Functional characterization of exopolyphosphatase/guanosine pentaphosphate phosphohydrolase (PPX/GPPA) of Campylobacter jejuni

Virulence

521-533

2014

Campylobacter jejuni (A0A0H3PAT6), Campylobacter jejuni (A0A0H3PES2), Campylobacter jejuni, Campylobacter jejuni 81-176 (A0A0H3PAT6), Campylobacter jejuni 81-176 (A0A0H3PES2)

24569519

756714

Song, H.; Dharmasena, M.N.; Wang, C.; Shaw, G.X.; Cherry, S.; Tropea, J.E.; Jin, D.J.; Ji, X.

Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori

FEBS J.

287

1865-1885

2019

Helicobacter pylori (C7BYL8), Escherichia coli (P25552), Helicobacter pylori B38 (C7BYL8)

31679177