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3.6.1.27: undecaprenyl-diphosphate phosphatase

This is an abbreviated version!
For detailed information about undecaprenyl-diphosphate phosphatase, go to the full flat file.

Word Map on EC 3.6.1.27

Reaction

ditrans,octacis-undecaprenyl diphosphate
+
H2O
=
ditrans,octacis-undecaprenyl phosphate
 +
phosphate

Synonyms

bacA, BcrC, C55-isoprenyl diphosphatase, C55-isoprenyl pyrophosphatase, C55-PP phosphatase, C55-PP pyrophosphatase, Dolicholpyrophosphatase, HP0851, HupA, isoprenyl pyrophosphatase, More, PbrB, PgpB, SMU.244, Und-pp phosphatase, undecaprenyl diphosphate phosphatase, undecaprenyl pyrophosphatase, undecaprenyl pyrophosphate phosphatase, undecaprenyl-pyrophosphate phosphatase, UPP phosphatase, Upp-P, UPP-Pase, UppP, YbjG, YeiU

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.27 undecaprenyl-diphosphate phosphatase

Inhibitors

Inhibitors on EC 3.6.1.27 - undecaprenyl-diphosphate phosphatase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(5-bromo-2-[[3-(octyloxy)phenyl]methoxy]phenyl)phosphonic acid
-
-
2-(N-methyl-3-(octyloxy)benzamido)phenylphosphonic acid
-
-
2-methoxy-6-[3-(octyloxy)benzamido]benzoic acid
-
-
2-[3,4-bis(2-methoxyethoxy)benzamido]-5-bromobenzoic acid
-
-
2-[3-(hexyloxy)benzamido]benzoic acid
-
-
2-[3-(octyloxy)benzamido]-5-(trifluoromethoxy)benzoic acid
-
most potent inhibitor
2-[3-(octyloxy)benzamido]-5-phosphonobenzoic acid
-
-
2-[3-(octyloxy)benzamido]benzoic acid
-
-
2-[methyl[3-(octyloxy)benzoyl]amino]benzoic acid
-
-
3,4,5-trimethoxy-2-[3-(octyloxy)benzamido]benzoic acid
-
-
3-fluoro-2-[3-(octyloxy)benzamido]benzoic acid
-
-
3-[3-(hexyloxy)benzamido]-4-hydroxybenzoic acid
-
-
3-[3-(octyloxy)benzamido]benzene-1,2-dicarboxylic acid
-
-
3-[3-(octyloxy)benzamido]benzoic acid
-
-
4,5-difluoro-2-[3-(octyloxy)benzamido]benzoic acid
-
-
4-hydroxy-3-[3-(octyloxy)benzamido]benzoic acid
-
-
4-[3-(octyloxy)benzamido]benzene-1,3-dicarboxylic acid
-
-
5-(diethoxyphosphoryl)-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-(methanesulfonyl)-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-bromo-2-[3-(3,3-dimethylbut-1-yn-1-yl)benzamido]benzoic acid
-
-
5-bromo-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-chloro-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-fluoro-2-(3-(octyloxy)benzamido)benzoic acid
-
-
5-fluoro-2-[3-(hexyloxy)benzamido]benzoic acid
-
-
5-fluoro-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-hydroxy-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-methoxy-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-methoxy-4-(2-methoxyethoxy)-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-nitro-2-[3-(octyloxy)benzamido]benzoic acid
-
-
5-[3-(octyloxy)benzamido]benzene-1,3-dicarboxylic acid
-
-
bacitracin
Ca2+
about less than 10% residual activity at 10 mM
Cu2+
complete inhibition at 10 mM
DTNB
-
slight inhibition
Mn2+
about 90% residual activity at 10 mM
N-(2-carbamoylphenyl)-3-(octyloxy)benzamide
-
-
n-butanol
-
-
n-Propanol
-
inhibitory at concentrations above 1.5 M
p-chloromercuriphenylsulfonic acid
-
-
tetrahydrofuran
-
inhibitory at concentrations above 2 M
tripropeptin C
tripropeptin C can potentially inhibit C55-PP phosphatase activity, which plays a crucial role in the lipid cycle of peptidoglycan synthesis
Zn2+
about less than 10% residual activity at 10 mM
[2-[3-(octyloxy)benzamido]phenyl]phosphonic acid
-
-
[3-[3-(octyloxy)benzamido]phenyl]phosphonic acid
-
-
additional information
-