3.6.1.18: FAD diphosphatase

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For detailed information about FAD diphosphatase, go to the full flat file.

Reaction

Synonyms

5'-nucleotidase, FAD diphosphatase, FAD pyrophosphatase, FADppase, flavin adenine dinucleotide pyrophosphatase, flavine adenine dinucleotide pyrophosphatase, Ftp_Ec, Ftp_Tp-like, metal-dependent FAD pyrophosphatase, Mg2+-dependent FAD pyrophosphatase, More, nucleotide phosphodiesterase, nucleotide pyrophosphatase, riboflavin adenine dinucleotide pyrophosphatase, riboflavine adenine dinucleotide pyrophosphatase, TP0796

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.18 FAD diphosphatase

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Results	in table
7	Activating Compound
41	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
2	Crystallization (Commentary)
46	Disease/ Diagnostics
10	General Information
1	IC50 Value
59	Inhibitors
10	KM Value [mM]
13	Localization
22	Metals/Ions
11	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
23	Organism
2	Pathway
13	pH Optimum
5	pH Range
1	Posttranslational Modification
17	Protein Variants
6	Purification (Commentary)
1	Reaction
2	Reaction Type
19	Reference
1	Renatured (Commentary)
8	Source Tissue
10	Specific Activity [micromol/min/mg]
2	Storage Stability
39	Substrates and Products (Substrate)
3	Subunits
30	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
3	Temperature Stability [°C]

Activating Compound

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Activating Compound on EC 3.6.1.18 - FAD diphosphatase

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ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

ADP

Vigna radiata var. radiata

-

reactivates aged enzyme, activating up to 0.01 mM

209917

AMP

Vigna radiata var. radiata

-

activates at concentrations below 0.01 mM

209919

Ca2+

Treponema pallidum

O83774

may replace Mg2+/Mn2+ but with lower catalytic efficiencies

734210

Mg2+

Treponema pallidum

O83774

or Mn2+, most efficiently support FAD hydrolysis

734210

Mn2+

Treponema pallidum

O83774

or Mg2+, most efficiently support FAD hydrolysis

734210

Ni2+

Treponema pallidum

O83774

may replace Mg2+/Mn2+ but with lower catalytic efficiencies

734210

p-chloromercuribenzoate

Vigna radiata var. radiata

-

-

209917