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3.5.5.5: Arylacetonitrilase

This is an abbreviated version!
For detailed information about Arylacetonitrilase, go to the full flat file.

Word Map on EC 3.5.5.5

Reaction

4-Chlorophenylacetonitrile
+ 2 H2O =
4-chlorophenylacetate
+
NH3

Synonyms

Arylacetonitrilase, arylacetonitrile-hydrolyzing nitrilase, arylacetonitrile-specific nitrilase, blr3397, enantioselective arylacetonitrilase, GPnor51, NIT, NitA, NitAd, NitAk2, NitAn, NitMp, NitP, nitrilase, nitrilase PpL19, Nitrilase, arylaceto-, NitTv

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.5 In nitriles
                3.5.5.5 Arylacetonitrilase

Inhibitors

Inhibitors on EC 3.5.5.5 - Arylacetonitrilase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-dipyridyl
-
weak
3-Methyl-2-benzothiazolinone hydrazone
-
weak
4-hydroxyphenylacetic acid
-
-
8-hydroxyquinoline
-
weak
Ag2+
-
strong
ascorbic acid
-
-
Ba2+
-
8% inhibition at 5 mM
Ca2+
about 50% inhibition at 1 mM
Cs+
about 50% inhibition at 1 mM
D-cycloserine
-
weak
diethyldithiocarbamate
-
-
Disodium 4,5-dihydroxy-m-benzene-disulfonate
-
weak
dithiothreitol
about 50% inhibition at 1 mM
DTNB
-
strong
hydroxylamine
-
weak
iodoacetate
-
weak
L-cysteine
-
-
Li+
-
11% inhibition at 5 mM
Mg2+
91% inhibition at 1 mM
N-ethylmaleimide
-
-
p-chloromercuribenzoate
-
strong
phenylhydrazine
-
-
Semicarbazide
-
weak
additional information
-