3.5.5.5: Arylacetonitrilase

This is an abbreviated version!
For detailed information about Arylacetonitrilase, go to the full flat file.

Reaction

Synonyms

Arylacetonitrilase, arylacetonitrile-hydrolyzing nitrilase, arylacetonitrile-specific nitrilase, blr3397, enantioselective arylacetonitrilase, GPnor51, NIT, NitA, NitAd, NitAk2, NitAn, NitMp, NitP, nitrilase, nitrilase PpL19, Nitrilase, arylaceto-, NitTv

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.5 In nitriles

                3.5.5.5 Arylacetonitrilase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
8	Activating Compound
16	AA Sequence
9	Application
1	CAS Registry Number
20	Cloned(Commentary)
3	Expression
8	General Information
3	General Stability
61	Inhibitors
1	Ki Value [mM]
30	KM Value [mM]
5	Metals/Ions
23	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
5	Organic Solvent Stability
157	Organism
1	Oxidation Stability
23	pH Optimum
8	pH Range
17	pH Stability
80	Protein Variants
14	Purification (Commentary)
3	Reaction
4	Reaction Type
71	Reference
15	Specific Activity [micromol/min/mg]
8	Storage Stability
370	Substrates and Products (Substrate)
23	Subunits
44	Synonyms
1	Systematic Name
22	Temperature Optimum [°C]
6	Temperature Range [°C]
25	Temperature Stability [°C]
6	Turnover Number [1/s]

Application

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Application on EC 3.5.5.5 - Arylacetonitrilase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Application Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

biotechnology

2 entries

synthesis

7 entries

biotechnology

Pseudomonas putida

B0LAW4

preparation of optically pure carboxylic acids

694107

biotechnology

Pseudomonas putida MTCC 5110

-

preparation of optically pure carboxylic acids

-

synthesis

Alcaligenes faecalis

-

nitrilases are important industrial enzymes that convert nitriles directly into the corresponding carboxylic acids

719629

synthesis

Pseudomonas fluorescens

-

recombinant cells expressing the enzyme are promising catalysts for the synthesis of stable chiral quaternary carbon centers from ketones

718648

synthesis

Aspergillus niger

-

the enzyme is promising for the enantioretentive transformation of (S)-mandelonitrile

757638

synthesis

Alcaligenes faecalis

-

the whole cell arylacetonitrilase of Alcaligenes faecalis MTCC 12629 is employed to develop a bioprocess for the synthesis of 4-hydroxyphenylacetic acid from 4-hydroxyphenylacetonitrile. A fed batch process designed at 500 ml with five feedings of substrate results in 150 mM product formation using 18 U/ml whole cells nitrilase (16 mg/ml dcw) at 45°C and a volumetric and catalytic productivity of 23 g/l and 4.13 g/g dcw/h

758206

synthesis

Pseudomonas fluorescens EBC191

-

recombinant cells expressing the enzyme are promising catalysts for the synthesis of stable chiral quaternary carbon centers from ketones

-

synthesis

Alcaligenes faecalis MTCC 12629

-

the whole cell arylacetonitrilase of Alcaligenes faecalis MTCC 12629 is employed to develop a bioprocess for the synthesis of 4-hydroxyphenylacetic acid from 4-hydroxyphenylacetonitrile. A fed batch process designed at 500 ml with five feedings of substrate results in 150 mM product formation using 18 U/ml whole cells nitrilase (16 mg/ml dcw) at 45°C and a volumetric and catalytic productivity of 23 g/l and 4.13 g/g dcw/h

-

synthesis

Alcaligenes faecalis ZJUTB10

-

nitrilases are important industrial enzymes that convert nitriles directly into the corresponding carboxylic acids

-