3.5.4.6: AMP deaminase

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For detailed information about AMP deaminase, go to the full flat file.

Reaction

Synonyms

5'-adenosine monophosphate deaminase, 5'-adenylic acid deaminase, 5-adenylate deaminase, 5-adenylic acid deaminase, 5-AMP aminohydrolase, 5-AMP deaminase, adenosine 5-monophosphate deaminase, adenosine 5-phosphate aminohydrolase, adenosine 5-phosphate deaminase, adenosine monophosphate deaminase, adenosine monophosphate deaminase 3, adenosine monophosphate deaminase-1, adenosine-5'-monophosphate deaminase, adenyl deaminase, adenylate aminohydrolase, adenylate deaminase, adenylate desaminase, adenylic acid deaminase, adenylic deaminase, AMP aminase, AMP deaminase, AMP deaminase 3, AMP deaminase H-type, AMP deaminase isoform E, AMP deaminase type 3, AMP deaminase1, AMP-aminohydrolase, AMP-deaminase, AmpD, AMPD1, AMPD2, AMPD3, AMPDA, deaminase, adenylate, embryonic factor 1, EMBRYONIC FACTOR1, Erythrocyte AMP deaminase, FAC1, Heart-type AMPD, muscle AMP deaminase, Myoadenylate deaminase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.4 In cyclic amidines

                3.5.4.6 AMP deaminase

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Results	in table
52	Activating Compound
8499	AA Sequence
10	Application
1	CAS Registry Number
10	Cloned(Commentary)
2	Crystallization (Commentary)
1392	Disease/ Diagnostics
4	Expression
11	General Information
10	General Stability
27	IC50 Value
130	Inhibitors
1	Ki Value [mM]
35	KM Value [mM]
2	Localization
25	Metals/Ions
26	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
112	Organism
6	Pathway
36	pH Optimum
7	pH Range
7	pH Stability
2	Posttranslational Modification
6	Protein Variants
43	Purification (Commentary)
2	Reaction
2	Reaction Type
106	Reference
99	Source Tissue
28	Specific Activity [micromol/min/mg]
7	Storage Stability
94	Substrates and Products (Substrate)
19	Subunits
101	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
2	Temperature Range [°C]
8	Temperature Stability [°C]

pH Stability

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pH Stability on EC 3.5.4.6 - AMP deaminase

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pH STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

10

Aspergillus oryzae

-

4°C, 6 h, about 90% loss of activity

756756

3

Aspergillus oryzae

-

4°C, 6 h, about 45% loss of activity

756756

4 - 8

Aspergillus oryzae

-

4°C, 6 h, less than 10% loss of activity

756756

5

Aspergillus oryzae

-

after incubation at 4 °C for 1 h, less than 50 % of residual activity remains below pH 5.0

755821

5.5 - 7.5

Cyprinus carpio

-

slowly reduces its activity on the both sides of the optimum pH 6.3, at pH values of 5.5, 7.0 and 7.5, AMPD shows 13, 31 and 65% lower activity, respectively

686221

6.8

Oryctolagus cuniculus

-

highest stability

209672

7

Aspergillus oryzae

-

after incubation at 4 °C for 1 h, less than 50 % of residual activity remains above pH 7.0

755821