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3.5.4.6: AMP deaminase

This is an abbreviated version!
For detailed information about AMP deaminase, go to the full flat file.

Word Map on EC 3.5.4.6

Reaction

AMP
+
H2O
=
IMP
+
NH3

Synonyms

5'-adenosine monophosphate deaminase, 5'-adenylic acid deaminase, 5-adenylate deaminase, 5-adenylic acid deaminase, 5-AMP aminohydrolase, 5-AMP deaminase, adenosine 5-monophosphate deaminase, adenosine 5-phosphate aminohydrolase, adenosine 5-phosphate deaminase, adenosine monophosphate deaminase, adenosine monophosphate deaminase 3, adenosine monophosphate deaminase-1, adenosine-5'-monophosphate deaminase, adenyl deaminase, adenylate aminohydrolase, adenylate deaminase, adenylate desaminase, adenylic acid deaminase, adenylic deaminase, AMP aminase, AMP deaminase, AMP deaminase 3, AMP deaminase H-type, AMP deaminase isoform E, AMP deaminase type 3, AMP deaminase1, AMP-aminohydrolase, AMP-deaminase, AmpD, AMPD1, AMPD2, AMPD3, AMPDA, deaminase, adenylate, embryonic factor 1, EMBRYONIC FACTOR1, Erythrocyte AMP deaminase, FAC1, Heart-type AMPD, muscle AMP deaminase, Myoadenylate deaminase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.6 AMP deaminase

Source Tissue

Source Tissue on EC 3.5.4.6 - AMP deaminase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
similar level of expression of AMPD2, but greater expression of AMPD3 than in neurons
Manually annotated by BRENDA team
-
the study fails to confirm a survival benefit among heart failure patients carrying the AMPD1 T-allele (C34T)
Manually annotated by BRENDA team
-
activity of adenosine monophosphate deaminase is significantly higher in chicken of the fast-growing type than in the slow-growing French "Label Rouge" type, and in heavy line typ
Manually annotated by BRENDA team
-
lower level of expression of both AMPD2 and AMPD3 than neurons, and a lower expression of AMPD3 than astrocytes
Manually annotated by BRENDA team
significantly increased FAC1 expression in the zygote, early embryo and endosperm. During somatic embryogenesis, a high level of FAC1 expression is observed in developing embryos including putative embryogenic cells. FAC1 represents one of the earliest expressed genes known in plants. It may act through AMP depletion to provide sufficient energy for the zygote to proceed through development
Manually annotated by BRENDA team
-
AMP-deaminase plays a role in formation of NH3 by endometrium stroma cells and its release into extracellular space during acetylcholine stimulation
Manually annotated by BRENDA team
significantly increased FAC1 expression in the zygote, early embryo and endosperm
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
-
from forebrain. In neurons AMPD2 exhibits 8fold greater expression than AMPD3
Manually annotated by BRENDA team
-
a macrophage-like cell line sensitive to anthrax lethal toxin, i.e. LeTx, induced death
Manually annotated by BRENDA team
-
smooth muscle
Manually annotated by BRENDA team
significantly increased FAC1 expression in the zygote, early embryo and endosperm
Manually annotated by BRENDA team